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FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects
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S-man |
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Note this is just a FRAGMENT of the spike. (The 2-Proline stabilization will NOT help when the spike gets chewed up by enyzmes..this fragment will cause amyloid on its own) [ link to www.biorxiv.org (secure)] SARS-COV-2 Spike Protein Fragment eases Amyloidogenesis of Alpha-Synuclein"we show that the fragment FKNIDGYFKI of the spike protein, which is unique for SARS-COV-2, shifts preferentially the ensemble of alpha-synuclein monomer towards rod-like fibril seeding conformations"Amyloidogenic Sequence is at 194-FKNIDGYFKI-202 ================================================ NOTE: WALTZ Algo does show amyloidogenic region at locus ~200. [ link to ibb.co (secure)] ------ ps Hi Wordsworth...I just read "Character of the Happy Warrior" by your namesake, and it reminded me of you :)
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