Cellular protein that acts as a receptor for Ebola virus and Marburg virus.

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What is the receptor for Ebola?

Image result for TIM-1 protein binding

PtdSer receptors include Gas6 or protein S and TAM family receptors (TYRO3, AXL and MER).

It is suggested that EBOV enters cells through endocytosis clathrin [41].



In our opinion, the best way to reduce devastating action of EBOV is the collective inhibition of GP and VP30. The inhibition of GP is to reduce the side effects caused by the GP.


7. Conclusions


Based on the data presented in this chapter, Ebola has developed multiple pathways and modes for the evasion of the immune system and internalization in target cells. Further studies are necessary for a good understanding of the entry mechanism. However, the specific proteins of virus or even the cDNA genome disassociated of proteins can be studied in BSL-2 because the effects of virus depends on the presence of genome associated with structural and functional proteins, which allows to study the virus in laboratories at biosafety level 3 or 2. They may even accelerate the process of finding new inhibitors by pharmaceutical and vaccination companies.