So the question earlier about cases dropping....

Yes, testing probably needs to be reset....

Could mutations of SARS-CoV-2 suppress diagnostic detection?

Less than 50%

With this in mind, and as new variants of SARS-CoV-2 are identified, it is critical that diagnostic tests for the virus in wide use are regularly reconfigured. In particular, diagnostic tests configured to use a single monoclonal antibody, especially those targeting S protein, must revalidate the performance of the test against emerging strains of SARS-CoV-2 or consider adapting the assay to the detection of N protein using high-affinity polyclonal antibodies as critical detection reagents.

[link to www.nature.com (secure)]

February 18, 2021