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Message Subject COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// October Lockdown for UK (pg. 774)
Poster Handle Dutchy20
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The novel coronavirus’ spike protein plays additional key role in illness. Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease.

LA JOLLA—Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells. Now, a major new study shows that they also play a key role in the disease itself.

The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system on a cellular level. The findings help explain COVID-19’s wide variety of seemingly unconnected complications, and could open the door for new research into more effective therapies.

“A lot of people think of it as a respiratory disease, but it’s really a vascular disease,” says Assistant Research Professor Uri Manor, who is co-senior author of the study. “That could explain why some people have strokes, and why some people have issues in other parts of the body. The commonality between them is that they all have vascular underpinnings.”

[link to www.salk.edu (secure)]
 Quoting: ShylaRose

"attacks the vascular system on a cellular level." Holy crap, that's every organ in the body. You really must do everything you can to not catch this monster!
hiding
 Quoting: Lago


I feel like a canary in the coal mine. Just over four months since my Covid positive test. Fuck.
 Quoting: lightning1977

This may be what all this "long covid" is about. The virus is circulating in the vascular, or blood circulatory, system until it finds a vulnerable organ/organs?
 Quoting: Lago


Proper answer is "I don't know", but in a attempt not to be boring, I'll go with "I don't think so". My understanding of the underlying process is shaky at best but it seems to me the actual "infection" stage, where the virus does damage is mostly limited to two-three weeks. There are extreme's where it's much longer and for most it's shorter but for a ball park figure that seems about right.

The problem is given that the virus can effect (damage) blood vessels, it can effect every part of the body. I'm still iffy on the viability of replication outside some of the sweet spots like the lungs etc. Even though the window for actual damage from the virus would then be short the cascading effects can linger and present with delay.

That might be all wrong though, if it even makes sense.
 
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