Who has data on the antibody titers of the coronavirus patients ? | |
Anonymous Coward (OP) User ID: 78017652 United States 03/07/2020 02:55 PM Report Abusive Post Report Copyright Violation | |
Anonymous Coward (OP) User ID: 78017652 United States 03/07/2020 03:10 PM Report Abusive Post Report Copyright Violation | I know that for the first SARS, that AB levels were still detectable at 6 years, but only in 2 patients out of 23 as per this paper ( journal of immunology ): [link to www.jimmunol.org (secure)] |
Anonymous Coward (OP) User ID: 78017652 United States 03/07/2020 03:25 PM Report Abusive Post Report Copyright Violation | Apparently, the virus may also hide in the epithelial cells of the digestive tract ( In addition to the brain stem ) You can see from this paper that patients' anal swabs tested positive while throat swabs did not This was after the infection had subsided The virus is still present, but only in certain areas of the body, so if they are only doing throat swabs to confirm the virus isn't present in the body of the recovered patient....it will give a false negative unless they do the anal swab " Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes " [link to www.tandfonline.com (secure)] |
Fluffy Pancakes
User ID: 51775590 United States 03/07/2020 03:39 PM Report Abusive Post Report Copyright Violation | OK....this is slightly disturbing( Not about AB tho ) Quoting: Anonymous Coward 78017652 Apparently, the virus may also hide in the epithelial cells of the digestive tract ( In addition to the brain stem ) You can see from this paper that patients' anal swabs tested positive while throat swabs did not This was after the infection had subsided The virus is still present, but only in certain areas of the body, so if they are only doing throat swabs to confirm the virus isn't present in the body of the recovered patient....it will give a false negative unless they do the anal swab " Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes " [link to www.tandfonline.com (secure)] Well that sucks. So if they swab the throat and it's neg, that doesn't mean the person is yet over the virus. Copy. I didn't see that they tested infectivity capacity of the found virus in recovered people?Recovered by whatever determination- Early on I heard it was negative swab and asymptomatic for 14 days. If the antibodies are indicating a person has been exposed, it isn't yet clear whether or not that person is still an active shedder. Also, on pre-symptomatic spreading, it really acts like a retrovirus. And I haven't seen any papers yet looking at that with SarsCov2. I have too many unanswered questions about this. Things are bad enough, there is no need to make anything up. ~Fluffy "Never interrupt an enemy in the process of destroying himself." Quercitin and zinc...Get it. Take it. Visit howbad.info...If you took the shot, for sure. |
Anonymous Coward (OP) User ID: 78017652 United States 03/07/2020 03:46 PM Report Abusive Post Report Copyright Violation | OK....this is slightly disturbing( Not about AB tho ) Quoting: Anonymous Coward 78017652 Apparently, the virus may also hide in the epithelial cells of the digestive tract ( In addition to the brain stem ) You can see from this paper that patients' anal swabs tested positive while throat swabs did not This was after the infection had subsided The virus is still present, but only in certain areas of the body, so if they are only doing throat swabs to confirm the virus isn't present in the body of the recovered patient....it will give a false negative unless they do the anal swab " Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes " [link to www.tandfonline.com (secure)] Well that sucks. So if they swab the throat and it's neg, that doesn't mean the person is yet over the virus. Copy. I didn't see that they tested infectivity capacity of the found virus in recovered people?Recovered by whatever determination- Early on I heard it was negative swab and asymptomatic for 14 days. If the antibodies are indicating a person has been exposed, it isn't yet clear whether or not that person is still an active shedder. Also, on pre-symptomatic spreading, it really acts like a retrovirus. And I haven't seen any papers yet looking at that with SarsCov2. I have too many unanswered questions about this. The thing that gets me, was that the 14 day quarantine period was originally determined by taking the average of a bunch of cases, for the length of the asymptomatic period, when in fact it should have been over double that, literally a month Like with SARS, you were asked to spend one week in isolation at home during convalescent recovery, yet some patients were still shedding in fluids at 6 weeks after the clinical period They weren't considered highly infectious because the virus had already undergone a mutation in the spike protein that lowered it's binding affinity for ACE2, and that combined with low viral load, made it hard to catch from those no longer battling the infection but this virus.....totally different apparently..... Really just frightful, the ineptitude I'm seeing |
Fluffy Pancakes
User ID: 51775590 United States 03/07/2020 04:15 PM Report Abusive Post Report Copyright Violation | The level of severity regarding needing hospitalization hanging around 20% is really an issue. Things are bad enough, there is no need to make anything up. ~Fluffy "Never interrupt an enemy in the process of destroying himself." Quercitin and zinc...Get it. Take it. Visit howbad.info...If you took the shot, for sure. |
Anonymous Coward (OP) User ID: 78017652 United States 03/07/2020 04:20 PM Report Abusive Post Report Copyright Violation | It's almost as if they've completely given up containment. And that's really bad even if it does become endemic world wide. Quoting: Fluffy Pancakes The level of severity regarding needing hospitalization hanging around 20% is really an issue. The way it's perfectly aerosolized means it will not be able to be quarantined, would take BSL-4 protocols ....so impossible at this point The severity of infection, yeah, frightening. People are also apparently having trouble grasping that when hospitals are overrun, deaths will double, so all those mortality rates and CFR's are going go UP.......that people do not grasp this ....is highly disturbing |
Fluffy Pancakes
User ID: 51775590 United States 03/07/2020 04:38 PM Report Abusive Post Report Copyright Violation | It's almost as if they've completely given up containment. And that's really bad even if it does become endemic world wide. Quoting: Fluffy Pancakes The level of severity regarding needing hospitalization hanging around 20% is really an issue. The way it's perfectly aerosolized means it will not be able to be quarantined, would take BSL-4 protocols ....so impossible at this point The severity of infection, yeah, frightening. People are also apparently having trouble grasping that when hospitals are overrun, deaths will double, so all those mortality rates and CFR's are going go UP.......that people do not grasp this ....is highly disturbing But there is still mitigation that could help so as not to collapse the hospitals and increase the death rate. Pretty common sense ones, really. I get that there isn't any putting it back in the bottle and believe it will be endemic to the world, but if we can slow transmission through behavior changes, we may get a little handle on it. You don't think so? Things are bad enough, there is no need to make anything up. ~Fluffy "Never interrupt an enemy in the process of destroying himself." Quercitin and zinc...Get it. Take it. Visit howbad.info...If you took the shot, for sure. |
Anonymous Coward (OP) User ID: 78017652 United States 03/07/2020 04:42 PM Report Abusive Post Report Copyright Violation | It's almost as if they've completely given up containment. And that's really bad even if it does become endemic world wide. Quoting: Fluffy Pancakes The level of severity regarding needing hospitalization hanging around 20% is really an issue. The way it's perfectly aerosolized means it will not be able to be quarantined, would take BSL-4 protocols ....so impossible at this point The severity of infection, yeah, frightening. People are also apparently having trouble grasping that when hospitals are overrun, deaths will double, so all those mortality rates and CFR's are going go UP.......that people do not grasp this ....is highly disturbing But there is still mitigation that could help so as not to collapse the hospitals and increase the death rate. Pretty common sense ones, really. I get that there isn't any putting it back in the bottle and believe it will be endemic to the world, but if we can slow transmission through behavior changes, we may get a little handle on it. You don't think so? I think it's possible, but I also think people are SEVERELY underestimating the transmissible nature of this virus due to how it interacts with lung surfactant in the alveoli So it's going to take a lot of mistakes to come to this realization unfortunately.... |
Anonymous Coward (OP) User ID: 78017652 United States 03/07/2020 04:47 PM Report Abusive Post Report Copyright Violation | See, aerosolizing of a virus isn't something that just happens because the infection is in the lower respiratory airways where aerosol particles are generated It has to do with the physicochemical properties of the M ( membrane ) protein of that specific virus and how it interacts with the lung surfactants many viruses won't aerosolize because of their physicochemical properties won't allow them to be taken into micelles generated by lung surfactant in the alveoli ( It's it's impossible for them to be aerosolized ) This one on the other hand ....couldn't aerosolize better |
Anonymous Coward User ID: 73106316 United States 03/07/2020 05:01 PM Report Abusive Post Report Copyright Violation | |
Fluffy Pancakes
User ID: 51775590 United States 03/07/2020 05:51 PM Report Abusive Post Report Copyright Violation | See, aerosolizing of a virus isn't something that just happens because the infection is in the lower respiratory airways where aerosol particles are generated Quoting: Anonymous Coward 78017652 It has to do with the physicochemical properties of the M ( membrane ) protein of that specific virus and how it interacts with the lung surfactants many viruses won't aerosolize because of their physicochemical properties won't allow them to be taken into micelles generated by lung surfactant in the alveoli ( It's it's impossible for them to be aerosolized ) This one on the other hand ....couldn't aerosolize better I'm cognizant of the fact that this travels through air handlers pretty efficiently. Ala Diamond Princess. Also that it stays on surfaces quite readily as well. But if we could all basically self quarantine for a month or so, while many may already have it, it should seriously slow down the infection rate. Obviously, reality is going to take umbrage with the idea that even at this point, the best thing to do is think everyone including yourself may have this and treat everyone and yourself with respect and try to not spread this through not going anywhere you absolutely do NOT have to go and wear a mask and eye protection if you can get eye protection. Even a bandana with some antiviral essential oils would help. Man. I just see that we already have very extensive and certain economic fall out just from China, but if we allow our hospitals to become completely overrun, we are going to be in even more serious danger as far as loss of civility, destruction of economy and devastating increases in deaths. Things are bad enough, there is no need to make anything up. ~Fluffy "Never interrupt an enemy in the process of destroying himself." Quercitin and zinc...Get it. Take it. Visit howbad.info...If you took the shot, for sure. |
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