Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus

This is the reason Americans on cruise ship infected show no signs of death or struggle..... only the Chinese vaccinated with SARS vaccine


OP IS RIGHT ON MONEY

SARS Vaccine combined with Corona Virus is a death sentence otherwise it’s the flu

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this!!!!!!

What is the difference with SARS-CoV and MERS-CoV -

"Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus"


[link to www.frontiersin.org (secure)]

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Middle East respiratory syndrome (MERS) is a deadly viral respiratory disease caused by MERS-coronavirus (MERS-CoV) infection. To date, there is no specific treatment proven effective against this viral disease. In addition, no vaccine has been licensed to prevent MERS-CoV infection thus far. Therefore, our current review focuses on the most recent studies in search of an effective MERS vaccine. Overall, vaccine candidates against MERS-CoV are mainly based upon the viral spike (S) protein, due to its vital role in the viral infectivity, although several studies focused on other viral proteins such as the nucleocapsid (N) protein, envelope (E) protein, and non-structural protein 16 (NSP16) have also been reported. In general, the potential vaccine candidates can be classified into six types: viral vector-based vaccine, DNA vaccine, subunit vaccine, nanoparticle-based vaccine, inactivated-whole virus vaccine and live-attenuated vaccine, which are discussed in detail. Besides, the immune responses and potential antibody dependent enhancement of MERS-CoV infection are extensively reviewed. In addition, animal models used to study MERS-CoV and evaluate the vaccine candidates are discussed intensively.

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So, we now have a category C bio-weapon if MERS-CoV is this classification - so is SARS-CoV

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Potential Antibody Dependent Enhancement (ADE) of Mers-CoV Infection

Antibody dependent enhancement (ADE) is a condition whereby non-neutralizing antibodies are produced following an infection or a vaccination, which enhance the infectivity of the subsequent infection (Kuzmina et al., 2018). ADE of viral infections have been reported for dengue virus, human immunodeficiency virus, influenza virus, other alpha and flaviviruses, SARS-CoV, and Ebola virus (Dutry et al., 2011; Kuzmina et al., 2018). Thus, ADE is a critical issue that should be considered seriously in designing a MERS-CoV vaccine.

Attributed to the taxonomic and structural similarities between SARS-CoV and MERS-CoV, the processes involved in development of new vaccines against these two viruses, to a large extent, are similar. Vaccine candidates against SARS-CoV were initially developed based on the full-length S protein. However, these vaccines were later demonstrated to induce non-neutralizing antibodies which did not prevent MERS-CoV infection, and the immunized animals were not protected from the viral challenge instead they experienced adverse effects like enhanced hepatitis, increased morbidity, and stronger inflammatory responses (Weingartl et al., 2004; Czub et al., 2005). Many potential vaccines against MERS-CoV were also mainly focused on the same full-length S protein, raising a safety concern on the practical application of these vaccines (Du et al., 2016b).

To date, no ADE has been observed in MERS-CoV. Indeed, the ADE of SARS-CoV infection in human cells was only discovered 8 years after the virus was first identified in 2003 (Yip et al., 2011). Jaume et al. (2012) demonstrated that non-neutralizing antibodies induced by the full-length S protein of SARS-CoV facilitated the viral entry into host cells via a FcγR-dependent pathway. Our understanding about MERS-CoV is relatively lesser compared to SARS-CoV, mainly due to the fact that the former was discovered less than 7 years, thus it is unsurprising that the ADE of MERS-CoV has yet to be reported (Du et al., 2016b). Nevertheless, by employing appropriate strategies and methods, the ADE of MERS-CoV infection could be revealed in the future.

Two approaches have been suggested to mitigate the adverse effects of ADE. The first approach involves shielding the non-neutralizing epitopes of the S proteins by glycosylation, whereas the second approach, namely immunofocusing, aims to direct the adaptive immune responses to target only the critical neutralizing epitope to elicit a more robust protective immunity (Du et al., 2016a; Okba et al., 2017). A supporting evidence for the latter is that a MERS-CoV vaccine candidate based on a shorter S1 domain induced slightly stronger neutralizing activity than that based on the full-length S protein. In addition, a vaccine candidate based on the even shorter RBD induced the highest neutralizing immune responses (Okba et al., 2017).

Current Mers-CoV Vaccine Platforms

As of now, SARS-CoV and MERS-CoV are the only coronaviruses known to cause severe diseases in human. Development of SARS vaccines was mainly focused on the S protein of SARS-CoV (Bukreyev et al., 2004; Weingartl et al., 2004; Yang et al., 2004; Czub et al., 2005; Kam et al., 2007; Lin et al., 2007; Fett et al., 2013). To date, no vaccine has been licensed to prevent MERS-CoV infection. Although several vaccine candidates are currently in clinical trials, many still remained in the pre-clinical stage. Current approaches for the development of MERS-CoV vaccines are mostly referred to the methods used for the development of SARS-CoV vaccines during the past two decades, which include: viral vector-based vaccine, DNA vaccine, subunit vaccine, virus-like particles (VLPs)-based vaccine, inactivated whole-virus (IWV) vaccine and live attenuated vaccine.

ITS IN THE DETAILS. SARS VACCINE TOGETHER WITH CORONA VIRUS IS CAUSING EXTREME REACTION IN THE LUNGS AND ALMOST CERTAIN DEATH

This is the reason Americans on cruise ship infected show no signs of death or struggle..... only the Chinese vaccinated with SARS vaccine

Assume everyone has or will have Corona virus in the next year

Can another vaccine be created like SARS vaccine to cause a massive violent possibly terminal response by a human's immune system?


Chinese that have taken SARS vaccine die now what vaccine will be introduced in the future? Who will die next time?

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This is an important thread. Thank you op

People are resistant to this information / theory. But it explains what we are seeing perfectly.

The virus is spreading, but the deadly illness for the most part is not.

dont let this coronavirus be excuse for more Vaccines!!!!!!

today its the Chinese who took SARS vaccine in the future it could be all of us with a new vaccine introdcution

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Wrong

[link to en.wikipedia.org (secure)]



Wrong

Thread: HOLY SHITBALLS!!!! CHYNA TRYING TO INFILTRATE AND INFLUENCE STATE GOVERNORS!!!! WoW!!! POMPEO SPILLS THE BEANS!!! (VIDEO)

[link to jameslyonsweiler.com (secure)]

SARS Vaccine combined with Corona Virus is causing all the death in China

Only country in world besides China possibly N Korea our the only countries to vaccinate for SARS

LINK above has the details

Cases spreading around the world but only those with SARS vaccine our dead
Page 1 2 3

OP Your over target

The Entire Vaccine Industry in China is a Farce

Has been for decades BLACK MARKET VACCINES


How a New Law Turned China’s Vaccine Industry Upside-Down

China is trying to inoculate itself against future faulty vaccine scandals with strict new legislation. But the changes have led to complications.

[link to www.sixthtone.com]


would bet my bottom dollar...

for the right amount of money you could buy a CV vaccine through out China

same damn thing happened in July 2019 when the Swine flu caused 1000's of pigs to be culled

China is Bootleg Vaccine Central

Thanks for link. May support the theory.

My argument is based around there has been nothing in place to prevent any vaccine with known advesr side effects from being sold in china.

None. At. All.

The new laws came in to effect 1 Dec 2019.

Coronebola detected prior.

This may have been a dump on the pop in anticipation of profit loss via Non Gov vaccine producers.

New laws were announced April 2019?

Last Edited by Baldrick on 02/15/2020 12:45 AM

Looks like the same thing is happening with the covid vaccines.