HUGE! Study finds COVID vaxes result in WEAKER, LESSER immune response to other viruses, stimuli | |
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Funney
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samanthasunflower
User ID: 78260147 United States 07/29/2021 02:31 PM Report Abusive Post Report Copyright Violation | Re: HUGE! Study finds COVID vaxes result in WEAKER, LESSER immune response to other viruses, stimuli Whether or not the vaccine actually does anything to prevent diseases is another story. But it does weekend the immune system for everything else out there. |
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Anonymous Coward User ID: 80281125 United States 07/29/2021 02:47 PM Report Abusive Post Report Copyright Violation | Re: HUGE! Study finds COVID vaxes result in WEAKER, LESSER immune response to other viruses, stimuli I hate to break it to you. But all vaccines do this. Ever notice how so many people complain about catching the flu after they get a flu shot. They most likely aren't catching the flu. They're simply catching whatever cold is going around. A cold that they probably would not have gotten if their immune system was not weakened by a vaccine Quoting: samanthasunflower Whether or not the vaccine actually does anything to prevent diseases is another story. |
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Anonymous Coward User ID: 80281125 United States 07/29/2021 03:11 PM Report Abusive Post Report Copyright Violation | Re: HUGE! Study finds COVID vaxes result in WEAKER, LESSER immune response to other viruses, stimuli Surprisingly, the production of the monocyte-derived cytokines TNF-α, IL-1β and IL-1Ra tended to be lower after stimulation of PBMCs from vaccinated individuals with either the standard SARS-CoV-2 strain or heterologous Toll-like receptor ligands (Figures 1 and 2). TNF-α production (Figure 1B-1G) following stimulation with the TLR7/8 agonist R848 of peripheral blood mononuclear cells from volunteers was significantly decreased after the second vaccination (Figure 1C). The same trend was observed after stimulation with the TLR3 agonist poly I:C (Figure 1D), although the difference did not reach statistical significance. In contrast, the responses to the fungal pathogen Candida albicans were higher after the first dose of the vaccine (Figure 1G). The impact of the vaccination on IL-1β production was more limited (Figure 2A-2F), though the response to C. albicans was significantly increased (Figure 2F). The production of the anti-inflammatory cytokine IL-1Ra (Figure 2G-2L) was reduced in response to bacterial lipopolysaccharide (LPS) and C. albicans after the second vaccination (Figure 2K, 2L), which is another argument for a shift towards stronger inflammatory responses to fungal stimuli after vaccination. IL-6 responses were similarly decreased, though less pronounced (data not shown). Quoting: The study inhibition of innate immune responses may diminish anti-viral responses. Type I interferons also play a central role in the pathogenesis and response against viral infections, including COVID-19 (Hadjadj et al., 2020). With this in mind, we also assessed the production of IFN-α by immune cells of the volunteers after vaccination. Although the concentrations of IFN-α were below the detection limit of the assay for most of the stimuli, we observed a significant reduction in the production if IFN-α secreted after stimulation with poly I:C and R848 after the administration of the second dose of the vaccine (Figure 1H, 1I). This may hamper the initial innate immune response against the virus, as defects in TLR7 have been shown to result in and increased susceptibility to COVID-19 in young males (Van Der Made et al., 2020). These results collectively demonstrate that the effects of the BNT162b2 vaccine go beyond the adaptive immune system and can also modulate innate immune responses. Quoting: The studyIntriguingly, the BNT162b2 vaccine induces reprogramming of innate immune responses as well, and this needs to be taken into account: in combination with strong adaptive immune responses, this could contribute to a more balanced inflammatory reaction during COVID-19 infection, or it may contribute to a diminished innate immune response towards the virus. Quoting: The study[link to www.medrxiv.org (secure)] |
Starburne
User ID: 80668951 South Africa 07/29/2021 03:23 PM Report Abusive Post Report Copyright Violation | Re: HUGE! Study finds COVID vaxes result in WEAKER, LESSER immune response to other viruses, stimuli Yeah, most here knew this last year already, it's common sense. Quoting: Anonymous Coward 72530568 The Big Pharma is creating life-long dependents with these vaxxes* You will die if you don't get your boosters and bi-annual follow-up shots!! Right. First the vax wipes your immune system. It is like it gives you HIV. Then for the rest of your life you are dependent on Big Pharma to stay alive. This study is big news. Especially amongst the younger generation, their immune systems were fine before the vax, but now the numbers of their infections and death rates are skyrocketing "I have no special talent, I am only passionately curious." -Albert Einstein |
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