QAnon: It's on, don't panic ii

I would go to the doctor and get a test to see if I had the antibodies where I could have had the COVID-19 virus which proves you are immune to it and make it public. This should work, if not they can be suited, or get an emergency stay until you get a report on the immunity from the virus. This could work for many of them. The infusion which gives antibodies can be used I believe. I know Florida gives these, also here in my state.

His hair is different, he normally wears it almost shaved on the sides, if this is him, he looks better with this style.

Well, the states here told them don't try passing that deal because it is against the constitution of our country.
As for green think money for a few at the top.

Christmas - Remember that decorated elevator with the Q on the stocking and Santa with the Hammer? Perhaps Christmas will indeed be where the past proves the future (or future proves the past, depending on which angle you’re seeing it from).

And I still think that right around the 4 year delta of Q’s first post, we will see this will be the year that Podesta gets arrested.

I’m with you on the timing, Des. Any more of waiting and things will get very ugly and that will be just the opposite of everything Q and Q+ wanted for this country.

Terminator ...!

Absolute bonkers. Wonder how well they fair against a bucket of paint.

It was just enough time to get the message out! Hell, if the NY Times can do this drop and then retract trick, so can the good guys.

Communist Genocide of 150 million 1917-1985 11m

Mao Ze-Dong (China, 1958-61 and 1966-69, Tibet 1949-50) 49-78,000,000
Lenin, Jozef Stalin USSR, 50,000,000 (the gulags plus the purges plus Ukraine's famine)
Pol Pot (Cambodia, 1975-79) 2,100,000
Kim Il Sung (North Korea, 1948-94) 2.5 million (purges and concentration camps)
Menghistu (Ethiopia, 1975-78) 2,500,000
and so on.................


[link to www.youtube.com (secure)]

Update: The radical trans activist employees who reportedly forced their way into a meeting at Netflix have had their positions reinstated following public pressure.

https://twitter.com/_/status/1448323462842535954

Have you seen the Black Mirror episode with the mechanical dogs?

The arrogant bastard says ask yourself 3 questions, then proceeds to say that basically, everybody must get it! People come into contact with other members of the public on the street, every day!

Sad to say, but Australia is screwed. I thought they would fight, but the communism has been ingrained in them for far too long.

At some point AOC worked at a media company out west, I can't remember the state except this was in her background.

What The Heck Is Going On

digs on research for N-Acetyl Cysteine....

[link to pubmed.ncbi.nlm.nih.gov (secure)]
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[link to pubmed.ncbi.nlm.nih.gov (secure)]
Review Ther Clin Risk Manag
. 2020 Nov 2;16:1047-1055. doi: 10.2147/TCRM.S273700. eCollection 2020.
N-Acetylcysteine to Combat COVID-19: An Evidence Review
Zhongcheng Shi 1 2, Carlos A Puyo 3
Affiliations expand
PMID: 33177829 PMCID: PMC7649937 DOI: 10.2147/TCRM.S273700
Free PMC article
Abstract
The novel coronavirus disease (COVID-19) is caused by a virus (SARS-Cov-2) and is known for inducing multisystem organ dysfunction associated with significant morbidity and mortality. Current therapeutic strategies for COVID-19 have failed to effectively reduce mortality rate, especially for elderly patients. A newly developed vaccine against SARS-Cov-2 has been reported to induce the production of neutralizing antibodies in young volunteers. However, the vaccine has shown limited benefit in the elderly, suggesting an age-dependent immune response. As a result, exploring new applications of existing medications could potentially provide valuable treatments for COVID-19. N-acetylcysteine (NAC) has been used in clinical practice to treat critically ill septic patients, and more recently for COVID-19 patients. NAC has antioxidant, anti-inflammatory and immune-modulating characteristics that may prove beneficial in the treatment and prevention of SARS-Cov-2. This review offers a thorough analysis of NAC and discusses its potential use for treatment of COVID-19.

Keywords: COVID-19; N-acetylcysteine; SARS-Cov-2.

© 2020 Shi and Puyo.
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[link to pubmed.ncbi.nlm.nih.gov (secure)]

Case Reports Eur J Pharmacol
. 2020 Oct 15;885:173494. doi: 10.1016/j.ejphar.2020.173494. Epub 2020 Aug 20.
Application of methylene blue -vitamin C -N-acetyl cysteine for treatment of critically ill COVID-19 patients, report of a phase-I clinical trial
Daryoush Hamidi Alamdari 1, Ahmad Bagheri Moghaddam 2, Shahram Amini 3, Mohammad Reza Keramati 4, Azam Moradi Zarmehri 5, Aida Hamidi Alamdari 6, Mohammadamin Damsaz 6, Hamed Banpour 4, Amir Yarahmadi 7, George Koliakos 8
Affiliations expand
PMID: 32828741 PMCID: PMC7440159 DOI: 10.1016/j.ejphar.2020.173494
Free PMC article
Abstract
COVID-19 is a global catastrophic event that causes severe acute respiratory syndrome. The mechanism of the disease remains unclear, and hypoxia is one of the main complications. There is no currently approved protocol for treatment. The microbial threat as induced by COVID-19 causes the activation of macrophages to produce a huge amount of inflammatory molecules and nitric oxide (NO). Activation of macrophages population into a pro-inflammatory phenotype induces a self-reinforcing cycle. Oxidative stress and NO contribute to this cycle, establishing a cascade inflammatory state that can kill the patient. Interrupting this vicious cycle by a simple remedy may save critical patients' lives. Nitrite, nitrate (the metabolites of NO), methemoglobin, and prooxidant-antioxidant-balance levels were measured in 25 ICU COVID-19 patients and 25 healthy individuals. As the last therapeutic option, five patients were administered methylene blue-vitamin C-N-acetyl Cysteine (MCN). Nitrite, nitrate, methemoglobin, and oxidative stress were significantly increased in patients in comparison to healthy individuals. Four of the five patients responded well to treatment. In conclusion, NO, methemoglobin and oxidative stress may play a central role in the pathogenesis of critical COVID-19 disease. MCN treatment seems to increase the survival rate of these patients. Considering the vicious cycle of macrophage activation leading to deadly NO, oxidative stress, and cytokine cascade syndrome; the therapeutic effect of MCN seems to be reasonable. Accordingly, a wider clinical trial has been designed. It should be noted that the protocol is using the low-cost drugs which the FDA approved for other diseases. TRIAL REGISTRATION NUMBER: NCT04370288.

Keywords: COVID-19; Coronavirus; Methylene blue; N-acetyl cysteine; Treatment; Vitamin C.

Copyright © 2020 Elsevier B.V. All rights reserved.

Conflict of interest statement
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[link to pubmed.ncbi.nlm.nih.gov (secure)]

Med Hypotheses
. 2020 Apr 22;140:109778. doi: 10.1016/j.mehy.2020.109778. Online ahead of print.
N-acetyl-cysteine may prevent COVID-19-associated cytokine storm and acute respiratory distress syndrome
Stelios F Assimakopoulos 1, Markos Marangos 2
Affiliations expand
PMID: 32344315 PMCID: PMC7195028 DOI: 10.1016/j.mehy.2020.109778
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[link to pubmed.ncbi.nlm.nih.gov (secure)]

Editorial Future Microbiol
. 2020 Jul;15:959-962. doi: 10.2217/fmb-2020-0074. Epub 2020 Jul 14.
N-acetylcysteine as a potential treatment for COVID-19
Rangel-Méndez Jorge-Aarón 1, Moo-Puc Rosa-Ester 1
Affiliations expand
PMID: 32662664 PMCID: PMC7359418 DOI: 10.2217/fmb-2020-0074
---------------------------

[link to pubmed.ncbi.nlm.nih.gov (secure)]

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Cleve Clin J Med
. 2020 Jun 8. doi: 10.3949/ccjm.87a.ccc046. Online ahead of print.
What is the role of supplementation with ascorbic acid, zinc, vitamin D, or N-acetylcysteine for prevention or treatment of COVID-19?
Seth R Bauer 1, Aanchal Kapoor 2, Mary Rath 3, Suma A Thomas 4
Affiliations expand
PMID: 32513807 DOI: 10.3949/ccjm.87a.ccc046
Free article
Abstract
Several agents intended to supplement dietary intake or endogenous molecules may have a theoretical role in preventing or treating COVID-19. Because of their potential to influence immune response, ascorbic acid (vitamin C), zinc, vitamin D, and N-acetylcysteine have been hypothesized to be useful for prevention or treatment of COVID-19. The authors outline the biologic plausibility, applicable clinical data, and potential role of each of these agents.

Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.
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Case Reports Clin Immunol
. 2020 Oct;219:108544. doi: 10.1016/j.clim.2020.108544. Epub 2020 Jul 22.
Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine
Homam Ibrahim 1, Andras Perl 2, Deane Smith 3, Tyler Lewis 3, Zachary Kon 3, Ronald Goldenberg 3, Kinan Yarta 3, Cezar Staniloae 3, Mathew Williams 3
Affiliations expand
PMID: 32707089 PMCID: PMC7374140 DOI: 10.1016/j.clim.2020.108544
Free PMC article
Abstract
Glucose 6-phosphate dehydrogenase (G6PD) deficiency facilitates human coronavirus infection due to glutathione depletion. G6PD deficiency may especially predispose to hemolysis upon coronavirus disease-2019 (COVID-19) infection when employing pro-oxidant therapy. However, glutathione depletion is reversible by N-acetylcysteine (NAC) administration. We describe a severe case of COVID-19 infection in a G6PD-deficient patient treated with hydroxychloroquine who benefited from intravenous (IV) NAC beyond reversal of hemolysis. NAC blocked hemolysis and elevation of liver enzymes, C-reactive protein (CRP), and ferritin and allowed removal from respirator and veno-venous extracorporeal membrane oxygenator and full recovery of the G6PD-deficient patient. NAC was also administered to 9 additional respirator-dependent COVID-19-infected patients without G6PD deficiency. NAC elicited clinical improvement and markedly reduced CRP in all patients and ferritin in 9/10 patients. NAC mechanism of action may involve the blockade of viral infection and the ensuing cytokine storm that warrant follow-up confirmatory studies in the setting of controlled clinical trials.

Keywords: C-reactive protein; COVID-19; Coronavirus 19; Extracorporeal membrane oxygenation; Ferritin; Glucose 6-phosphate dehydrogenase; Glutathione; Mechanistic target of rapamycin; N-acetylcysteine; Respirator.

Copyright © 2020 Elsevier Inc. All rights reserved.
--------------------------------------

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Curr Pharm Biotechnol
. 2021;22(12):1584-1590. doi: 10.2174/1389201021999201228212043.
The Potential Mechanism of N-acetylcysteine in Treating COVID-19
Nan Zhou 1, Xiaofan Yang 1, Aie Huang 2, Zhenbing Chen 1
Affiliations expand
PMID: 33371832 DOI: 10.2174/1389201021999201228212043
Abstract
N-Acetylcysteine (NAC) has been proposed to be used to treat Coronavirus Disease 2019 (COVID-19). By reviewing the existing pathological studies of COVID-19, it was found that abundant mucus secretion, formation of a hyaline membrane (supportive of acute respiratory distress syndrome), and interstitial fibrous exudation may be important characteristics of COVID-19 and pathological targets of drug therapy. In addition, multiple extrapulmonary organ injuries in COVID- 19 may be associated with cytokine storm. NAC is an important antioxidant and anti-inflammatory drug. NAC has been demonstrated to have mucolytic effects in bronchitis, relieve respiratory failure in acute respiratory distress syndrome, and inhibit fibrous exudation in interstitial lung disease in clinical studies. These findings suggest that NAC may have a therapeutic effect on the pathological targets of COVID-19. Furthermore, NAC decreases TNF-α, IL-1β, IL-6, IL-8, IL-10, and IL-17 serum levels in patients with sepsis, severe burns, acute liver failure, or peritoneal dialysis and may also reduce cytokine storm in COVID-19. The antiviral effect of NAC on other respiratory viruses may also benefit COVID-19 patients. Summarizing the potential mechanisms of NAC in treating COVID-19 suggests that the role of NAC in COVID-19 treatment is worthy of further research.

Keywords: COVID-19; N-acetylcysteine; SARS-CoV-2; drug; mechanism; treatment..

Copyright© Bentham Science Publishers; For any queries, please email at [email protected].
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"New King James Version
and that no one may buy or sell except one who has the mark or the name of the beast, or the number of his name."
Revelation 13:17

Start with the messenger. Find a tree. Find a rope!

I go one further - Being chased and then held down by those hounds of hell while the “authorities” stab me with the clot shot…

https://twitter.com/_/status/1448124138640580611

Wow. TN Board of Medical Examiners adopted a new policy threatening doctors with loss of their license if they spread "COVID-19 Vaccine disinformation or misinformation". They demand docs share info "consensus driven for the betterment of public health". Only groupthink allowed!

11:11 PM · Oct 12, 2021

Thread: Biden employer vaccine mandate a step closer to reality as OSHA submits rule text to OMB for review

Welp, this is where the real “fun” will begin.

Thread: This epic “ From my dad who is a pilot about the current situation with Southwest airlines”

In all honesty, that wasn't necessary. The General Duty Clause could be used as a vaccine mandate because of the way it is worded.

This move by OSHA is just dotting 'i' and crossing 't' to make sure the Occupational Safety and Health Review Commission finds in favor of OSHA every single time this matter comes up when proposed citations are levied by inspectors against businesses.

By explicitly making a 'rule', this squashes most avenues companies and employees have to fight. Department of Labor (home of OSHA) is just as corrupt as any other governmental agency.

Hasbro CEO Brian Goldner dead at 58 just days after going on medical leave

Toymaker Hasbro on Tuesday said longtime chairman and chief executive officer Brian Goldner died, two days after he went on medical leave.

In a statement last year, Goldner said he had been under continued medical treatment following his cancer diagnosis in 2014.

Board member and former CEO of marketing firm InnerWorkings Rich Stoddart has replaced Goldner on an interim basis.

Goldner, 58, joined Hasbro in 2000 and was appointed CEO in 2008, the company said.

“He expanded the company beyond toys and games into television, movies, digital gaming and beyond,” Hasbro said.

Goldner oversaw the company as sales recovered and surged after the COVID pandemic.

Goldner also served on the board of directors of ViacomCBS.

[link to nypost.com (secure)]