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COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)

 
ParamedicUK

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02/24/2021 03:54 PM

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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Thought provoking paper. Only one study, but inch by inch perhaps accurate understanding will come about. Uncle Doom way back in the day on the other thread was one of the first to mention prions linked to this virus, I do believe. Now perhaps the C19 vaccines also have such a link, and that's a very bad thing, if so.

[link to scivisionpub.com (secure)]

Selections from the paper's Abstract

Development of new vaccine technology has been plagued with problems in the past. The current RNA based SARS-CoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing. In this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine recipients. The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma (FUS) into their pathologic prion conformations. The results indicate that the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations. ...
The folding of TDP-43 and FUS into their pathologic prion confirmations is known to cause ALS, front temporal lobar degeneration, Alzheimer’s disease and other neurological degenerative diseases. ...

The enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit.
 Quoting: Dosha


Wtf - this is in the discussion ....

Discussion
There is an old saying in medicine that “the cure may be worse than the disease.” The phrase can be applied to vaccines. In the current paper the concern is raised that the RNA based COVID vaccines have the potential to cause more disease than the epidemic of COVID-19. This paper focuses on a novel potential adverse event mechanism causing prion disease which could be even more common and debilitating than the viral infection the vaccine is designed to prevent. While this paper focuses on one potential adverse event there are multiple other potential fatal adverse events as discussed below.
ParamedicUK

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02/24/2021 03:56 PM

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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
... sorry

UK Keep Calm Sma

Last Edited by ParamedicUK on 02/24/2021 03:57 PM
lightning1977

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02/24/2021 04:08 PM
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
... sorry

UK Keep Calm Sma
 Quoting: ParamedicUK


Are you ok today para? You seem off colour.
ParamedicUK

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02/24/2021 04:12 PM

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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
... sorry

UK Keep Calm Sma
 Quoting: ParamedicUK


Are you ok today para? You seem off colour.
 Quoting: lightning1977


Shit day at work but they made it to ED just.
ParamedicUK

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02/24/2021 04:12 PM

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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
..

Last Edited by ParamedicUK on 02/24/2021 04:12 PM
Serenity Now

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02/24/2021 04:37 PM

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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)


Wow read the whole thread - numbers rising madly in a lot of mainland countries !!!
 Quoting: ParamedicUK


It is so nice to be here and not have to listen to George claim otherwise when the numbers don't lie...but debating him was akin to banging your head on a brick wall...
 Quoting: P-E Georgia Geoprepper



I have to be honest and say that he helped me yesterday. I am repeating the story here in case anyone missed it or the information on the other thread.

My husband is a naval officer stationed in Italy, and he will have to have a vaccine for an upcoming mission in May. It is not the US government or the Italian government requiring it, by the way. I want to make that clear. Another country's ship is involved, so it's their mandate.

In George's many posts yesterday, he mentioned that if you don't want to take the mRNA vaccine, then wait for the Johnson & Johnson one, which apparently is not mRNA and is also one dose. He said it would be emergency approved this week.

I didn't know the J&J vaccine was not mRNA. I asked George a couple of questions, and he was nice to me and provided some answers.

Today the news indicates that the J&J vaccine will be emergency approved by the end of the week.

We were able to make some phone calls to the hospital on base today to ask them if they are going to get the J&J vaccine. They don't know, but I'm hopeful they will get it. If my husband has to get a vaccine, I want it to be the J&J (non-mRNA) one.

Sorry for the wall of text. I hope this may help someone else who might not be on the other thread. :)
First tell the truth, then give your opinion....
Serenity Now

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02/24/2021 04:47 PM

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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
..
 Quoting: ParamedicUK



Hang in there, hinky. ;)
First tell the truth, then give your opinion....
ParamedicUK

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02/24/2021 04:49 PM

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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
 Quoting: CoronaCoaster


Wow read the whole thread - numbers rising madly in a lot of mainland countries !!!
 Quoting: ParamedicUK


It is so nice to be here and not have to listen to George claim otherwise when the numbers don't lie...but debating him was akin to banging your head on a brick wall...
 Quoting: P-E Georgia Geoprepper



I have to be honest and say that he helped me yesterday. I am repeating the story here in case anyone missed it or the information on the other thread.

My husband is a naval officer stationed in Italy, and he will have to have a vaccine for an upcoming mission in May. It is not the US government or the Italian government requiring it, by the way. I want to make that clear. Another country's ship is involved, so it's their mandate.

In George's many posts yesterday, he mentioned that if you don't want to take the mRNA vaccine, then wait for the Johnson & Johnson one, which apparently is not mRNA and is also one dose. He said it would be emergency approved this week.

I didn't know the J&J vaccine was not mRNA. I asked George a couple of questions, and he was nice to me and provided some answers.

Today the news indicates that the J&J vaccine will be emergency approved by the end of the week.

We were able to make some phone calls to the hospital on base today to ask them if they are going to get the J&J vaccine. They don't know, but I'm hopeful they will get it. If my husband has to get a vaccine, I want it to be the J&J (non-mRNA) one.

Sorry for the wall of text. I hope this may help someone else who might not be on the other thread. :)
 Quoting: Serenity Now


Is it better / hmmm DNA based / think not:

[link to www.nytimes.com (secure)]

The Johnson & Johnson vaccine is based on the virus’s genetic instructions for building the spike protein. But unlike the Pfizer-BioNTech and Moderna vaccines, which store the instructions in single-stranded RNA, the Johnson & Johnson vaccine uses double-stranded DNA.

DNA Inside an Adenovirus

The researchers added the gene for the coronavirus spike protein to another virus called Adenovirus 26. Adenoviruses are common viruses that typically cause colds or flu-like symptoms. The Johnson & Johnson team used a modified adenovirus that can enter cells but can’t replicate inside them or cause illness.

Johnson & Johnson’s vaccine comes out of decades of research on adenovirus-based vaccines. In July, the first one was approved for general use — a vaccine for Ebola, also made by Johnson & Johnson. The company is also running trials on adenovirus-based vaccines for other diseases, including H.I.V. and Zika. Some other coronavirus vaccines are also based on adenoviruses, such as the one developed by the University of Oxford and AstraZeneca using a chimpanzee adenovirus.

Adenovirus-based vaccines for Covid-19 are more rugged than mRNA vaccines from Pfizer and Moderna. DNA is not as fragile as RNA, and the adenovirus’s tough protein coat helps protect the genetic material inside. As a result, the Johnson & Johnson vaccine can be refrigerated for up to three months at 36–46°F (2–8°C).

Bugger that!!!! The thought of DNA concerns me?

UK Keep Calm

Last Edited by ParamedicUK on 02/24/2021 04:54 PM
Anonymous Coward
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Cross-posted from main big thread:

Remember in about September, the ridiculous drive to get everyone vaccinated against flu??

I was saying to my family, and probably also on this thread, that I didn't believe there would BE a flu season this winter.
I was right.

Important because there are several papers showing that those vaccinated against flu have a higher propensity for Coronavirus infection than those who are unvaccinated. Odd that it works out like that, but that's the science.
(skeptics, please look back in this thread to around 23-30 Sept 2020 for the papers..)


[link to www.independent.co.uk (secure)]
(23 Feb 2021)
Not a single case of flu detected by Public Health England this year ...

1 day ago ... Not a single case of influenza has been detected by public health officials in England for the past seven weeks, with infection rates at historic lows...
Serenity Now

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02/24/2021 05:18 PM

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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
It's still DNA based? [Expletive deleted.] Thank you, PK, hang in there, friend.
First tell the truth, then give your opinion....
Anonymous Coward
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02/24/2021 05:59 PM
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Another cross-post from the Big Thread:


[link to thehill.com (secure)]
(<50%)

Vaccine developers will not have to conduct lengthy clinical trials to evaluate the effectiveness of shots tailored to fight new coronavirus variants, according to new guidance from the Food and Drug Administration (FDA).

According to the guidance released Monday, developers will not need large randomized control trials comparing it to a placebo.

Instead, the FDA said it recommended companies submit data from small trials comparing a person's immune response to a vaccine that has already been authorized.



BUT FOR IVERMECTIN...
we can't possibly use it because there aren't enough double-blind randomised control trials... despite it being used for 40 yrs in the wild already... and having basically zero adverse effects compared to vaccines....
lightning1977

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02/24/2021 06:00 PM
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Large outbreak at Strangeways Prison.



Schools back in a week and a half. Almost a completely unvaccinated cohort. Roughly 3,000,000 children and 700,000 staff. What could go wrong.

The levels of virus are surely still far too high.
lightning1977

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02/24/2021 06:03 PM
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
SA variant pops up in London.

lightning1977

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02/24/2021 06:07 PM
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Some Welsh schools shut after one day on reopening due to large outbreak at Gwynedd Hospital.

Anonymous Coward
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
...


Wow read the whole thread - numbers rising madly in a lot of mainland countries !!!
 Quoting: ParamedicUK


It is so nice to be here and not have to listen to George claim otherwise when the numbers don't lie...but debating him was akin to banging your head on a brick wall...
 Quoting: P-E Georgia Geoprepper



I have to be honest and say that he helped me yesterday. I am repeating the story here in case anyone missed it or the information on the other thread.

My husband is a naval officer stationed in Italy, and he will have to have a vaccine for an upcoming mission in May. It is not the US government or the Italian government requiring it, by the way. I want to make that clear. Another country's ship is involved, so it's their mandate.

In George's many posts yesterday, he mentioned that if you don't want to take the mRNA vaccine, then wait for the Johnson & Johnson one, which apparently is not mRNA and is also one dose. He said it would be emergency approved this week.

I didn't know the J&J vaccine was not mRNA. I asked George a couple of questions, and he was nice to me and provided some answers.

Today the news indicates that the J&J vaccine will be emergency approved by the end of the week.

We were able to make some phone calls to the hospital on base today to ask them if they are going to get the J&J vaccine. They don't know, but I'm hopeful they will get it. If my husband has to get a vaccine, I want it to be the J&J (non-mRNA) one.

Sorry for the wall of text. I hope this may help someone else who might not be on the other thread. :)
 Quoting: Serenity Now


Is it better / hmmm DNA based / think not:

[link to www.nytimes.com (secure)]

The Johnson & Johnson vaccine is based on the virus’s genetic instructions for building the spike protein. But unlike the Pfizer-BioNTech and Moderna vaccines, which store the instructions in single-stranded RNA, the Johnson & Johnson vaccine uses double-stranded DNA.

DNA Inside an Adenovirus

The researchers added the gene for the coronavirus spike protein to another virus called Adenovirus 26. Adenoviruses are common viruses that typically cause colds or flu-like symptoms. The Johnson & Johnson team used a modified adenovirus that can enter cells but can’t replicate inside them or cause illness.

Johnson & Johnson’s vaccine comes out of decades of research on adenovirus-based vaccines. In July, the first one was approved for general use — a vaccine for Ebola, also made by Johnson & Johnson. The company is also running trials on adenovirus-based vaccines for other diseases, including H.I.V. and Zika. Some other coronavirus vaccines are also based on adenoviruses, such as the one developed by the University of Oxford and AstraZeneca using a chimpanzee adenovirus.

Adenovirus-based vaccines for Covid-19 are more rugged than mRNA vaccines from Pfizer and Moderna. DNA is not as fragile as RNA, and the adenovirus’s tough protein coat helps protect the genetic material inside. As a result, the Johnson & Johnson vaccine can be refrigerated for up to three months at 36–46°F (2–8°C).

Bugger that!!!! The thought of DNA concerns me?

:UK Keep Calm:
 Quoting: ParamedicUK


The Adenovirus vector can be an issue - because the body recognises it after it has seen it before.. so it will be unclear whether someone who had the AstraZeneca vaccine will be able to take the J&J vaccine...because their immune system will destroy the J&J adenovirus before it can work.

In addition sub-Saharan Africa will have a problem:

Quoting Professor Clancy:
The adenovirus vector cannot be relied on for second immunisations (as antibody to the simian virus carrier limits response). For the same reason, the vector vaccine has limited value in Sub Saharan Africa, where exposure to simian viruses is common.
[link to quadrant.org.au (secure)]
lightning1977

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02/24/2021 06:14 PM
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Nissan production lines grind to a halt over parts shortages blamed on the pandemic

lightning1977

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02/24/2021 06:22 PM
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Spain like the UK seemingly bricking it over the variants it seems.

lightning1977

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02/24/2021 06:25 PM
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Deaths drop 20% in last week.



Hopefully not the calm before the mainland European storm!
CoronaCoaster  (OP)
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02/24/2021 06:29 PM

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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
A friend forwarded this to me yesterday, from Yahoo News (oxymoron for sure) cool2

[link to news.yahoo.com (secure)]

My gist from the article:

This mutation emerged in May, so been here awhile, has become dominant strain in CA. Easier spreading, more evasive to antibodies from prior infection or vaccine.



Some of the article:

B.1.427/B.1.429's genome includes three mutations that affect the crucial spike protein, which the virus uses to sneak into human cells and convert them into factories for its own production. One of those three mutations, dubbed L452R, affects the so-called receptor binding domain, helping the virus attach more firmly to target cells.

That adaptation has not been seen in coronavirus variants that have caused worry elsewhere.

In a UCSF lab, scientists found that the L452R mutation alone made the California strain more damaging as well. A coronavirus engineered to have only that mutation was able to infect human lung tissue at least 40% more readily than were circulating variants that lacked the mutation. Compared with those so-called wild-type strains, the engineered virus was more than three times more infectious. ...
 Quoting: Dosha


Took them quite a while to get a better idea about that California variant.

We could be in the early stages of a whole new problematic variant spreading right now and we might not know the details about its mutation until summer.

Last Edited by CoronaCoaster on 02/24/2021 06:30 PM
CoronaCoaster  (OP)
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
You guys are doing an awesome job with the news on this thread. I don't have much time for anything other than reading when I have a few minutes spare so appreciate the work you're all doing to contribute.

Stay safe!
 Quoting: BertTabernacle


cheers
Anonymous Coward
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02/24/2021 06:43 PM
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
I have a strange feeling that the UK is sleep walking into a potential summer of chaos. The media outlets are all focusing on the feel good headlines of a Mask free summer and music festivals. Once this seeps into the psyche of the general public people’s guards are going to start dropping.

I hope I’m being overly cautious but it feels very premature to celebrate right now. Until schools reopen we won’t know for sure what the situation is.
CoronaCoaster  (OP)
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02/24/2021 06:46 PM

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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Cross-posted from main big thread:

Remember in about September, the ridiculous drive to get everyone vaccinated against flu??

I was saying to my family, and probably also on this thread, that I didn't believe there would BE a flu season this winter.
I was right.

Important because there are several papers showing that those vaccinated against flu have a higher propensity for Coronavirus infection than those who are unvaccinated. Odd that it works out like that, but that's the science.
(skeptics, please look back in this thread to around 23-30 Sept 2020 for the papers..)


[link to www.independent.co.uk (secure)]
(23 Feb 2021)
Not a single case of flu detected by Public Health England this year ...

1 day ago ... Not a single case of influenza has been detected by public health officials in England for the past seven weeks, with infection rates at historic lows...
 Quoting: Anonymous Coward 78062583


One of the suggestions given by Dr. Paul Cottrell (one of his videos was posted here recently) was sars-cov2 is a stronger virus than the flu, and as a result after you've been infected with sars-cov2 in the short-term you are less susceptible to infection from the flu. He managed to explain it more eloquently than I can, but that was the gist of what he said.

Aside from that, the one thing to keep in mind is the R rate of flu in normal times is about 1.4. Therefore all these covid restrictions and mitigations would have likely knocked the R rate way below zero and made it very hard for flu to spread.

Last Edited by CoronaCoaster on 02/24/2021 07:43 PM
CoronaCoaster  (OP)
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Spain like the UK seemingly bricking it over the variants it seems.


 Quoting: lightning1977


Probably traumatised after the outbreak last Spring. Madrid got absolutely wrecked, and the people there believe the Gov concealed the true covid death toll.
CoronaCoaster  (OP)
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
I have a strange feeling that the UK is sleep walking into a potential summer of chaos. The media outlets are all focusing on the feel good headlines of a Mask free summer and music festivals. Once this seeps into the psyche of the general public people’s guards are going to start dropping.

I hope I’m being overly cautious but it feels very premature to celebrate right now. Until schools reopen we won’t know for sure what the situation is.
 Quoting: Anonymous Coward 79088381


Going to be a shitshow IMO. Even if the vaccine is effective, the rollout will still take a while longer and the plan to lift the Covid restrictions is too fast.

They thought wishful thinking was going to work last year and it didn't. Nothing has been learned as they are pushing the wishful thinking again.
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CoronaCoaster  (OP)
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CoronaCoaster  (OP)
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Anonymous Coward
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02/24/2021 07:18 PM
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Very good and informative thread, thanks!
CoronaCoaster  (OP)
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02/24/2021 07:21 PM

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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Covid hospital admissions are falling, so the strain on hospitals is going down? Maybe not because now admissions for COPD and asthma patients are increasing

CoronaCoaster  (OP)
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Re: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// J&J vaccine linked to serious blood clots ! (pg. 142)
Very good and informative thread, thanks!
 Quoting: Anonymous Coward 79569067


Thanks. And my thanks aswell to y'all who contribute in this thread.

Also here's another thread that was created recently which has some decent info.


Thread: It’s not about the death rate ... HIV doesn’t kill folks for years.... rethink how sars cov 2 works.... it's not going to be pretty





GLP