Covid19/2021-22 OMICRON/ VIRUS "IHU" FRANCE:P13310/NEWEST VIRUS: "NEOCOV" HIGH INFECTION RATE+1 IN 3 DIE !?! P13315

Your Brain on Covid - Long Term Implications - Synaptic Infection - Neurological Disorders - Universal Permanant Alterations in Those Who “Recovered”

Virus infection causes alterations in expression of synaptic regulatory genes combined with changes in cognitive and emotional behaviors.

Viral infections of the CNS that injure or destroy specific populations of brain cells are frequently associated with behavioral disturbances. These events occur either directly due to virus replication or indirectly as a result of the host immune response against the infectious agent. Neurotropic viruses can also persist in the CNS and, in the absence of cell destruction or inflammation, cause defects in goal-oriented behavior. Therefore, viruses may contribute to human CNS disorders whose etiology remains elusive. The finding of virally mediated impairment in neuronal function in the absence of cell destruction raises the possibility that noncytolytic viruses that persistently infect neurons may contribute to many human CNS disorders whose etiology is unknown.

SARS-CoV-2 can also infect the brain by migrating from the general circulation to the cerebral microcirculation via endothelial cells which express ACE2[5].In a recent case study published by Poyiadji et al.[25], they described an acute hemorrhagic necrotizing encephalopathy that was directly attributed to SARS-CoV-2 infection and the concurrent cytokine storm induced upon infection[25,26]. Beyond isolated cases of overt severe neurological pathologies, 45% of severe cases exhibited neurologic symptoms[3], increasing the likelihood that potential complications arising from severe SARS-CoV-2 infections may have a strong neurologic component that has yet to be described and characterized. Human coronavirus OC43 has been demonstrated to be transmitted in mice both passive diffusion of released viral particles and axonal transport[27].

[link to nnjournal.net (secure)]

The current global pandemic outbreak of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is known for its viral tropism to the lungs, which in severe cases can lead to the fatal respiratory failure of patients who have contracted the disease. SARS-CoV-2 and SARS-CoV viruses have a 70%-80% homology and both enter the body through the same receptor, angiotensin converting enzyme 2 (ACE2)[1].

In addition to their genetic homology, the pathology that the two viruses exhibit in the clinic are highly similar[2]. In a recent report from Wuhan, China, Mao and colleagues showed that in addition to respiratory symptoms including pneumonia and acute respiratory distress syndrome (ARDS), out of 214 hospitalized COVID-19 patients 78 (36.4%) showed neurological manifestations such as cerebrovascular diseases (5.7%), impaired consciousness (14.8%), and skeletal muscle injury (19.3%)[3]. Six percent of COVID-19 patients have been reported to show symptoms of stroke and 15% were reported to show encephalopathy[4]. A number of symptoms such as dizziness, headache, loss of taste and smell, impaired consciousness, seizures, and nerve pain suggest a neurological connection to this viral infection.


Neuromechanisms of SARS-CoV-2: A Review

[link to www.frontiersin.org (secure)]

If Texas hospitalization numbers aren't at least 500 lower 1 week from today than what they are now, I'll put a dunce cap on my avatar for a month.

I wish I was as sure as you. My oldest son still lives in Texas. He manages a heating and ac parts house. They were considered essential from the beginning. I don't have all the details, but he and most of his staff are now home in isolation. A couple of people are positive and sick. I'll talk to him later to get the rest of the story.

I wish I was as sure as you. My oldest son still lives in Texas. He manages a heating and ac parts house. They were considered essential from the beginning. I don't have all the details, but he and most of his staff are now home in isolation. A couple of people are positive and sick. I'll talk to him later to get the rest of the story.

Peaking doesn't mean the virus went away... I'm just saying I think that from here on out it's going to be downward trends instead of upward.

We're still probably gonna be at 9-10k for a few days, maybe if we're lucky down to 6k a week from now.

That's still a lot of people getting sick.

Ok..3rd time's a charm they say. Down and dirty , so this one won't go away. The South Plains and the rest of the western counties, are so sparsely populated compared to the large cities. Even Lubbock, the biggest city on the SP, isn't on their scale.

Up until recently, the numbers have been in the single digits for most of the counties. That's just the confirmed cases. Single digits. I think they are still peaking out there. Lubbock is the major hub for anything shopping, entertainment, doctors, etc. With the shutdown, the outliers didn't get exposed as much. unless, like my son, you work there. Besides, it's a planned event for the far counties to go to Lubbock, Amarillo, Hobbs, or Clovis. When you have to drive an hour or more, you tend to plan it out.

Ok, rant off, before this post disappears on me, too.

Hospitals get testing priority, I highly doubt that they are lacking on testing of admitted persons with COVID symptoms. Perhaps Halo could chime in on this.

Hospitalization numbers in Texas have been essentially flat for 5 days, that's not an anomoly that's a trend. Positivity rate has been flat for about the same time period.

I feel confident enough that Texas has peaked, I'll lay out my "Dunce Cap" wager once more.

If Texas hospitalization numbers aren't at least 500 lower 1 week from today than what they are now, I'll put a dunce cap on my avatar for a month.

I don't believe for one second Texas, or any other state, has "peaked." Eventually, you just max out your testing capacity, at which point the numbers flatline, mimicking a "peak."

Sorry, Wordsie, I know you still hold out hope for a happy ending, but this is "The Titanic" we're living, not "The Love Boat."

You probably want to take that back before to many people read that.

My nephew in Houston 37yr old, got it from his job at the hospital. He quarantined for 35 days. Never got any respiratory symptoms, but got the fever and all over horrible feeling and exhaustion. He started to feel better after 10 days but continues to test positive every week. He was just hospitalized because he was falling when walking and having seizures. I am so worried for him right now. Labs came back good and CT is clear, we are waiting on EEG and MRI to come back.