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Found some interesting work on the creation of pseudoviruses using HIV and SARS coronavirus

 
Virion Alpha
User ID: 78017652
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02/09/2020 06:54 PM
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Found some interesting work on the creation of pseudoviruses using HIV and SARS coronavirus
The big gripe that molecular geneticists had about the supposed 4 inserts from the HIV geneome into the Wuhan virus genome was that the 4 nucleotide sequences were discontinuous

Meaning that the 4 chains of amino acids were spread out in the virus genome

They were about this long-----> taggcta

Each supposed " insert " was spread out from the others, and this fact of separation was used by the scientists that claimed that this is proof that the science done by the Indian scientists was bad, because when you normally look for evidence of transgenes ( inserted genetic material ), you look for the evidence of a pShuttle, which in turn will be attached to a large chain of amino acids

( A pShuttle is a recombinant plasmid ( An engineered tool used for gene insertions, " p " means " plasmid " )
Normally, in order to really be considered evidence of a gene insertion, and since there are practically countless plasmids created in endless labs, you have to look for the genes that were inserted WITH the pShuttle

So you look for a long chain like this:

gatgctagatgtttaagaagcctagttccagattaccagtgatgctagatgtttaagaagc​ctagttccagattaccagtgatgctagatgtttaagaagcctagttccagattaccagtga​tgctagatgtttaagaagcctagttccagattaccagtgatgctagatgtttaagaagcct​agttccagattaccagtgatgctagatgtttaagaagcctagttccagattaccagt

Then the pShuttle chains would normally be here:

gatgctagatgtttaagaagcctagttccagattaccagtgatgctagatgtttaag​aagcctagttccagattaccagtgatgctagatgtttaagaagcctagttccagattacca​gtgatgctagatgtttaagaagcctagttccagattaccagtgatgctagatgtttaagaa​gcctagttccagattaccagtgatgctagatgtttaagaagcctagttccagattacca​gt

Those red chains bind the insert into the rest of the genome ( From one organism into another )





So here's the problem with the claiming that the indian scientists were wrong

When the actual S-protein of the Wuhan virus folds, it just so happens that the 4 " HIV inserts " happen to line up exactly at the spike tip of the S-protein that the Virus uses to bind to ACE2 which is then used to gain entry into the cells


This combining of HIV and Coronavirus genomes is discussed in this following paper identifying novel ACE2 inhibitors ( Things that block the virus from using the body's own ACE2 peptide to gain entry to cells )


[link to www.ncbi.nlm.nih.gov (secure)]



siren2siren2siren2
Anonymous Coward (OP)
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02/09/2020 07:12 PM
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Re: Found some interesting work on the creation of pseudoviruses using HIV and SARS coronavirus
should I not bother posting this kind of stuff ?

not sure if you guys actually have any interest in it
acinnc
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02/09/2020 07:28 PM
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Re: Found some interesting work on the creation of pseudoviruses using HIV and SARS coronavirus
It's good but for most of us it's above our paygrade
Anonymous Coward (OP)
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02/10/2020 02:50 AM
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Re: Found some interesting work on the creation of pseudoviruses using HIV and SARS coronavirus
bump
Nexus-9

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02/10/2020 02:55 AM
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Re: Found some interesting work on the creation of pseudoviruses using HIV and SARS coronavirus
SCIENCE!
"Fiery the Angels rose, & as they rose deep thunder roll'd
Around their shores: indignant burning with the fires of Orc" - William Blake, America a Prophecy
(...also misquoted in Blade Runner by Roy Batty)

"Tempus est optimus iudex" - "Time is the best judge"

"The very word "'secrecy'" is repugnant in a free and open society; and we are as a people inherently and historically opposed to secret societies, to secret oaths and to secret proceedings." - John F. Kennedy, New York City, April 27, 1961
Nexus-9

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02/10/2020 02:56 AM
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Re: Found some interesting work on the creation of pseudoviruses using HIV and SARS coronavirus
should I not bother posting this kind of stuff ?

not sure if you guys actually have any interest in it
 Quoting: Anonymous Coward 78017652


:star2:
"Fiery the Angels rose, & as they rose deep thunder roll'd
Around their shores: indignant burning with the fires of Orc" - William Blake, America a Prophecy
(...also misquoted in Blade Runner by Roy Batty)

"Tempus est optimus iudex" - "Time is the best judge"

"The very word "'secrecy'" is repugnant in a free and open society; and we are as a people inherently and historically opposed to secret societies, to secret oaths and to secret proceedings." - John F. Kennedy, New York City, April 27, 1961
Anonymous Coward
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02/10/2020 03:31 AM
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Re: Found some interesting work on the creation of pseudoviruses using HIV and SARS coronavirus
bump
 Quoting: Anonymous Coward 78017652


your cells have iodide receptors in each cell

a couple drops of potassium iodide under your tounge will trigger cell death for the virus
Anonymous Coward
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02/10/2020 03:46 AM
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Re: Found some interesting work on the creation of pseudoviruses using HIV and SARS coronavirus
bumpfor SCIENCE.
Anonymous Coward
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02/10/2020 03:47 AM
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Re: Found some interesting work on the creation of pseudoviruses using HIV and SARS coronavirus
Thanks for posting this ... I find it very interesting.





GLP