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Ineffective flu vaccine in Australia. Aged hit hardest with 7 deaths one home; 6 deaths in another home despite receiving higher strength doses

 
jwh125
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09/11/2017 03:44 AM
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Ineffective flu vaccine in Australia. Aged hit hardest with 7 deaths one home; 6 deaths in another home despite receiving higher strength doses
A trend in recent years has seen decreasing vaccine effectiveness. As low as 9% for those over 65 years of age during 2012-13 season. [link to www.cdc.gov (secure)]
Mid season 2014-15 CDC reported--The predominance of drifted influenza A (H3N2) viruses has resulted in reduced vaccine effectiveness this season. Updated interim estimates of data collected from November 10, 2014 through January 30, 2015 indicate that overall the influenza vaccine was 19% (95% confidence interval (CI) = 7%-29%) effective in preventing medical visits across all age groups, -- [link to www.cdc.gov (secure)]
Did you get that, "all age groups". But what is most incredible is that the known exact type of influenza that eventually took dominance in America was the type that had just been widely reported as having devastated Australia in their last flu season. Australia's season ends as ours begins. You would think there is some written in stone rule that says "Hey, look at the flu in other countries that have seasons ending" in deciding which vaccines varieties to choose. Maybe they do that. Who knows for sure.
Fifty percent effectiveness had become acceptable. But it is not being realized. Australia has just emerged from a flu season that may show 9% or less effectiveness for the elderly. Authorities are just now looking for a reason why this years flu confirmations were 2.5 times higher as last year. An official word on the effectiveness of the vaccine is expected in 2-3 weeks. One headline reads POOR FLU VACCINE CALLS FOR CHANGE. Another read, ANOTHER FLU VACCINE NEEDED, SAYS EXPERT. The CDC is already putting out CYA blurbs about why vaccines sometimes don't work.
Apparently it got so bad that blood type O- pos transfusion donations became scarce. [link to www.sbs.com.au]
Officials are saying that the vaccine chosen was a good match for the type of flu that circulated yet it had no or little effect in preventing the virus. So either this is a lie or a serious half-truth. I think that the truth will be that it was a near match but not a match. Close is not enough with this rapidly changing H3N2 Clade 3 virus. New subclades have been recently indentified that make the vaccine effectiveness a real crapshoot.
Read below for more insight.

During last winter U.S. flu season a new subclade was mentioned with very little discussion as to it's contribution to overall flu numbers. Kinda like a footnote. Week 43 ending Oct 29, 2016 surveillance report said--Genetic group 3C.2a includes a newly emerging subgroup known as 3C.2a1. --
The subclade to H3N2, 3c.2a1 is possibly responsible for the ineffectiveness of last years flu vaccine in Israel. H3N2 has the ability to make quick changes in its makeup to evade vaccines. A recent study in all age groups".Journal of virology two other similar subclades (3c.2a2) of which one is yet unnamed. See- Genetic divergence of Influenza A(H3N2) amino acid substitutions mark the beginning of the 2016–2017 winter season in Israel. -- For example:
(Less than 20% rule) --The influenza A(H3N2) viruses demonstrated genetic divergence from the vaccine strain into three separate subgroups within the 3C.2a clade. One resembled the new 3C.2a1 subclade, one resembled the recently proposed 3C.2a2 subclade and the other was not previously described. Diversity was observed within each subgroup, in terms of additional amino acid substitutions.
......
The detection of three clear and different groups of AA substitutions, suggests that continued characterization of influenza A(H3N2) is necessary to see which group will prevail, prior to the decision regarding the future influenza vaccine composition.
Yes I am aware Israel is Northern Hemisphere. I am citing this to provide scientific background on why MAYBE the Australians vaccine performed miserably. It is potentially (likely) applicable to the effectiveness of the North American vaccine for the upcoming season.--

This is what WHO had said in recommending their flu vaccine composition,--Antigenic characterisation of influenza A(H3N2) subclade 3C.2a viruses continues to be technically challenging but most recent 3C.2a viruses were well inhibited by ferret antisera raised against the current northern hemisphere vaccine component.--
Sorry this is so long but will probably get banned again so Ibwanted to get as much info as possible beforehand.
....
As both influenza A(H1N1)pdm09 and A(H3N2) viruses continue to drift, it is difficult to estimate with confidence the proportions of circulating viruses next season and the expected protection by the recommended vaccine components. The technical difficulties in virus culture, characterisation and egg propagation of influenza A(H3N2) viruses make the selection of new vaccine components difficult.----

Last Edited by jwh125 on 09/13/2017 03:32 PM
Anonymous Coward
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09/11/2017 04:30 AM
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Re: Ineffective flu vaccine in Australia. Aged hit hardest with 7 deaths one home; 6 deaths in another home despite receiving higher strength doses
this year more people were given the flu shot, and also they would get the flu a week or so later. Spreading it to others. Medical staff and educators are forced to have the shots of forced out of that career. these people have major contact with the population and therefore spreading the flu.
I got a head cold last week the first in years, I got it from friends who are in the medical field and only had their flu shots only to come down weeks later to spread it. Flu shots I think are for profit so many elderly died from the flu this year and why aged care promotes flu shots to all clients. yes we all know how well an elderly can cope when they are infected with the germ dead.
Anonymous Coward (OP)
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09/11/2017 03:13 PM
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Re: Ineffective flu vaccine in Australia. Aged hit hardest with 7 deaths one home; 6 deaths in another home despite receiving higher strength doses
True. One article talks about 4-5 elderly in two separate nursing facilities catching the flu and dying. I had just wanted to check how the Southern Hemisphere had gone as it our Northern flu season usually mirrors theirs. I need to now research this further, particularly the nature and sub-clade (type) of H3N2 flu they were dealing with.
Anonymous Coward
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09/11/2017 03:26 PM
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Re: Ineffective flu vaccine in Australia. Aged hit hardest with 7 deaths one home; 6 deaths in another home despite receiving higher strength doses
The more vaccinations given, the more disease. That's how it works.

You know why they had to stop the small pox vaccine? It was causing too much smallpox.

Now that they are pushing flu vaccine, we can reasonably expect an increase of the flu to go round.
Anonymous Coward
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09/11/2017 03:27 PM
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Re: Ineffective flu vaccine in Australia. Aged hit hardest with 7 deaths one home; 6 deaths in another home despite receiving higher strength doses
Waiting for the "vaccines" are good shills.
beeches

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09/11/2017 03:28 PM

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Re: Ineffective flu vaccine in Australia. Aged hit hardest with 7 deaths one home; 6 deaths in another home despite receiving higher strength doses
bump
Liberalism is totalitarianism with a human face – Thomas Sowell
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09/11/2017 03:43 PM
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Re: Ineffective flu vaccine in Australia. Aged hit hardest with 7 deaths one home; 6 deaths in another home despite receiving higher strength doses
Australia reports worst flu season on record.
[link to www.news.com.au]
Anonymous Coward (OP)
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09/11/2017 08:28 PM
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Re: Ineffective flu vaccine in Australia. Aged hit hardest with 7 deaths one home; 6 deaths in another home despite receiving higher strength doses
True. One article talks about 4-5 elderly in two separate nursing facilities catching the flu and dying. I had just wanted to check how the Southern Hemisphere had gone as it our Northern flu season usually mirrors theirs. I need to now research this further, particularly the nature and sub-clade (type) of H3N2 flu they were dealing with.
 Quoting: Anonymous Coward 69246718


During last winter U.S. flu season a new subclade was mentioned with very little discussion as to it's contribution to overall flu numbers. Kinda like a footnote. Week 43 ending Oct 29, 2016 surveillance report said--Genetic group 3C.2a includes a newly emerging subgroup known as 3C.2a1. --
The subclade to H3N2, 3c.2a1 is possibly responsible for the ineffectiveness of last years flu vaccine in Israel. H3N2 has the ability to make quick changes in its makeup to evade vaccines. A recent study in Journal of virology two other similar subclades (3c.2a2) of which one is yet unnamed. See- Genetic divergence of Influenza A(H3N2) amino acid substitutions mark the beginning of the 2016–2017 winter season in Israel. -- For example:
(Less than 20% rule) --The influenza A(H3N2) viruses demonstrated genetic divergence from the vaccine strain into three separate subgroups within the 3C.2a clade. One resembled the new 3C.2a1 subclade, one resembled the recently proposed 3C.2a2 subclade and the other was not previously described. Diversity was observed within each subgroup, in terms of additional amino acid substitutions.
......
The detection of three clear and different groups of AA substitutions, suggests that continued characterization of influenza A(H3N2) is necessary to see which group will prevail, prior to the decision regarding the future influenza vaccine composition.
Yes I am aware Israel is Northern Hemisphere. I am citing this to provide scientific background on why MAYBE the Australians vaccine performed miserably. It is potentially (likely) applicable to the effectiveness of the North American vaccine for the upcoming season.--

This is what WHO had said in recommending their flu vaccine composition,--Antigenic characterisation of influenza A(H3N2) subclade 3C.2a viruses continues to be technically challenging but most recent 3C.2a viruses were well inhibited by ferret antisera raised against the current northern hemisphere vaccine component.--
Sorry this is so long but will probably get banned again so Ibwanted to get as much info as possible beforehand.
....
As both influenza A(H1N1)pdm09 and A(H3N2) viruses continue to drift, it is difficult to estimate with confidence the proportions of circulating viruses next season and the expected protection by the recommended vaccine components. The technical difficulties in virus culture, characterisation and egg propagation of influenza A(H3N2) viruses make the selection of new vaccine components difficult.----
Anonymous Coward (OP)
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09/12/2017 03:10 AM
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Re: Ineffective flu vaccine in Australia. Aged hit hardest with 7 deaths one home; 6 deaths in another home despite receiving higher strength doses
The more vaccinations given, the more disease. That's how it works.

You know why they had to stop the small pox vaccine? It was causing too much smallpox.

Now that they are pushing flu vaccine, we can reasonably expect an increase of the flu to go round.
 Quoting: Anonymous Coward 75494324


The reason they stopped was because it had been essentially eradicated in America.





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