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Message Subject COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// October Lockdown for UK (pg. 774)
Poster Handle Anonymous Coward
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Wow read the whole thread - numbers rising madly in a lot of mainland countries !!!
 Quoting: ParamedicUK


It is so nice to be here and not have to listen to George claim otherwise when the numbers don't lie...but debating him was akin to banging your head on a brick wall...
 Quoting: P-E Georgia Geoprepper



I have to be honest and say that he helped me yesterday. I am repeating the story here in case anyone missed it or the information on the other thread.

My husband is a naval officer stationed in Italy, and he will have to have a vaccine for an upcoming mission in May. It is not the US government or the Italian government requiring it, by the way. I want to make that clear. Another country's ship is involved, so it's their mandate.

In George's many posts yesterday, he mentioned that if you don't want to take the mRNA vaccine, then wait for the Johnson & Johnson one, which apparently is not mRNA and is also one dose. He said it would be emergency approved this week.

I didn't know the J&J vaccine was not mRNA. I asked George a couple of questions, and he was nice to me and provided some answers.

Today the news indicates that the J&J vaccine will be emergency approved by the end of the week.

We were able to make some phone calls to the hospital on base today to ask them if they are going to get the J&J vaccine. They don't know, but I'm hopeful they will get it. If my husband has to get a vaccine, I want it to be the J&J (non-mRNA) one.

Sorry for the wall of text. I hope this may help someone else who might not be on the other thread. :)
 Quoting: Serenity Now


Is it better / hmmm DNA based / think not:

[link to www.nytimes.com (secure)]

The Johnson & Johnson vaccine is based on the virus’s genetic instructions for building the spike protein. But unlike the Pfizer-BioNTech and Moderna vaccines, which store the instructions in single-stranded RNA, the Johnson & Johnson vaccine uses double-stranded DNA.

DNA Inside an Adenovirus

The researchers added the gene for the coronavirus spike protein to another virus called Adenovirus 26. Adenoviruses are common viruses that typically cause colds or flu-like symptoms. The Johnson & Johnson team used a modified adenovirus that can enter cells but can’t replicate inside them or cause illness.

Johnson & Johnson’s vaccine comes out of decades of research on adenovirus-based vaccines. In July, the first one was approved for general use — a vaccine for Ebola, also made by Johnson & Johnson. The company is also running trials on adenovirus-based vaccines for other diseases, including H.I.V. and Zika. Some other coronavirus vaccines are also based on adenoviruses, such as the one developed by the University of Oxford and AstraZeneca using a chimpanzee adenovirus.

Adenovirus-based vaccines for Covid-19 are more rugged than mRNA vaccines from Pfizer and Moderna. DNA is not as fragile as RNA, and the adenovirus’s tough protein coat helps protect the genetic material inside. As a result, the Johnson & Johnson vaccine can be refrigerated for up to three months at 36–46°F (2–8°C).

Bugger that!!!! The thought of DNA concerns me?

:UK Keep Calm:
 Quoting: ParamedicUK


The Adenovirus vector can be an issue - because the body recognises it after it has seen it before.. so it will be unclear whether someone who had the AstraZeneca vaccine will be able to take the J&J vaccine...because their immune system will destroy the J&J adenovirus before it can work.

In addition sub-Saharan Africa will have a problem:

Quoting Professor Clancy:
The adenovirus vector cannot be relied on for second immunisations (as antibody to the simian virus carrier limits response). For the same reason, the vector vaccine has limited value in Sub Saharan Africa, where exposure to simian viruses is common.
[link to quadrant.org.au (secure)]
 
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