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Jan 24, 2013 (CIDRAP News) – In a new analysis of serologic studies from 19 countries, researchers estimate that about 24% of the population were infected with the 2009 H1N1 influenza (pH1N1) virus during the first year of the pandemic, a finding modestly higher than what US health officials estimated in the immediate aftermath of the pandemic.
When the estimate is combined with recent estimates of the pandemic's death toll, it appears that about 1 in 5,000 (0.02%) of those infected with the virus died, says the report by a large team of researchers from the World Health Organization (WHO) and many other
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Estimating age‐specific cumulative incidence for the 2009 influenza pandemic: a meta‐analysis of A(H1N1)pdm09 serological studies from 19 countries
Maria D. Van Kerkhove Siddhivinayak Hirve Artemis Koukounari Anthony W. Mounts for the H1N1pdm serology working group
First published:21 January 2013
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Citations: 103
Results
Data from 27 published/unpublished studies from 19 countries/administrative regions – Australia, Canada, China, Finland, France, Germany, Hong Kong SAR, India, Iran, Italy, Japan, Netherlands, New Zealand, Norway, Reunion Island, Singapore, United Kingdom, United States, and Vietnam – were eligible for inclusion. The overall age-standardized pre-pandemic prevalence of cross-reactive antibodies was 5% (95%CI 3–7%) and varied significantly by age with the highest rates among persons >65 years old (14% 95%CI 8–24%). Overall age-standardized H1N1pdm cumulative incidence was 24% (95%CI 20–27%) and varied significantly by age with the highest in children 5–19 (47% 95%CI 39–55%) and 0–4 years old (36% 95%CI 30–43%).
Conclusions
Our results offer unique insight into the global impact of the H1N1 pandemic and highlight the need for standardization of seroepidemiological studies and for their inclusion in pre-pandemic preparedness plans. Our results taken together with recent global pandemic respiratory-associated mortality estimates suggest that the case fatality ratio of the pandemic virus was approximately 0.02%.
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When you're comparing CoVid to the Flu, ya'll are off by a factor of 10.
Last Edited by RikardAron on 04/24/2020 10:32 PM