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TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!

 
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TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Hydroxychloroquine: Help Is On The Way!

Kevin McCullough
Posted: March 29, 2020 11:10 AM


Over the past couple of days I’ve lost literal count of how many people have written to me asking about the clinical trials in New York State regarding the use of Hydroxychloroquine.

The trials began last Tuesday.

In this column’s space and much more liberally on my Twitter feed I have attempted to stay up-to-date on the rapidly developing reports of the effectiveness of Hydroxychloroquine. I’ve also dedicated a considerable percentage of my radio show over the last two weeks highlighting these developments.

It’s strange that I should need to.

Before the drug was mentioned by President Trump there had been a robust interest in looking at the replicated results from China, India, South Korea and France. Sadly, American medical authorities didn’t really give any credence to the claims until the controlled study in southern France, which returned a one in 10,000 chance that the results were anecdotal or in anyway not possible to replicate repeatedly.

Dr. Fauci dragged his feet even as that study was becoming public. Then the president mentioned it, and all of a sudden it became a political issue.

It should not be.

The willingness by anyone of either political party to weaponize an actual solution or series of solutions to COVID-19 is utterly inhuman.

And as the good news is coming in there is a greater reason for hope!

Here are just a handful of new developments from the last few days and hours.

1. Dr. Fauci when asked if he would use the Hydroxychloroquine cocktail, answered with resounding affirmation. (Simply because he had asked for better clinical evidence previously did not mean he was unaware of what the data was already showing).

2. France reversed its previous ban on the drug. When the highly esteemed Dr. Didier Raoult released his first survey’s findings the French medical authorities were resistant. As he released an even larger study, with more patients and improved results from his initial study, the French public health officials had no choice but to give guidance as to its use.

3. India’s public health guidance granted affirmation for physicians and front line medical workers to begin taking it as a preventative. This use was the very suggestion I recommended as first steps in this column a week ago. Since our own CDC has cited its prophylactic benefits our doctors and front line medical personnel should be taking it now.

4. Given the increased acceptance here in the states not one, but as many as seven different pharmaceutical companies have agreed to mass produce as much as 250 million doses by mid-April. Given Dr. Raoult’s guidance in both of his studies this would give the globe enough inventory to cure 46,000,000 cases. Presently we have not yet hit one million cases worldwide. Notably Bayer, Novartis and Teva Pharm stepped up, pledging to donate several million doses right out of the shoot.

5. Doctors began prescribing off-label use and in doing so are replicating the clinical results in remarkable fashion. One doctor in Monroe, New York has treated in excess of 700 patients. As of this writing he’s lost zero patients to death, zero to intubation, and only two to hospitalization. Another doctor in New York City has treated in excess of 100 patients with zero deaths.

CONTINUED AT:
[link to townhall.com (secure)]

Last Edited by Doc Savage on 03/29/2020 04:46 PM
Pilgrim001

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03/29/2020 04:56 PM

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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Where can I buy some for prophylactic use?
I don't have the time or the crayons to explain this to you.



Slake Blake
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03/29/2020 04:58 PM
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Great news! 5*
beeches

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03/29/2020 04:59 PM

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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Where can I buy some for prophylactic use?
 Quoting: Pilgrim001


online maybe? never tried to get any drug that way

meanwhile, quinine water and finding out if anyone you know enough to ask

is on Plaquenil
Liberalism is totalitarianism with a human face – Thomas Sowell
CK Dexter Haven

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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
It is suspicious they're trying to discredit this treatment out of hand when there seems to be substantial evidence it may be very helpful.

Twitter going as far as to censor posts on it.
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
From the article:

The Democrats, the media, and people who despise the president don’t want these trials to succeed. Three Democrat governors have gone so far as to ban the use of the drug cocktail. And one has even threatened action against doctors who prescribe it. Which is an odd juxtaposition for the days we live in. It appears that the President cares more about their constituents in their states than their own governors do.

[link to townhall.com (secure)]
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Where can I buy some for prophylactic use?
 Quoting: Pilgrim001


My doctor refused.

Even for a close family member battling stage 4 cancer, and my asthmatic child.

California...
LoneStarRisingModerator
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Where can I buy some for prophylactic use?
 Quoting: Pilgrim001

Not for prophylactic use, but you can get it here if you test positive for COVID-19.

Thread: Telehealth company is already prescribing the hydroxychloroquine and azithromycin drug combination for COVID-19 patients nationwide
LoneStarRising
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Yay!

It can have serious side effects so be forewarned. Not as serious as dying of virus though.
CK Dexter Haven

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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Apparently they have a different drug in mind to become the standard treatment?

:lmmoney:
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Another thing....this virus appears to live in you forever, like chicken pox or cold sores. Dont stop being vigilant in protecting yourself and staying healthy.
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Why would the demo rats want to be successful when they defended and promoted this crisis?
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Where can I buy some for prophylactic use?
 Quoting: Pilgrim001


I've bought it over the counter in Mexico, but you have to have a doctor's prescription to get it here in the U.S.

I priced it out for buying it in the U.S. including doctors visits, and it would have cost me over $300. In Mexico it cost me $3 over the counter.

If out have a friend (expatriate) living in Mexico you might have them buy you some, although it's probably all sold out by now.


.
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Apparently they have a different drug in mind to become the standard treatment?

:lmmoney:
 Quoting: CK Dexter Haven


thiss

Or the vaccine.

The drugs used in this treatment are all off-patent and manufactured by many companies. The total cost for the 5-day treatment regimen is $20.
LoneStarRising
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Another thing....this virus appears to live in you forever, like chicken pox or cold sores. Dont stop being vigilant in protecting yourself and staying healthy.
 Quoting: Prayandprepare000


Link?
Doc SavageModerator  (OP)
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03/29/2020 05:11 PM

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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Yay!

It can have serious side effects so be forewarned. Not as serious as dying of virus though.
 Quoting: Prayandprepare000


Actually, side effects are minimal compared to the formerly-used form (Chloroquine), and any side effects are usually seen only during long-term treatment, not short-term like with COVID-19.
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Rudy had a great Podcast yesterday with one of the first doctors to use this treatment here in the US:


LoneStarRising
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
NYC is using this and it isn't working as well as people think.

Keep in mind that the number to treat is astronomically high in a compensated health system.

For example, normal death rate is less than 1% in first world countries. So how many people do you have to treat before having statistically sound information that it helps?

You will need probably a sample size of at 3000 if it is amazing and upward to 10k to 20k if it's minor.

If you give 1000 people the drug, and no one dies, you averted 5 deaths. If you happen to have 4 deaths or 3 deaths, it is probably within statistical variance. If you averted all 5, you'd have to show this over a population of 2000 or 3000 with no deaths before having a p value less than 0.05, which would be stastically signnificant.

If you give this drug only to people who are already almost terminally ill, then you have to change the criteria on who is getting it and at what severity of disease.

This is an off label use for a medication that could be used for people who really need it for disabling autoimmune disease.

There's an opportunity cost to taking a drug that is in limited supply used for a drug that DOES work and then taking it to treat a ton of people where it "might work". Then all the people who normally would use it for their disease where it is KNOWN to work won't be able to get it and their morbidity goes up.

Catch 22.
 Quoting: Anonymous Coward 78516599


Apparently they have a different drug in mind to become the standard treatment?

:lmmoney:
 Quoting: CK Dexter Haven


Last Edited by CK Dexter Haven on 03/29/2020 05:22 PM
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
From the article:

The Democrats, the media, and people who despise the president don’t want these trials to succeed. Three Democrat governors have gone so far as to ban the use of the drug cocktail. And one has even threatened action against doctors who prescribe it. Which is an odd juxtaposition for the days we live in. It appears that the President cares more about their constituents in their states than their own governors do.

[link to townhall.com (secure)]
 Quoting: LoneStarRising


EXACTLY.

And the Dems are now terrified that trump's going to get mega-credit for promoting the treatment while Dems were downplaying it and hoping it would fail (more deaths means more potential blame for Trump).
Anonymous Coward
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Megastudy of Chloroquine (among other treatments) now underway:

[link to bgr.com (secure)]
Ryain

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03/29/2020 05:34 PM
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Yay!

It can have serious side effects so be forewarned. Not as serious as dying of virus though.
 Quoting: Prayandprepare000


Actually, side effects are minimal compared to the formerly-used form (Chloroquine), and any side effects are usually seen only during long-term treatment, not short-term like with COVID-19.
 Quoting: Doc Savage


I have a couple of auto-immune disorders and I'm on this medication. It's life changing for many people! Thanks for sticking up for us!

Was worried about my refill, but I had no problem getting it.
A lot of people on my other forum, are having a hard time getting it refilled.
Ryain
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
NYC is using this and it isn't working as well as people think.

Keep in mind that the number to treat is astronomically high in a compensated health system.

For example, normal death rate is less than 1% in first world countries. So how many people do you have to treat before having statistically sound information that it helps?

You will need probably a sample size of at 3000 if it is amazing and upward to 10k to 20k if it's minor.

If you give 1000 people the drug, and no one dies, you averted 5 deaths. If you happen to have 4 deaths or 3 deaths, it is probably within statistical variance. If you averted all 5, you'd have to show this over a population of 2000 or 3000 with no deaths before having a p value less than 0.05, which would be stastically signnificant.

If you give this drug only to people who are already almost terminally ill, then you have to change the criteria on who is getting it and at what severity of disease.

This is an off label use for a medication that could be used for people who really need it for disabling autoimmune disease.

There's an opportunity cost to taking a drug that is in limited supply used for a drug that DOES work and then taking it to treat a ton of people where it "might work". Then all the people who normally would use it for their disease where it is KNOWN to work won't be able to get it and their morbidity goes up.

Catch 22.
 Quoting: Anonymous Coward 78516599


there is no catch 22... RA is highly manageable via eating the right diet. i have a family member that went the "drugs" route at first and it made little difference... she changed her diet and voila!!! walking up and down stairs like a champ and walking 4 or 5 miles a day.

no one cares about a study right now for its prophylactic use (we can look at this after the crisis is abated) but people on their death beds gasping for air? it is a game changer. but the real kicker here is NIH already admitted it was effective back in 2005... yep... you heard right... munchkin boy fauci has known it worked since 2005.

[link to www.ncbi.nlm.nih.gov (secure)]

they are trying to usher in communism with this thing. as far as the deaths in the usa? i've been watching the numbers like a hawk... they were trending lower and lower and then all of a sudden? they reversed trend? yeah right. they changed reporting criteria.

.
CK Dexter Haven

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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
It is suspicious they're trying to discredit this treatment out of hand when there seems to be substantial evidence it may be very helpful.

Twitter going as far as to censor posts on it.
 Quoting: CK Dexter Haven


I promise you you will be wrong.


This is the dumbest shit I've ever seen pushed because of political reasons in all my years of living.


New Orleans doctors already shat all over this bogus shit two days ago. Said it was dangerous because of prolonged QT and liver problems.

I guarantee you this is nothing more than a political kick the can stunt by a bunch if neurotic devils.
 Quoting: Anonymous Coward 78469971


Wrong about what?
What did I say that's wrong?

This subject really pushes a nerve.
CK Dexter Haven

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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
I'm sure the Gates foundation will have the approved medicine available soon.

vaccinebill
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
NYC is using this and it isn't working as well as people think.
 Quoting: Anonymous Coward 78516599

You're referring to hospital usage--the governor has specifically forbidden outpatient prescription. The whole point here is that HCQ is best taken when symptoms first start, before the patient needs a hospital--or even before (as a preventative).

The Polish government approved chloroquine as a treatment for COVID-19 on March 12.

[link to twitter.com (secure)]

Poland, a nation of 38 million people, has suffered only 22 COVID-19 deaths.

[link to www.worldometers.info (secure)]

Last Edited by BeSkeptical on 03/29/2020 05:44 PM
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
No, I'm talking about ICU use. I have a few colleagues who are ICU doctors in NYC metropolitan area.
 Quoting: Anonymous Coward 78516599

Exactly. ICU is way too late! Frankly, you have just told us why NYC is swimming in COVID-19 deaths.

Tell them to prescribe HCQ on an outpatient basis, when symptoms first appear. (Cuomo be damned!)

And tell them to prescribe it for themselves as a preventative.

Last Edited by BeSkeptical on 03/29/2020 05:48 PM
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
No, I'm talking about ICU use. I have a few colleagues who are ICU doctors in NYC metropolitan area.
 Quoting: Anonymous Coward 78516599

Exactly. ICU is way too late! Tell them to prescribe HCQ on an outpatient basis, when symptoms first appear. And tell them to prescribe it for themselves as a preventative.
 Quoting: BeSkeptical


thiss

Almost all that need ICU have already developed Acute respiratory distress syndrome (ARDS.) Whole other set of issues once people reach that stage.
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Where can I buy some for prophylactic use?
 Quoting: Pilgrim001


My doctor refused.

Even for a close family member battling stage 4 cancer, and my asthmatic child.

California...
 Quoting: Anonymous Coward 65126451


Yay!

It can have serious side effects so be forewarned. Not as serious as dying of virus though.
 Quoting: Prayandprepare000


Actually, side effects are minimal compared to the formerly-used form (Chloroquine), and any side effects are usually seen only during long-term treatment, not short-term like with COVID-19.
 Quoting: Doc Savage


Your right that you do not want to take that drug for a long time. look up right here about side effects of quinines.
www.quinism.org
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
NYC is using this and it isn't working as well as people think.

Keep in mind that the number to treat is astronomically high in a compensated health system.

For example, normal death rate is less than 1% in first world countries. So how many people do you have to treat before having statistically sound information that it helps?

You will need probably a sample size of at 3000 if it is amazing and upward to 10k to 20k if it's minor.

If you give 1000 people the drug, and no one dies, you averted 5 deaths. If you happen to have 4 deaths or 3 deaths, it is probably within statistical variance. If you averted all 5, you'd have to show this over a population of 2000 or 3000 with no deaths before having a p value less than 0.05, which would be stastically signnificant.

If you give this drug only to people who are already almost terminally ill, then you have to change the criteria on who is getting it and at what severity of disease.

This is an off label use for a medication that could be used for people who really need it for disabling autoimmune disease.

There's an opportunity cost to taking a drug that is in limited supply used for a drug that DOES work and then taking it to treat a ton of people where it "might work". Then all the people who normally would use it for their disease where it is KNOWN to work won't be able to get it and their morbidity goes up.

Catch 22.
 Quoting: Anonymous Coward 78516599


there is no catch 22... RA is highly manageable via eating the right diet. i have a family member that went the "drugs" route at first and it made little difference... she changed her diet and voila!!! walking up and down stairs like a champ and walking 4 or 5 miles a day.

no one cares about a study right now for its prophylactic use (we can look at this after the crisis is abated) but people on their death beds gasping for air? it is a game changer. but the real kicker here is NIH already admitted it was effective back in 2005... yep... you heard right... munchkin boy fauci has known it worked since 2005.

[link to www.ncbi.nlm.nih.gov (secure)]

they are trying to usher in communism with this thing. as far as the deaths in the usa? i've been watching the numbers like a hawk... they were trending lower and lower and then all of a sudden? they reversed trend? yeah right. they changed reporting criteria.

.
 Quoting: Anonymous Coward 78535400


RA is very complex. The entity is not a one solution box. In fact, RA has subtypes and what is working for your family member doesn't necessarily work for all.

There are plenty of people who don't get better on this medication and are on biolgics like enbrel, humira, and remicade.

For those that are on it - getting great results - then having it pulled from them - that's devasating.
 Quoting: Anonymous Coward 78516599


i find it almost a zero probability that anyone has had this med "pulled" from them. that said? RA isn't a contagious virus that has shut down a country and is killing people in the thousands with the potential for a lot more. let's get our priorities straight!

.
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Thanks for this info. Pray to God they clear it for everyone asap. Thousands and thousands of lives could be saved.
Anonymous Coward
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Re: TOWNHALL (MARCH 29) -- Hydroxychloroquine: Help Is On The Way!
Word is getting around. Even NBC News said last night that hydroxychloroquine might just work. They want to be on the right side of history.





GLP