A recent scientific paper was published 'Ivermectin, a potential anticancer drug derived from an antiparasitic drug

Ivermectin, a potential anticancer drug derived from an antiparasitic drug

[link to www.ncbi.nlm.nih.gov (secure)]

Graphical abstract
Ivermectin has powerful antitumor effects, including the inhibition of proliferation, metastasis, and angiogenic activity, in a variety of cancer cells. This may be related to the regulation of multiple signaling pathways by ivermectin through PAK1 kinase. On the other hand, ivermectin promotes programmed cancer cell death, including apoptosis, autophagy, and pyroptosis. Ivermectin induces apoptosis and autophagy is mutually regulated. Interestingly, ivermectin can also inhibit tumor stem cells and reverse multidrug resistance, and exerts the optimal effect when used in combination with other chemotherapy drugs.