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Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses

 
Constanttine
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09/23/2021 12:29 PM

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Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses
Vanderbilt University Medical Center says technology it developed has led to the discovery of an “ultra-potent” monoclonal antibody against COVID-19 and variants, including delta.



VUMC made the announcement Wednesday, saying the antibody can neutralize against SARS-CoV-2, the virus behind COVID-19. The research was published in “Cell Reports” earlier this month.



Researchers explain the technology behind the discovery is called LIBRA-seq, or Linking B-cell Receptor to Antigen Specificity through sequencing. It helped speed up the discovery.



“This is one way to proactively build a repertoire of potential therapeutics” against future outbreaks, said Ivelin Georgiev, PhD, director of the Vanderbilt Program in Computational Microbiology and Immunology and associate director of the Vanderbilt Institute for Infection, Immunology and Inflammation. “The pathogens keep evolving, and we’re basically playing catch-up.”



Georgiev says this antibody has “uncommon genetic and structural characteristics” that are different from other antibodies used to treat COVID-19.



LIBRA-seq was developed by 2019 by Ian Setliff, PhD, a former graduate student in Georgiev’s lab who now works in the biotechnology industry, and by Andrea Shiakolas, a current Vanderbilt graduate student.

[link to www.newschannel5.com (secure)]
“I’ve seen things you people wouldn’t believe. Attack ships on fire off the shoulder of Orion. I watched C-beams glitter in the dark near the Tannhäuser Gate.
All those moments will be lost in time, like tears in rain.
Time to die.”
~ Roy Batty, Blade Runner (1982)
Anonymous Coward
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09/23/2021 12:30 PM
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Re: Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses
Vanderbilts, Rothchilds, Rockefellers etc., never trust them, have tentacles everywhere
Constanttine  (OP)

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09/23/2021 12:33 PM

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Re: Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses
But Not to worry people. The FDA will put this antibody through all the most rigorous of trails. So we can expect to get this new treatment in about 12-15 years.
“I’ve seen things you people wouldn’t believe. Attack ships on fire off the shoulder of Orion. I watched C-beams glitter in the dark near the Tannhäuser Gate.
All those moments will be lost in time, like tears in rain.
Time to die.”
~ Roy Batty, Blade Runner (1982)
Constanttine  (OP)

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09/23/2021 12:35 PM

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Re: Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses
Vanderbilts, Rothchilds, Rockefellers etc., never trust them, have tentacles everywhere
 Quoting: Anonymous Coward 79781377


Vanderbilt is one of the greatest hospitals in the US. Not all researchers are enemies of humanity.
“I’ve seen things you people wouldn’t believe. Attack ships on fire off the shoulder of Orion. I watched C-beams glitter in the dark near the Tannhäuser Gate.
All those moments will be lost in time, like tears in rain.
Time to die.”
~ Roy Batty, Blade Runner (1982)
Constanttine  (OP)

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09/23/2021 12:37 PM

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Re: Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses
The research was supported in part by National Institutes of Health grants AI131722, AI157155, AI127521 and AI095202, the Hays Foundation COVID-19 Research Fund, the Dolly Parton COVID-19 Research Fund at Vanderbilt, Fast Grants, the Welch Foundation and the Mercatus Center of George Mason University.

One of the developers Ian Setliff
Regeneron · Molecular Profiling
PhD

Ivelin Georgiev is Bulgarian born. By the picture of him he is no older than 35. Quite impressive.
“I’ve seen things you people wouldn’t believe. Attack ships on fire off the shoulder of Orion. I watched C-beams glitter in the dark near the Tannhäuser Gate.
All those moments will be lost in time, like tears in rain.
Time to die.”
~ Roy Batty, Blade Runner (1982)
Constanttine  (OP)

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09/23/2021 12:40 PM

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Re: Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses
Can someone please karma pin this for info.
Thank you in advance hf
“I’ve seen things you people wouldn’t believe. Attack ships on fire off the shoulder of Orion. I watched C-beams glitter in the dark near the Tannhäuser Gate.
All those moments will be lost in time, like tears in rain.
Time to die.”
~ Roy Batty, Blade Runner (1982)
Constanttine  (OP)

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09/23/2021 12:42 PM

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Re: Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses
Headline : Vanderbilt University lab burns to ground. All researchers unfortunately were not able to escape.

Wouldn’t put anything past them. Disclaimer for those that can’t read sarcasm: not a real headline. :D
“I’ve seen things you people wouldn’t believe. Attack ships on fire off the shoulder of Orion. I watched C-beams glitter in the dark near the Tannhäuser Gate.
All those moments will be lost in time, like tears in rain.
Time to die.”
~ Roy Batty, Blade Runner (1982)
wattsun

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09/23/2021 12:42 PM
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Re: Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses
Vanderbilt University Medical Center says technology it developed has led to the discovery of an “ultra-potent” monoclonal antibody against COVID-19 and variants, including delta.



VUMC made the announcement Wednesday, saying the antibody can neutralize against SARS-CoV-2, the virus behind COVID-19. The research was published in “Cell Reports” earlier this month.



Researchers explain the technology behind the discovery is called LIBRA-seq, or Linking B-cell Receptor to Antigen Specificity through sequencing. It helped speed up the discovery.



“This is one way to proactively build a repertoire of potential therapeutics” against future outbreaks, said Ivelin Georgiev, PhD, director of the Vanderbilt Program in Computational Microbiology and Immunology and associate director of the Vanderbilt Institute for Infection, Immunology and Inflammation. “The pathogens keep evolving, and we’re basically playing catch-up.”



Georgiev says this antibody has “uncommon genetic and structural characteristics” that are different from other antibodies used to treat COVID-19.



LIBRA-seq was developed by 2019 by Ian Setliff, PhD, a former graduate student in Georgiev’s lab who now works in the biotechnology industry, and by Andrea Shiakolas, a current Vanderbilt graduate student.

[link to www.newschannel5.com (secure)]
 Quoting: Constanttine


Fauci sponsered school
wattsun
Constanttine  (OP)

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09/23/2021 12:48 PM

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Re: Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses
Can you read?!

Fauci will stomp this one down. This will never get out to the public.
“I’ve seen things you people wouldn’t believe. Attack ships on fire off the shoulder of Orion. I watched C-beams glitter in the dark near the Tannhäuser Gate.
All those moments will be lost in time, like tears in rain.
Time to die.”
~ Roy Batty, Blade Runner (1982)
Constanttine  (OP)

User ID: 78327618
Canada
09/23/2021 12:55 PM

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Re: Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses
bump
“I’ve seen things you people wouldn’t believe. Attack ships on fire off the shoulder of Orion. I watched C-beams glitter in the dark near the Tannhäuser Gate.
All those moments will be lost in time, like tears in rain.
Time to die.”
~ Roy Batty, Blade Runner (1982)
Anonymous Coward (OP)
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09/23/2021 02:21 PM
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Re: Vanderbilt: Discovery of ‘ultra-potent’ antibody could help with COVID, other viruses
bump
 Quoting: Constanttine





GLP