"..... unfortunately there's no way to change their minds with logic or reason. It's a spiritual stronghold they're under (a "spell", brianwashing, etc.).
You can't break a spell with logic or reason; you need divine intervention that can only come when the affected person wants it FROM THE HEART.
This normally only comes after intense suffering."

I think you are right.
A STRONGHOLD.
A spell cast by all the media programming.

It's interesting that you mentioned suffering. Intense suffering is what makes people cry out to God and ask for help. To be humbled and broken.

But, after taking this shot, will their dna be changed? Like into a hybrid human?
God doesn't allow hybrids into heaven.

The above argument doesn't even faze these people.

I'm dealing with the exact same thing. There are 2 that I know - they cannot HEAR what I am telling them.
They get angry and insist they want to take it.

I've never seen anything like this in my life.