Rejuvenation Research: Can Infusions of “Young” Blood Increase Lifespan? or what people have been saying here for years

A new study finds that young blood did not significantly improve the lifespan of old mice. However, old blood significantly decreased the lifespan of young mice.


In a new study, young and old mice were surgically joined such that they shared blood circulation for three months. According to the results, the old mice did not significantly benefit in terms of lifespan. On the other hand, the young mice that were exposed to blood from old animals had significantly decreased lifespan compared to mice that shared blood with other young mice. The study was published on July 22 in the peer-reviewed journal Rejuvenation Research.

Rejuvenation Research Journal
Research on rejuvenation therapies in the laboratory and clinic. Credit: Mary Ann Liebert, Inc., publishers


Heterochronic parabiosis is a research tool that is used to assess the effect of organs and of blood-borne factors on young and old animals. Less controlled than direct blood exchange, parabiosis is a model of blood sharing between two surgically connected animals. Iryna Pishel, from Kyiv National Taras Shevchenko University and Bienta Ltd, in Kyiv, Ukraine, and coauthors used heterochronic parabiosis between young and old mice and the isochronic controls for three months. Then they disconnected the animals and studied the effects of being joined on the blood plasma and animal lifespan.

“The most robust and interesting result of this study is the fact of a significant decrease in the lifespan of young mice from heterochronic parabiotic pairs,” state the investigators. “These data support our assumption that old blood contains factors capable of inducing aging in young animals. Finding and selective suppression of aging factor production in the organism could be the key research field for life extension,” they conclude.

Editor-in-Chief Irina Conboy, PhD, Professor, College of Engineering, University of California, Berkeley says “This work clarifies the question of whether the young blood or old blood control longevity, which has been debated (Nature 2005, Conboy, et. al)




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or what we have been saying select people have been doign for years!!!!