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REPORT COPYRIGHT VIOLATION IN REPLY
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Message Subject
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COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects /// October Lockdown for UK (pg. 774)
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Poster Handle
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Anonymous Coward |
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Post Content
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One of the interesting possibilities they bring up(altho considered less likely by them for now) is 'antigenic sin' which sounds rather like ADE? quote Antigenic sin (vaccination resulting in an immune response that is dominated by antibodies to previously experienced viruses/vaccines) meaning that it becomes difficult to revaccinate to induce antibodies to the new strains.:verydamned: New one on me.... antigenic sin leads to ADE, if I read correctly... Antibody Dependent Enhancement Due to Original Antigenic Sin and the Development of SARS
Less than 50% In conclusion, the development of IgG against SARS-CoV-2 in the course of COVID-19 might not be a simple sign of viral clearance and developing protection against the virus. On the contrary, due to cross-reaction to related coronavirus strains from earlier infections, the patient's viral history of coronavirus infection might be crucial to the severity of the course of the current infection with SARS-CoV-2, a phenomenon that has been called in the context of influence infections “original antigenic sin.” Furthermore, it poses a note of caution when treating COVID-19 patients with convalescent sera. [ link to www.ncbi.nlm.nih.gov (secure)]
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