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HPV Vaccines Safe And Effective

 
Reality420
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05/09/2018 02:56 PM
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HPV Vaccines Safe And Effective
[link to www.bbc.com]
BBC NEWS
Health 9 May 2018
"HPV jab safe and effective, study finds
The analysis by the Cochrane Group provides solid evidence that should reassure parents considering having their daughters immunised, say experts.

It looked at 26 trials involving more than 73,000 girls and women.

Serious side-effects following the vaccine were rare.
...
What is the HPV vaccine?
Human Papilloma Virus (HPV) - which can cause abnormal changes to the cells of the cervix or neck of the womb that, if untreated, can lead to cancer."

########################################
[link to medicalxpress.com (secure)]
Medical Xpress
May 8, 2018, Wiley
"Does HPV vaccination prevent the development of cervical cancer?
New evidence published today in the Cochrane Library shows that human papilloma virus (HPV) vaccines protect against cervical lesions in young women, particularly in those who are vaccinated between the ages of 15 and 26. It also summarizes findings on harms that have been assessed in randomized controlled trials.
...
There are many different types of HPV. ... Two of these high-risk types (HPV16 and HPV18) account for about 70% all cases of cervical cancer worldwide. ... Because cervical cancer can take several years to develop, regulatory bodies and international health agencies such as the World Health Organization (WHO) regard cervical lesions as the preferred outcome measure for HPV vaccine trials.

A team of Cochrane researchers has summarized results of 26 studies in 73,428 women conducted across all continents over the last eight years. ... The studies were well-designed, randomizing the women to either HPV vaccine or a placebo.
...
The review looked at two groups of people: women who are free of high-risk HPV at the time of vaccination and all women regardless of HPV status at vaccination.
...
... They found that in young women who did not carry HPV, vaccination reduced the risk of developing precancer. About 164 per 10,000 women who got placebo and 2 per 10,000 women who got the vaccine went on to develop cervical precancer.

The researchers also looked at data from all enrolled women regardless whether they were free of high-risk HPV at vaccination or not. Among women aged 15 to 26 years, vaccines reduced the risk of cervical precancer associated with HPV16/18 from 341 to 157 per 10,000. HPV vaccination reduced also the risk for any precancer lesions from 559 to 391 per 10,000.
...
The evidence also shows that the vaccines do not appear to increase the risk of serious side effects which was about 7% in both HPV vaccinated or control groups."

.
########################################
Cochrane Press Release:
[link to www.cochrane.org]
Cochrane
News and Events
Does HPV vaccination prevent the development of cervical cancer? Are there harms associated with being vaccinated?

10.1002/14651858.CD009069.pub3
New evidence published today in the Cochrane Library shows that human papilloma virus (HPV) vaccines protect against cervical lesions in young women, particularly in those who are vaccinated between the ages of 15 and 26. It also summarizes findings on harms that have been assessed in randomized controlled trials.
...
A team of Cochrane researchers has summarized results of 26 studies in 73,428 women conducted across all continents over the last eight years. Most women in the studies were under the age of 26 years old, although three trials recruited women between 25 and 45 years. The studies were well-designed, randomizing the women to either HPV vaccine or a placebo.
...
The review looked at two groups of people: women who are free of high-risk HPV at the time of vaccination and all women regardless of HPV status at vaccination. The effects of the vaccine were measured as precancer associated with HPV16/18 and precancer irrespective of HPV type. The review looked at data from ten trials assessing cervical lesion data at between three and a half to eight years after vaccination.

... They found that in young women who did not carry HPV, vaccination reduced the risk of developing precancer. About 164 per 10,000 women who got placebo and 2 per 10,000 women who got the vaccine went on to develop cervical precancer."

.
########################################
The abstract for the actual Cochrane study:
[link to cochranelibrary-wiley.com]
Cochrane Library
Cochrane Database of Systematic Reviews
Prophylactic vaccination against human papillomaviruses to prevent cervical cancer and its precursors

Marc Arbyn, Lan Xu, Cindy Simoens, Pierre PL Martin-Hirsch
First published: 9 May 2018
DOI: 10.1002/14651858.CD009069.pub3

"Abstract
Background

Persistent infection with high-risk human papillomaviruses (hrHPV) types is causally linked with the development of cervical precancer and cancer. HPV types 16 and 18 cause approximately 70% of cervical cancers worldwide.
...
Main results
We included 26 trials (73,428 participants). Ten trials, with follow-up of 1.3 to 8 years, addressed protection against CIN/AIS. Vaccine safety was evaluated over a period of 6 months to 7 years in 23 studies. Studies were not large enough or of sufficient duration to evaluate cervical cancer outcomes. All but one of the trials was funded by the vaccine manufacturers. We judged most included trials to be at low risk of bias.
...
hrHPV negative
HPV vaccines reduce CIN2+, CIN3+, AIS associated with HPV16/18 compared with placebo in adolescent girls and women aged 15 to 26. There is high-certainty evidence that vaccines lower CIN2+ from 164 to 2/10,000 (RR 0.01 (0 to 0.05)) and CIN3+ from 70 to 0/10,000 (RR 0.01 (0.00 to 0.10). There is moderate-certainty evidence that vaccines reduce the risk of AIS from 9 to 0/10,000 (RR 0.10 (0.01 to 0.82).

HPV vaccines reduce the risk of any CIN2+ from 287 to 106/10,000 (RR 0.37 (0.25 to 0.55), high certainty) and probably reduce any AIS lesions from 10 to 0/10,000 (RR 0.1 (0.01 to 0.76), moderate certainty)."

>>>>> Note: In high risk HPV negative patients (hrHPV) the vaccine virtually eliminated CIN associated with HPV types 16/18: 164-->2 per 10,000 for CIN2+ and 70-->0 per 10,000 for CIN3+. It also reduced CIN2+ caused by any cause, any HPV type, any random precancerous mutation from 287-->106 per 10,000.
...
"HPV16/18 negative
In those aged 15 to 26 years, vaccines reduce CIN2+ associated with HPV16/18 from 113 to 6 /10,000
...
Vaccines reduce any CIN2+ from 231 to 95/10,000"

>>>>> Note: In HPV16/18 negative patients the vaccine again virtually eliminated CIN2+ caused by HPV Type 16/18 from 113-->6 per 10,000. It also reduces the rate of CIN 2+ due to any cause from 231-->95 per 10,000.
...
"Adverse effects
The risk of serious adverse events is similar between control and HPV vaccines in women of all ages (669 versus 656/10,000 ... Mortality was 11/10,000 in control groups compared with 14/10,000 (9 to 22) with HPV vaccine (RR 1.29 [0.85 to 1.98]"

>>>>> Note: Serious adverse events and mortality were the same in the control and treated groups. IOW - the vaccine is not associated with serious adverse events or mortality.
...
"Pregnancy outcomes
Among those who became pregnant during the studies, we did not find an increased risk of miscarriage (1618 versus 1424/10,000, RR 0.88 (0.68 to 1.14), high certainty) or termination (931 versus 838/10,000 RR 0.90 (0.80 to 1.02), high certainty). The effects on congenital abnormalities and stillbirths are uncertain (RR 1.22 (0.88 to 1.69), moderate certainty and (RR 1.12 (0.68 to 1.83), moderate certainty, respectively)."

>>>>> Note: Miscarriage or termination of pregnancy had the same rate in the control and vaccinated groups meaning the vaccine is not associated with miscarriage. As noted they found that congenital abnormalities and stillbirths are uncertain (RR 1.22 (0.88 to 1.69), moderate certainty and (RR 1.12 (0.68 to 1.83), moderate certainty). If you note that both confidence ranges (0.88 to 1.69, and 0.68 to 1.83) extend from <1.0 (not associated) to >1.0 (associated). Under situations like this the best that can be said is that there is no association shown with the current data.
...
"Authors' conclusions
There is high-certainty evidence that HPV vaccines protect against cervical precancer in adolescent girls and young women aged 15 to 26.
The effect is higher for lesions associated with HPV16/18 than for lesions irrespective of HPV type.
...
We did not find an increased risk of serious adverse effects. Although the number of deaths is low overall, there were more deaths among women older than 25 years who received the vaccine. ... Increased risk of adverse pregnancy outcomes after HPV vaccination cannot be excluded, although the risk of miscarriage and termination are similar between trial arms. Long-term of follow-up is needed to monitor the impact on cervical cancer, occurrence of rare harms and pregnancy outcomes."

>>>>> Note: Those long term follow up studies searching for "rare harms" are even now being conducted as in the USA the FDA requires surveillance of the safety and efficacy of any vaccine after it is licensed for use in the US. This monitoring is ongoing year after year after year.
########################################
########################################
This is just more evidence to add to the huge stack of studies/evidence that the HPV vaccines are both effective and safe.
We have anti-cancer vaccines which can stop women from contracting cervical cancer and either suffering death or a hysterectomy.
.
It boggles the mind that there are folks who ignorantly campaign against these vaccines and for cervical cancer...
But, then again, there are morans who advocate for a Flat Earth and for Khemtrailz and Planet X so I guess there are folks that pig-ignorant.
.
Have your kids vaccinated against HPV. It is the sane thing to do.
.
Have fun.


R.
Ridicule is the only weapon which can be used against unintelligible propositions.
— Thomas Jefferson

Nothing is more terrible than to see ignorance in action.
— Johann Wolfgang von Goethe
Anonymous Coward
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05/09/2018 03:04 PM
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Re: HPV Vaccines Safe And Effective
Okay, your flat earth comment convinced me, how can I be associated with them?

What an awesome argument that was, especially when you threw in some local flair with the regional spelling of 'moran'.

I'm sold.
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n7t
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Anonymous Coward
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05/09/2018 03:08 PM
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Re: HPV Vaccines Safe And Effective
:Troll Thread:
Anonymous Coward
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Now OP, you know that GLPers will only accept health and medical information from known con artists like Mike Adams or Mercola.
Anonymous Coward
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Now OP, you know that GLPers will only accept health and medical information from known con artists like Mike Adams or Mercola.
 Quoting: Anonymous Coward 9205517


I’ll stand those two “con artists” toe-to-toe with any of your zombie doctors any day of the week.
Davos

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Re: HPV Vaccines Safe And Effective
Studies by the medical industry show the medical industry is safe and effective?

No way!

Hey op why not go and drink some roundup? monsanto swears its safe and hey, they would never lie would they?

Massage results, omit results, bury negative studies, pressure regulators, lobby government etc etc....

I'll let nature take its course, god knows best.
Anonymous Coward
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NOT A CHANCE!
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vaccineautism
For those who believe, no proof is necessary. For those who don't believe, no proof is possible. (Stuart Chase)

It's easier to fool people than to convince them that they have been fooled. (Mark Twain)
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vaccinemercury
For those who believe, no proof is necessary. For those who don't believe, no proof is possible. (Stuart Chase)

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vaccinebill
For those who believe, no proof is necessary. For those who don't believe, no proof is possible. (Stuart Chase)

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Nobody believes it. Go wash your mouth out with ass juice.
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derp
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this is a satire thread, right OP?
it has to be, because nobody here on glp could be that fucking moranic.
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vaccinemercury
 Quoting: Trained Noticer


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Nobody believes it. Go wash your mouth out with ass juice.
 Quoting: Ralph--a house dog


3fj
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Reality420  (OP)

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Re: HPV Vaccines Safe And Effective
I see the drooling anti-science, anti-vaccine, pro-disease, pro-cancer cretins have weighed in.
.
I'm impressed by their sober and analytical evaluation of this report. I was expecting the high school dropout anti-vaccine morans who are functionally illiterate, scientifically illiterate and innumerate to make completely fact-free anti-vaccine posts that essentially say - "You're a big poopy-head for saying good things about vaccines." </sarc>
.
Readers will note that all the anti-vaccine posts are merely emotional cries for a 'safe space' where there are no pro-science, pro-medicine posts. None of the posts contain any facts but that is to be expected.
.
I wonder if any of the antis is a Flat Earther or a Moon Hoaxie or a Khemtrailer?
.
It just goes to show you that parents should get their medical information from recognized experts and their physician rather than from the denizens of k00ky konspiracee websites and forums.

Have fun.


R.

Edited a typo - no space between "the" and "high school"

Last Edited by Reality420 on 05/09/2018 09:45 PM
Ridicule is the only weapon which can be used against unintelligible propositions.
— Thomas Jefferson

Nothing is more terrible than to see ignorance in action.
— Johann Wolfgang von Goethe
Reality420  (OP)

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05/09/2018 05:46 PM
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Re: HPV Vaccines Safe And Effective
Testing, testing, testing...

It seems I can't respond to posts on my thread for some reason... I've tried 2ce and both time the post did not show.
Ridicule is the only weapon which can be used against unintelligible propositions.
— Thomas Jefferson

Nothing is more terrible than to see ignorance in action.
— Johann Wolfgang von Goethe
Reality420  (OP)

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05/09/2018 05:50 PM
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Re: HPV Vaccines Safe And Effective
Third time's a charm? Changed some of the names in case they are disallowed names...
.
Let us take a look at one of the antis attempts at a technical response:
.
[link to www.godlikeproductions.com]
.
Note the source for Ms. Barney Fife's meme:
David I_ke and David Avocado W0lf3. It doesn't get more credible than those two. </sarc>
And, of course, the meme is mind-numbingly ignorant and shows Ms. Fife and David I_ke and pansy-assed NuAge David W0lfe are completely scientifically illiterate and innumerate.
Ms. Fife (and the others) apparently doesn't understand the difference between mass and concentration. Neither does Mike "The Death Ranger" Adams who came up with that "51,000" ppb.
.
Let us see if Ms. Fife can answer some questions and do some 4rth grade math for us and resolve a problem with her meme:
- Ms. Fife, which vaccines contain "mercury" and are they recommended in the USA for children?
Please tell us how much mercury a child gets under both these scenarios:
- one vaccination a year containing 50,000 ppb "mercury"
- one year of consuming 2 liters of water per day at the EPA max. of 2ppb
Please show your 4rth grade calculations...
- which contains more mercury and by what factor? (This involves 4rth grade fractions so you may not be up to it)
- if I were to take 12.5 liters of water at the EPA allowed 2ppb and evaporated it to 1/2 ml., what would its mercury concentration be?
.
Parents will now realize that getting your medical advice from random people on internet conspiracy sites is an exceptionally bad idea.
Just like getting financial advice from random internet k00ks is an exceptionally bad idea.

Have fun.


R.
Edited to add: Well, it finally took this post after I changed the names and didn't quote directly Ms. Barney Fife.
It's a konspiracee!!!!!11!!!! - or not.

Last Edited by Reality420 on 05/09/2018 05:52 PM
Ridicule is the only weapon which can be used against unintelligible propositions.
— Thomas Jefferson

Nothing is more terrible than to see ignorance in action.
— Johann Wolfgang von Goethe
Catseye

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05/09/2018 05:56 PM
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Re: HPV Vaccines Safe And Effective
Now OP, you know that GLPers will only accept health and medical information from known con artists like Mike Adams or Mercola.
 Quoting: Anonymous Coward 9205517



um, drug companies make more money the sicker you are

can you do math?
Forgive your enemies, it messes with their heads.

Thoughts create, mind them well.
Anonymous Coward
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05/09/2018 05:57 PM
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Re: HPV Vaccines Safe And Effective
HPV is a venereal disease.

I'm surprised parents aren't offended that the medical establishment automatically assumes that their daughters are a bunch of tramps in need of being vaccinated against an STD.
Anonymous Coward
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05/09/2018 06:05 PM
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Re: HPV Vaccines Safe And Effective
I see the drooling anti-science, anti-vaccine, pro-disease, pro-cancer cretins have weighed in.
.
I'm impressed by their sober and analytical evaluation of this report. I was expecting thehigh school dropout anti-vaccine morans who are functionally illiterate, scientifically illiterate and innumerate to make completely fact-free anti-vaccine posts that essentially say - "You're a big poopy-head for saying good things about vaccines." </sarc>
.
Readers will note that all the anti-vaccine posts are merely emotional cries for a 'safe space' where there are no pro-science, pro-medicine posts. None of the posts contain any facts but that is to be expected.
.
I wonder if any of the antis is a Flat Earther or a Moon Hoaxie or a Khemtrailer?
.
It just goes to show you that parents should get their medical information from recognized experts and their physician rather than from the denizens of k00ky konspiracee websites and forums.

Have fun.


R.
 Quoting: Reality420

My oldest girl is a medical professional trained in allopathic medicine. She got the shot. Got sick, did not take another one
and is moving into integrative medicine as soon as she can.
Reality420  (OP)

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05/09/2018 06:06 PM
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Re: HPV Vaccines Safe And Effective
Now OP, you know that GLPers will only accept health and medical information from known con artists like Mike Adams or Mercola.
 Quoting: Anonymous Coward 9205517


um, drug companies make more money the sicker you are

can you do math?
 Quoting: Catseye


Can you?
Why don't you show us by answering the questions I posed to Trained Noticer in this post:
[link to www.godlikeproductions.com]
.
I shall await your answers. Be sure to show your math...


R.
Ridicule is the only weapon which can be used against unintelligible propositions.
— Thomas Jefferson

Nothing is more terrible than to see ignorance in action.
— Johann Wolfgang von Goethe
Reality420  (OP)

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05/09/2018 06:13 PM
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Re: HPV Vaccines Safe And Effective
My oldest girl is a medical professional trained in allopathic medicine. She got the shot. Got sick, did not take another one
and is moving into integrative medicine as soon as she can.
 Quoting: Anonymous Coward 76558617


"allopathic" is a dead giveaway that you are an alt-med, anti-science advocate as that term was coined by homeopathetics who make a dishonest living selling magic water to gullible marks.
.
I'm sure your daughter is going "into integrative medicine" as soon as she can... with her family history.
.
What type of medical professional is she?
Chiroquack?
Acusticker?
Reiki prayer healer?
Energy medicine?
Light worker?
Crystal waver?


R.
Ridicule is the only weapon which can be used against unintelligible propositions.
— Thomas Jefferson

Nothing is more terrible than to see ignorance in action.
— Johann Wolfgang von Goethe
Reality420  (OP)

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05/09/2018 06:18 PM
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Re: HPV Vaccines Safe And Effective
HPV is a venereal disease.

I'm surprised parents aren't offended that the medical establishment automatically assumes that their daughters are a bunch of tramps in need of being vaccinated against an STD.
 Quoting: Anonymous Coward 76395149


HPV can be 'caught' by virgins, genius. All it takes is skin contact... not penetration. Your daughter may be pure as the driven snow and still catch HPV. Ever heard the term "petting"? Look it up. Kids are going to explore even if they stop short of the actual act of penetration as they've been trained.
.
She may also marry virginal and HPV free but what about her husband? How many married couples involve 2 absolutely virginal adults?
How about close to zero?
.
Time to wake up to the real world and not condemn your daughters to possible cervical cancer.


R.
Ridicule is the only weapon which can be used against unintelligible propositions.
— Thomas Jefferson

Nothing is more terrible than to see ignorance in action.
— Johann Wolfgang von Goethe
Anonymous Coward
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Panama
05/09/2018 06:19 PM
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Re: HPV Vaccines Safe And Effective
My oldest girl is a medical professional trained in allopathic medicine. She got the shot. Got sick, did not take another one
and is moving into integrative medicine as soon as she can.
 Quoting: Anonymous Coward 76558617


"allopathic" is a dead giveaway that you are an alt-med, anti-science advocate as that term was coined by homeopathetics who make a dishonest living selling magic water to gullible marks.
.
I'm sure your daughter is going "into integrative medicine" as soon as she can... with her family history.
.
What type of medical professional is she?
Chiroquack?
Acusticker?
Reiki prayer healer?
Energy medicine?
Light worker?
Crystal waver?


R.
 Quoting: Reality420


You're making assumptions. I think the post was clear enough. Her daughter was trained in allopathic medicine, but switched over to integrative medicine after personally experiencing a bad reaction to allopathic medicine.
Anonymous Coward
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05/09/2018 06:24 PM
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Re: HPV Vaccines Safe And Effective
My oldest girl is a medical professional trained in allopathic medicine. She got the shot. Got sick, did not take another one
and is moving into integrative medicine as soon as she can.
 Quoting: Anonymous Coward 76558617


"allopathic" is a dead giveaway that you are an alt-med, anti-science advocate as that term was coined by homeopathetics who make a dishonest living selling magic water to gullible marks.
.
I'm sure your daughter is going "into integrative medicine" as soon as she can... with her family history.
.
What type of medical professional is she?
Chiroquack?
Acusticker?
Reiki prayer healer?
Energy medicine?
Light worker?
Crystal waver?


R.
 Quoting: Reality420


Wrong. Don't quit your day job for a psychic job. There is a place for allopathic medicine, such as crisis medicine and once stable and if allopathic doesn't give telief, some complementary, integrative medicine can help. No one but you mentioned homeopathic treatments. Integrative medicine is just that, allopathic and alternative treatments such as supplements (what many drugs are based on) and massage etc. My kids had the common shots. That you are trying to Misdirect from my oldest having a reaction to this shot and chose to ignore that and focus on one word, should that tell me you work for a drug company?
Anonymous Coward
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05/09/2018 06:28 PM
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Re: HPV Vaccines Safe And Effective
My oldest girl is a medical professional trained in allopathic medicine. She got the shot. Got sick, did not take another one
and is moving into integrative medicine as soon as she can.
 Quoting: Anonymous Coward 76558617


"allopathic" is a dead giveaway that you are an alt-med, anti-science advocate as that term was coined by homeopathetics who make a dishonest living selling magic water to gullible marks.
.
I'm sure your daughter is going "into integrative medicine" as soon as she can... with her family history.
.
What type of medical professional is she?
Chiroquack?
Acusticker?
Reiki prayer healer?
Energy medicine?
Light worker?
Crystal waver?


R.
 Quoting: Reality420


Wrong. Don't quit your day job for a psychic job. There is a place for allopathic medicine, such as crisis medicine and once stable and if allopathic doesn't give telief, some complementary, integrative medicine can help. No one but you mentioned homeopathic treatments. Integrative medicine is just that, allopathic and alternative treatments such as supplements (what many drugs are based on) and massage etc. My kids had the common shots. That you are trying to Misdirect from my oldest having a reaction to this shot and chose to ignore that and focus on one word, should that tell me you work for a drug company?
 Quoting: Anonymous Coward 76558617


Her degree is in allopathic medicine. Working in the hospital treating Chronically Ill patients had given her a new perspective. Medicine is not the "settled science" of the Alford global warming and thank God it is not.
Cheers
Anonymous Coward
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05/09/2018 06:40 PM
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Re: HPV Vaccines Safe And Effective
Yeah sure...

Bbc is MSM horsesh!t bought and paid for by big toxic pharma.
die you good thing
User ID: 76561917
Australia
05/09/2018 06:50 PM
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Re: HPV Vaccines Safe And Effective
Ulterior motives





GLP