Nicotine appears to have addictive properties. However, nicotine is also a great synapse connector. The issue, heretofore, has been that at the same time its helping you, it's also killing you through smoke inhalation.

Nicotine itself seems to have no adverse effects on the body accept for opioid addiction.

However, the old remedy for Opium or the tobacco habit was Datura tincture. I wonder what would happen if you mixed trace amounts of Datura in with a regimented nicotiana dose.