Thread: Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus
Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus
01/10/2021 08:21 AM

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WARNING - WARNING - WARNING

Thread: Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus
Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the

SARS Virus
01/10/2021 08:21 AM

[link to journals.plos.org (secure)]

Immunization with SARS Coronavirus Vaccines Leads to
Pulmonary Immunopathology on Challenge with the SARS
Virus
Chien-Te Tseng,Elena Sbrana,Naoko Iwata-Yoshikawa,Patrick C. Newman,Tania Garron,Robert L. Atmar,Clarence J. Peters,Robert B. Couch

Results
All vaccines induced serum neutralizing antibody with
increasing dosages and/or alum significantly increasing
responses. Significant reductions of SARS-CoV two
days after challenge was seen for all vaccines and prior
live SARS-CoV. All mice exhibited histopathologic
changes in lungs two days after challenge
including all animals vaccinated (Balb/C and C57BL/6) or
given live virus, influenza vaccine, or PBS
suggesting infection occurred in all.

Histopathology seen in animals given one of the SARS-CoV
vaccines was uniformly a Th2-type immunopathology with
prominent eosinophil infiltration, confirmed
with special eosinophil stains. The pathologic changes
seen in all control groups lacked the eosinophil
prominence.

Conclusions
These SARS-CoV vaccines all induced antibody and
protection against infection with SARS-CoV. However,
challenge of mice given any of the vaccines led to
occurrence of Th2-type immunopathology suggesting
hypersensitivity to SARS-CoV
components was induced. Caution in proceeding to
application of a SARS-CoV vaccine in humans is indicated.

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notice the FLU Vaccine may cause this reaction.

histopathologic changes in lungs two days after challenge
including all animals vaccinated (Balb/C and C57BL/6) or
given live virus, influenza vaccine, or PBS
suggesting infection occurred in all.

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To put it short at bluntly:
CoVid Vac Leads to Lung Disease on Challenge with the
SARS Virus and the Flu Vaccine increases this Reaction.