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Subject Two teen boys become the first ever to contract meningitis from chickenpox vaccine: Live virus reactivated over a DECADE after they received the
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Original Message Doctors believe they have discovered the first known case of the chickenpox vaccine reactivating in two 14-year-old boys and causing meningitis.

According to the paper, published in the journal Pediatrics, both teens had received the recommended two doses of the varicella vaccine as children.

The vaccine, which was developed in the 1970s and first distributed in the US in 1995, has been proven to be safe and effective.

However, in very rare cases in immunocompromised patients, the live virus can reactivate and can causes shingles, pneumonia, hepatitis or meningitis, which is an inflammation of the membranes that cover the brain and spinal cord.

Previous cases of the virus reactivating and causing meningitis years after vaccination - a phenomenon known as vOka varicella - have been reported in children who received just one dose of the vaccine.


'Less is known about...reactivation in older children after the [two]-dose vaccine series,' the authors write.

According to the paper, only one of the boys had a compromised immune system due to a history of leukemia.

Doctors said he experienced temporary symptoms of numbness and slurred speech.

However, the other boy was otherwise healthy. Both were treated with acyclovir, an antiviral drug that treats chickenpox, shingles and cold scores.

'Pediatricians should be aware of the potential of vOka varicella to reactivate and cause clinically significant central nervous system disease in vaccinated children and adolescents,' the authors said.

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