Cosmic Death Fungus - General

NAC and bacteria biofilms

This is a key finding, as it indicates that a combination of NAC and an antibiotic could potentially be used as direct bladder irrigation to treat recurrent UTIs. Research has shown a reduction in symptom frequency and antibiotic usage when bladder irrigation is employed in the treatment regimen for chronic UTIs [43]. BECs undergo rapid shedding when infected [44], exposing the immature bladder epithelium to pathogenic infiltration and consequent formation of quiescent intracellular reservoirs [44]. As we demonstrated, NAC prevents bacterial cell invasion in vitro, this could potentially also reduce further dissemination of an infection during a UTI episode and prevent increased bacterial shedding during recurrent episodes. Our in vitro assay results on BEC cell lines validated previous in vivo and in vitro findings of epithelial cell invasion by uropathogens [20]. However, further investigations using in vivo UTI mouse models are required to identify if this invasion protection is exercised by NAC.
This study also showed that NAC degraded secreted and matrix-bound polysaccharides in a strain-dependent manner in the uropathogens tested. This finding has also been observed in other biofilm-forming pathogens, such as S. aureus MSSA and MRSA, P. aeruginosa, and Helicobacter pylori [32,45,46]. Degrading polysaccharides required for matrix formation could affect the adhesive properties of the matrix to a surface and subsequent robust biofilm formation [36], the characteristics of which are especially vital for bacterial survival in the urinary tract given the shear stress bacteria are exposed to by urine flow forces [47].
When given alone, many antibiotics prescribed for UTIs, including ciprofloxacin, fail to eliminate the intracellular uropathogenic burden in mouse models [48]. This has led to the suggestion that recurrent UTIs in patients potentially stem from intracellular quiescent reservoirs not eradicated by antibiotic therapy [48]. Biofilm formation is also induced in many bacterial species in the presence of antibiotics [49], suggesting a role in the upregulation of resistance factors [50]. Our study showed that not only is NAC effective in reducing these intracellular reservoirs such as within IBCs, but there was no antagonistic activity between NAC and ciprofloxacin. Combining NAC with ciprofloxacin enhanced bacterial killing during treatment. Thus, the combination of an antibiotic with a stable antioxidant such as NAC could be the most effective way to treat urinary tract infections and prevent their recurrence.
[link to www.mdpi.com (secure)]

NAC very significant

Recent research has investigated the effect of thiol antioxidants such as glutathione as an antibiofilm agent against ESKAPE pathogens [28]. Similarly, it has been established that N-acetylcysteine (NAC) plays a pivotal role in protecting cells from oxidative stress by neutralising free radicals and reacting with reactive oxygen species (ROS) [29]. The antibiofilm properties of NAC are also well established [18,30,31]. NAC acts as a potent antibiofilm agent alone and in combination with antibiotics such as fosfomycin and Augmentin against Staphylococcus aureus (methicillin-resistant and sensitive), E. coli, E. faecalis, P. aeruginosa, Burkholderia spp., and other species, including surface-associated biofilms [18,32,33,34]. A recent insightful study showed that NAC penetrates the biofilm matrix and kills bacteria within, resulting in an empty gel-like matrix [35]. The researchers postulated that NAC destroys bacterial cells by dissociating and acidifying the bacterial cytoplasm, thereby causing protein and DNA degradation [35]. At lower concentrations of around 2 g/L, NAC alone can inhibit E. coli biofilm synthesis by 20–40% [18], and it can affect biofilm viability in S. aureus MRSA and MSSA by over 90% at concentrations of 4 g/L [32].
NAC has been widely investigated as an adjuvant for antibiotic treatment of various infections such as chronic bronchitis, vascular-related catheter infections, and urinary tract infections [18,36]. However, it is currently unknown if NAC provides specific protection against UTIs in the bladder and whether it is effective against established bladder infections.
This study aimed to investigate the efficacy of NAC as an antibiofilm agent against clinical uropathogenic E. coli and E. faecalis (refer to Table 1 for isolates used), the ability of NAC to inhibit the infiltration of bladder epithelial cells by uropathogens and prevent subsequent intracellular biofilm formation, the cytotoxicity of NAC on BECs at its intrinsic pH, and the effect of bacterial inflammatory stimulation following the treatment of cells.

Read the first one too
Thread: Cosmic Death Fungus: This Is Pre Disclosure!

This doesnt sound very cosmic.

Mushroom spores are electron-dense and can survive in the vacuum of space. Additionally, their outer layer is actually metallic and of a purple hue, which naturally allows the spore to deflect ultraviolet light. And as if all this wasn’t unique enough, the outer shell of the spore is the hardest organic compound to exist in nature.

Sounds pretty 'cosmic' to me.

In your imagination. Where did you get that information? Where? About spores surviving in space? Can you cite any studies? Not that studies mean anything.

For newbies to thread, since it has been pinned, [link to boards.4channel.org (secure)] and it helps if you READ before asking q's. Lots of feedback from people already on protocol.

[link to www.explorebigsky.com (secure)]

pub. Nov 2015

"...Fungi build cell walls out of chitin, the same material that makes up the hard outer shells of insects and other arthropods..."

you VILL eat ze bugz !

my BSO had sediments and shoulda been shaken, noticed it towards the end ... fck

yeah, I already pointed out the chitin connection 1 or 2 pages back. That's eff all to do with my question. No proof about spores surviving in space. Only questions FFS.

OP, a few questions:

would substituting oregano oil for SF722 be more effective for extreme fungal illness (systemic fungemia)? Sf722 has 5-10x efficacy of oregano oil.

Will this deal with mold/mycotoxin hyper inflammatory reactivity? I'm part of a many mold injured communities and it seems almost all chronic diseases have mold as a part of their pathology?

mold/mycotoxins has the ability to completely shut down detox channels of the body, which lays down the soil for other pathogenic diseases to take root.

Op,

Why aren't the antifungals and anthelmintics (like most of the -Apple drugs) effective long term against this?

Dr. Perlmutter talks about this in his book Grain Brain. He suggests it is due to many people having an allergy to wheat, so when wheat production dropped, schizophrenia dropped, and vice versa.

This is interesting. Mold is certainly insidious, but I did not know it had the ability to shut down detox channels.

I've had mold illness from several places I've lived. I believe this protocol has been helping overcoming the residual effects of that mold exposure.

While SF722 may be more effective, one might consider it could detox one too rapidly if it is 5-10x more effective, and that a gentler approach may be better, especially if mold shuts down detox channels. Think of it as a marathon versus a sprint. Why would one want to completely overrun compromised detox channels?

A potent oregano oil like NOW brand is the direction I would take. It directly shuts down inflammation with its interaction with interleukins. It also works systemically against molds. It is one of the most studied antifungals due to the food industry, so we know the benefits clearly. Undecylenic acid is surely potent but doesn't carry the same list of benefits. Keep in mind OO also performs a repairative function, repairing the gut barrier and enhancing immune response.

As far as effectiveness over time, the only concern there are simple compounds which can be subject to horizontal gene transfer and adaptation. This would include fluconazole and other solitary compounds like ampB. There is no evidence of adaptability to more complex natural compounds. Some species are simply more resistant by nature by utilizing lipid/chitin encapsulation. Fungi like cryptococcus basically have their own mobile biofilm, but oregano oil is still lethal to these species by disrupting the membrane.

Here are some studies from 1 month before protocol and 3 months on Nac protocol and 5 weeks on maintenance later.
Im no sure if the protocol helped me but I like to think it did

https://imgur.com/a/kk7r1xV

Thanks for posting this, that is quite an improvement.

Out of curiosity, many in the past have reported minor heart palpitations just prior to major improvements. Have you experienced this?

Thanks again.

I might had but I don't remember , I did feel dizzy for a few days. Maybe my blood pressure was adjusting .

[link to www.researchgate.net (secure)]
Via Terence McKenna

Ardis was talking about how NAC creates Glutathione and how Glutathione inhibits Phosphodiesterase. You what that is? It is pure evil and I’ll drop the bomb tonight here.

Does the Death fungus produce foot fetish in men?

t makes sense since it has a better way to prolong it´s home by making the dumb human ingest more parasites and filthy things coming from the body of women.

Why in the name of god would a man want to fuck or lick one of filthiest parts of the human body?

a real man never kneels to women and kiss their feet

How is this experiment possible since we've never left the upper atmosphere or gone beyond the Van Allen Belt?

Ardis, heh.

Synthetic Snake Venom Phosphodiesterase that is in the air, water, and the jabs is inhibited by Glutathione, Cysteine, and Ascorbic Acids, and completely inhibited by 5mM EDTA.

[link to rumble.com (secure)]

Dr. Bryan Ardis and Health Ranger Mike Adams review their recent findings on synthetic animal venom proteins and the toxic radioactive contents of the C19 shots.

Last Edited by Nemesis8 on 11/03/2022 07:57 PM

Ardis is a chiropracter FFS. A sham doctor. GTF outta here! Of course there's venoms everywhere - they're in big pharmas synthetic toolkit. Like synthetic estrogen et al. They've not cracked God's toolkit. Intelligent Design's toolkit.

We have had mold enter our house from out of nowhere. It definitely seems intelligent and a bit insidious. Bleach has been working against it.
But yes, it has caused tiredness and lethargy, along with sinus and lung presence.
I've read that rh- people are more sensitive to molds while rh+ people are more sensitive to viruses.

Industrial mold remediating companies use MMS (chlorine dioxide) with high pressure spray wands. They seal the room off, leaving houseplants and fill the room for 30 seconds and it kills everything, but not the houseplants. Don't leave fido, miss meow, or anything in an aquarium in the room though! There are companies that have done massive libraries and other huge buildings.

Bleach does not kill the spores. Cloves do. Get a pack of whole cloves and boil them, leave to sit overnight then decant/strain into a spray bottle, Spray and wipe mold with the mixture. 50g of cloves should make 1 litre of spray.

Fauci, go brush up on your BS. You are being Deposed 11/23 in court.