The Bible wasn't created in at the Council of Nicea - nor by Constantine.

It was in 382 at the Council of Rome, well past Constantine's time.

The Catholic Church didn't "publish" the original Bible.

The various "Bishops" from individual churches merely "chose" various books - at the Council of Rome in 382 - that were already the most popular in the various churches - then translated them into Latin - and printed them for use by CLERGY ONLY.

---AD 96 Clement Bishop of Rome quotes / refers to 11 books used for the New Testament including Matthew, Mark and Luke.

---AD 108 Ignatius Bishop of Antioch quotes / refers to 24 books used for the New Testament including all 4 Gospels.

---AD 110 Polycarp Bishop of Smyrna quotes / refers to 18 books used for the New Testament including all 4 Gospels.

About the only things that were "changed" were certain verses that support the "trinity", first mentioned by Theophilus of Antioch in the late 2nd century.

There's a reason why various old manuscripts of the various books of the New Testament, and even of the OT, have lasted 1900+ years.

Divine intervention.

Those manuscripts, at the least, have lasted through...

-the Roman wars in the Middle East of the 1st / 2nd Century
-the 200+ years of Roman persecution of Christians and Hebrews that began with Nero
-the "trinitarian" changes made to the Bible beginning around Tertullian's time
-the invasions / expansion of Islam that began after Muhammad's death in 632 AD

AD 96 Clement Bishop of Rome quotes / refers to 11 books used for the New Testament including Matthew, Mark and Luke.

AD 108 Ignatius Bishop of Antioch quotes / refers to 24 books used for the New Testament including all 4 Gospels.

AD 110 Polycarp Bishop of Smyrna quotes / refers to 18 books used for the New Testament including all 4 Gospels.