For mRNA, Covid Vaccines Are Just the Beginning | |
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Anonymous Coward User ID: 84321048 United States 11/05/2022 01:56 PM Report Abusive Post Report Copyright Violation | For mRNA, Covid Vaccines Are Just the Beginning With clinical vaccine trials for everything from HIV to Zika, messenger RNA could transform medicine—or widen health care inequalities. [link to www.wired.com (secure)] KATALIN KARIKÓ NEVER intended to make vaccines. For years before the pandemic, the Hungarian-American biochemist had been working to realize the therapeutic potential of mRNA—first trying to create a synthetic version of the messenger molecule that wouldn’t trigger the body’s inflammatory response, and then, once she and colleague Drew Weissman had achieved that goal, trying to get the medical and scientific community to pay attention. She had envisioned the technology being used to treat those recovering from heart attacks and strokes. But it was the frantic race for a Covid vaccine that earned Karikó belated global recognition. The work she and her colleagues had done on mRNA provided the foundation for Moderna and BioNTech to quickly develop Covid vaccines that have now saved millions of lives. Traditional vaccines train the immune system by introducing it to harmless versions of whole viruses—the body learns to recognize the virus’s key features, such as SARS-CoV-2’s infamous spike protein. These new mRNA vaccines found a more elegant way to achieve the same goal, using messenger RNA—a genetic molecule found throughout nature that’s used to transmit information within and between cells—to provide the body with a set of instructions on how to make the spike protein itself, essentially borrowing the body’s internal machinery and turning it into a photocopier. This difference allowed mRNA vaccines to be designed, created, and approved in record time. Over the past 18 months, mRNA technology has been injected into billions of arms and has helped slow the devastating impact of the pandemic. But its long-term impact—accelerated by Covid—could be even greater. “It seems like the sky is the limit,” says Karikó. “Previously the belief was not there.” Dozens of clinical trials are now underway for new forms of the mRNA vaccine—targeting everything from malaria to Zika, herpes, and cytomegalovirus. Last month, Moderna—which was founded in 2014 to explore the potential of mRNA—announced it had started Phase I clinical trials for two mRNA-based HIV vaccines. “The timeline for what can be achieved using the mRNA platform is so much better,” says Carl Dieffenbach, director of the Division of AIDS at the US National Institutes of Health, who is overseeing those trials. There was some work on mRNA happening before the pandemic—Moderna had spent years on the lipid envelope that encases the strand of mRNA in the vaccine, for instance. “Like all overnight successes, mRNA has been in development for a long time,” says Richard Hatchett of the Coalition for Epidemic Preparedness Innovations (CEPI). The US Biomedical Advanced Research and Development Authority invested in an mRNA vaccine for Zika in 2016, but “the urgency sort of trailed off” as the outbreak subsided, Hatchett says. There had also been tentative attempts to develop mRNA platforms for other coronaviruses, such as MERS, work that proved crucial when Covid broke out. Moderna was able to tweak its MERS vaccine for the new disease, meaning its Covid vaccine entered clinical trials just 66 days after SARS-CoV-2’s genetic sequence was published. It’s true that mRNA vaccines would probably have come to market eventually, but they were on what Dieffenbach calls “a leisurely stroll.” Covid “pressure-tested” them—advancing their emergence by years or decades. Karikó remembers organizing the first mRNA conference in 2013 and says that nobody in attendance would have expected an FDA-approved product less than 10 years later. “Because of the success against Covid, we’re going to see tremendous investment, and we’re going to learn just how flexible it is and how finely we can target,” says Hatchett. One of mRNA’s strengths is its “remarkable agility,” as Hatchett puts it. Its only raw ingredients are the four nucleotides that form the “letters” of the RNA sequence, so it can be designed and made pretty rapidly. “Biological manufacturing is very hard and temperamental and has been difficult to introduce in many environments. It’s taken India decades to build up the vaccine manufacturing capability they have,” says Hatchett. “It may be easier for countries to develop an mRNA production capacity than traditional biological manufacturing capability.” Developing countries could, Hatchett suggests, leapfrog over traditional vaccine-manufacturing processes and go straight to mRNA—mRNA plants are already being planned in countries across Africa and Asia. After Covid, they could be quickly repurposed to create vaccines for other diseases—all you need to do is change the order of the bases in the mRNA to give the body a new set of instructions. There are also far fewer concerns about purity or contamination than with traditional vaccines—the body quickly translates, expresses, and breaks down the strand of mRNA. “mRNA is completely interchangeable,” says Jackie Miller, senior vice president for infectious diseases at Moderna. “What changes between the different vaccines is the DNA template that we utilize to synthesize the messenger RNA, but across all of our vaccine portfolio, we’re using the same lipid nanoparticle.” [@50% MORE AT LINK] [link to www.wired.com (secure)] Still experimental, event the manufacturer distrusts it and wont risk legal action. The jury is still out on Longterm Testing,,,18 months is not long term. More doctors are beginning to tell their pregnant moms to stop taking boosters A spike in unexplained deaths in age groups normally very healthy.... What ever happened to that requirement to keep the shot at a negative 85 degrees Celsius until put in your arm? That requirement was the big stumbling block for over 25 years keeping the technology from moving along..... hmmm ,,,not thoroughly tested for me. |
Anonymous Coward User ID: 84638619 United States 11/05/2022 01:56 PM Report Abusive Post Report Copyright Violation | For mRNA, Covid Vaccines Are Just the Beginning With clinical vaccine trials for everything from HIV to Zika, messenger RNA could transform medicine—or widen health care inequalities. [link to www.wired.com (secure)] KATALIN KARIKÓ NEVER intended to make vaccines. For years before the pandemic, the Hungarian-American biochemist had been working to realize the therapeutic potential of mRNA—first trying to create a synthetic version of the messenger molecule that wouldn’t trigger the body’s inflammatory response, and then, once she and colleague Drew Weissman had achieved that goal, trying to get the medical and scientific community to pay attention. She had envisioned the technology being used to treat those recovering from heart attacks and strokes. But it was the frantic race for a Covid vaccine that earned Karikó belated global recognition. The work she and her colleagues had done on mRNA provided the foundation for Moderna and BioNTech to quickly develop Covid vaccines that have now saved millions of lives. Traditional vaccines train the immune system by introducing it to harmless versions of whole viruses—the body learns to recognize the virus’s key features, such as SARS-CoV-2’s infamous spike protein. These new mRNA vaccines found a more elegant way to achieve the same goal, using messenger RNA—a genetic molecule found throughout nature that’s used to transmit information within and between cells—to provide the body with a set of instructions on how to make the spike protein itself, essentially borrowing the body’s internal machinery and turning it into a photocopier. This difference allowed mRNA vaccines to be designed, created, and approved in record time. Over the past 18 months, mRNA technology has been injected into billions of arms and has helped slow the devastating impact of the pandemic. But its long-term impact—accelerated by Covid—could be even greater. “It seems like the sky is the limit,” says Karikó. “Previously the belief was not there.” Dozens of clinical trials are now underway for new forms of the mRNA vaccine—targeting everything from malaria to Zika, herpes, and cytomegalovirus. Last month, Moderna—which was founded in 2014 to explore the potential of mRNA—announced it had started Phase I clinical trials for two mRNA-based HIV vaccines. “The timeline for what can be achieved using the mRNA platform is so much better,” says Carl Dieffenbach, director of the Division of AIDS at the US National Institutes of Health, who is overseeing those trials. There was some work on mRNA happening before the pandemic—Moderna had spent years on the lipid envelope that encases the strand of mRNA in the vaccine, for instance. “Like all overnight successes, mRNA has been in development for a long time,” says Richard Hatchett of the Coalition for Epidemic Preparedness Innovations (CEPI). The US Biomedical Advanced Research and Development Authority invested in an mRNA vaccine for Zika in 2016, but “the urgency sort of trailed off” as the outbreak subsided, Hatchett says. There had also been tentative attempts to develop mRNA platforms for other coronaviruses, such as MERS, work that proved crucial when Covid broke out. Moderna was able to tweak its MERS vaccine for the new disease, meaning its Covid vaccine entered clinical trials just 66 days after SARS-CoV-2’s genetic sequence was published. It’s true that mRNA vaccines would probably have come to market eventually, but they were on what Dieffenbach calls “a leisurely stroll.” Covid “pressure-tested” them—advancing their emergence by years or decades. Karikó remembers organizing the first mRNA conference in 2013 and says that nobody in attendance would have expected an FDA-approved product less than 10 years later. “Because of the success against Covid, we’re going to see tremendous investment, and we’re going to learn just how flexible it is and how finely we can target,” says Hatchett. One of mRNA’s strengths is its “remarkable agility,” as Hatchett puts it. Its only raw ingredients are the four nucleotides that form the “letters” of the RNA sequence, so it can be designed and made pretty rapidly. “Biological manufacturing is very hard and temperamental and has been difficult to introduce in many environments. It’s taken India decades to build up the vaccine manufacturing capability they have,” says Hatchett. “It may be easier for countries to develop an mRNA production capacity than traditional biological manufacturing capability.” Developing countries could, Hatchett suggests, leapfrog over traditional vaccine-manufacturing processes and go straight to mRNA—mRNA plants are already being planned in countries across Africa and Asia. After Covid, they could be quickly repurposed to create vaccines for other diseases—all you need to do is change the order of the bases in the mRNA to give the body a new set of instructions. There are also far fewer concerns about purity or contamination than with traditional vaccines—the body quickly translates, expresses, and breaks down the strand of mRNA. “mRNA is completely interchangeable,” says Jackie Miller, senior vice president for infectious diseases at Moderna. “What changes between the different vaccines is the DNA template that we utilize to synthesize the messenger RNA, but across all of our vaccine portfolio, we’re using the same lipid nanoparticle.” [@50% MORE AT LINK] [link to www.wired.com (secure)] why is covid vaccines being posted here.. mRNA is NOT A VACCINE... stop with it. It programs your killer T cells to recognise the so called spike proteins which are NOT spikes... to recognize all the coronas NON SPIKE stuff.. its all the same.. and take all corona out.. What is that so fucking hard to comprehend. |
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Catellite
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Anonymous Coward User ID: 84617438 Canada 11/05/2022 02:15 PM Report Abusive Post Report Copyright Violation | "Over the past 18 months, mRNA technology has been injected into billions of arms and has helped slow the devastating impact of the pandemic." Quoting: Mojo Rysen FUCK YOU TARD. You're a FUCKING IDIOT. What pandemic? I dont know anyone who was sick or died. None of my friends, family or coworkers know of anyone who was sick or died. None of their friends or families or coworkers know of anyone who was sick or died. That is, until they started injecting people. The moment they started "vaccinating", thats when I knew of people who were dying and getting sick. And the more they injected, the more sick and dying I knew. Before that, none at all. |
Anonymous Coward User ID: 84321048 United States 11/05/2022 02:21 PM Report Abusive Post Report Copyright Violation | "Over the past 18 months, mRNA technology has been injected into billions of arms and has helped slow the devastating impact of the pandemic." Quoting: Mojo Rysen FUCK YOU TARD. You're a FUCKING IDIOT. What pandemic? I dont know anyone who was sick or died. None of my friends, family or coworkers know of anyone who was sick or died. None of their friends or families or coworkers know of anyone who was sick or died. That is, until they started injecting people. The moment they started "vaccinating", thats when I knew of people who were dying and getting sick. And the more they injected, the more sick and dying I knew. Before that, none at all. 14,000 senior citizens died from Covid when Governor Cuomo housed infected individuals in nursing homes throughout NY so he could payback his big money donors who run nursing homes. Covid is a disease....a man made one but it is real. |
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Rabbi Chaim Finklestein User ID: 83812061 Romania 11/05/2022 02:26 PM Report Abusive Post Report Copyright Violation | |
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Anonymous Coward User ID: 83995243 Germany 11/05/2022 02:33 PM Report Abusive Post Report Copyright Violation | Programming the human body will be the next computers/internet craze. For the next gen not having mRNA tech would be the same as ours when we see someone without a cellphone.. Strange times ahead. |
Anonymous Coward User ID: 84401887 New Zealand 11/05/2022 02:37 PM Report Abusive Post Report Copyright Violation | So covid mRNA vaxx causes cancer and myocarditis, so they make new vaxx to solve the cancer and myocarditis, what new problems will the new vaxx cause? What's going to happen to all those Lipid Nano particles transporting the RNA? That's just going to keep build up causing more and more problems, And these things are toxic af. Go and read the phizer saftey report on the covid vaxx. They didn't bother doing carcinogenic or toxicity studies on the vaxx. Seems like mRNA jabbs were designed to be subscription service type of tech, where the solve one problem and create 5 more requiring more solutions. They are going to try profit on the democide of billions humans. |
KatMathisMusic
User ID: 84627155 Mexico 11/05/2022 02:39 PM Report Abusive Post Report Copyright Violation | My brother (who lived in England) died suddenly after taking the vaccine for work. He was only 58 and perfectly healthy. Worked in construction his whole life then dropped dead 2 weeks after the jab of a massive heart attack. Kat Mathis Singer, Songwriter, Patriot! NEW SONG CHILDREN ARE SWEET Watch the video here! [link to www.youtube.com (secure)] I want to use my music to help Red Pill those who are on the edge, and to entertain and encourage those who already see the truths. Thank you for supporting! |
TerraFirma's Esoterrorist
User ID: 83924675 United States 11/05/2022 02:41 PM Report Abusive Post Report Copyright Violation | Different mRNA shot...but all bring the same outcome disaster. Thread: BOMBSHELL: MAN in 2013 TRIAL WITH 200K PEOPLE TO TEST MRNA-BASED MEDICATION, less than 5 alive! [link to www.bitchute.com (secure)] Last Edited by TerraFirma's Esoterrorist on 11/05/2022 02:42 PM "Keep a weather eye to the chart on high and go home another way" –James Taylor Never Die Young |
Anonymous Coward User ID: 78871954 Mexico 11/05/2022 02:43 PM Report Abusive Post Report Copyright Violation | My brother (who lived in England) died suddenly after taking the vaccine for work. He was only 58 and perfectly healthy. Worked in construction his whole life then dropped dead 2 weeks after the jab of a massive heart attack. Quoting: KatMathisMusic Im sorry for your loss. Its very very depressing whats going on with this whole debacle. Also what part of mexico you from friend. |
Anonymous Coward User ID: 73289669 United States 11/05/2022 02:49 PM Report Abusive Post Report Copyright Violation | For mRNA, Covid Vaccines Are Just the Beginning With clinical vaccine trials for everything from HIV to Zika, messenger RNA could transform medicine—or widen health care inequalities. [link to www.wired.com (secure)] KATALIN KARIKÓ NEVER intended to make vaccines. For years before the pandemic, the Hungarian-American biochemist had been working to realize the therapeutic potential of mRNA—first trying to create a synthetic version of the messenger molecule that wouldn’t trigger the body’s inflammatory response, and then, once she and colleague Drew Weissman had achieved that goal, trying to get the medical and scientific community to pay attention. She had envisioned the technology being used to treat those recovering from heart attacks and strokes. But it was the frantic race for a Covid vaccine that earned Karikó belated global recognition. The work she and her colleagues had done on mRNA provided the foundation for Moderna and BioNTech to quickly develop Covid vaccines that have now saved millions of lives. Traditional vaccines train the immune system by introducing it to harmless versions of whole viruses—the body learns to recognize the virus’s key features, such as SARS-CoV-2’s infamous spike protein. These new mRNA vaccines found a more elegant way to achieve the same goal, using messenger RNA—a genetic molecule found throughout nature that’s used to transmit information within and between cells—to provide the body with a set of instructions on how to make the spike protein itself, essentially borrowing the body’s internal machinery and turning it into a photocopier. This difference allowed mRNA vaccines to be designed, created, and approved in record time. Over the past 18 months, mRNA technology has been injected into billions of arms and has helped slow the devastating impact of the pandemic. But its long-term impact—accelerated by Covid—could be even greater. “It seems like the sky is the limit,” says Karikó. “Previously the belief was not there.” Dozens of clinical trials are now underway for new forms of the mRNA vaccine—targeting everything from malaria to Zika, herpes, and cytomegalovirus. Last month, Moderna—which was founded in 2014 to explore the potential of mRNA—announced it had started Phase I clinical trials for two mRNA-based HIV vaccines. “The timeline for what can be achieved using the mRNA platform is so much better,” says Carl Dieffenbach, director of the Division of AIDS at the US National Institutes of Health, who is overseeing those trials. There was some work on mRNA happening before the pandemic—Moderna had spent years on the lipid envelope that encases the strand of mRNA in the vaccine, for instance. “Like all overnight successes, mRNA has been in development for a long time,” says Richard Hatchett of the Coalition for Epidemic Preparedness Innovations (CEPI). The US Biomedical Advanced Research and Development Authority invested in an mRNA vaccine for Zika in 2016, but “the urgency sort of trailed off” as the outbreak subsided, Hatchett says. There had also been tentative attempts to develop mRNA platforms for other coronaviruses, such as MERS, work that proved crucial when Covid broke out. Moderna was able to tweak its MERS vaccine for the new disease, meaning its Covid vaccine entered clinical trials just 66 days after SARS-CoV-2’s genetic sequence was published. It’s true that mRNA vaccines would probably have come to market eventually, but they were on what Dieffenbach calls “a leisurely stroll.” Covid “pressure-tested” them—advancing their emergence by years or decades. Karikó remembers organizing the first mRNA conference in 2013 and says that nobody in attendance would have expected an FDA-approved product less than 10 years later. “Because of the success against Covid, we’re going to see tremendous investment, and we’re going to learn just how flexible it is and how finely we can target,” says Hatchett. One of mRNA’s strengths is its “remarkable agility,” as Hatchett puts it. Its only raw ingredients are the four nucleotides that form the “letters” of the RNA sequence, so it can be designed and made pretty rapidly. “Biological manufacturing is very hard and temperamental and has been difficult to introduce in many environments. It’s taken India decades to build up the vaccine manufacturing capability they have,” says Hatchett. “It may be easier for countries to develop an mRNA production capacity than traditional biological manufacturing capability.” Developing countries could, Hatchett suggests, leapfrog over traditional vaccine-manufacturing processes and go straight to mRNA—mRNA plants are already being planned in countries across Africa and Asia. After Covid, they could be quickly repurposed to create vaccines for other diseases—all you need to do is change the order of the bases in the mRNA to give the body a new set of instructions. There are also far fewer concerns about purity or contamination than with traditional vaccines—the body quickly translates, expresses, and breaks down the strand of mRNA. “mRNA is completely interchangeable,” says Jackie Miller, senior vice president for infectious diseases at Moderna. “What changes between the different vaccines is the DNA template that we utilize to synthesize the messenger RNA, but across all of our vaccine portfolio, we’re using the same lipid nanoparticle.” [@50% MORE AT LINK] [link to www.wired.com (secure)] And now you understand the real reason for all this... What if I told you that many of even the off the wall conspiracy theories have a grain of truth to them? Project looking glass for instance.... It is an AI future projection model program... Think hurricane spaghetti models and how accurate they have become lately then think of an even larger system capable of running thousands of simulations to predict a future trend in society, politics and economics... Well what if I told you it is true that those models in deed did ultimately always predict a single event in the future that was virtually inescapable but it wasn't some mass awakening or expansion of consciousness... It was self destruction of the human race due to the current advancement of AI and Bio technology... It showed that this new knowledge could not be controlled in our current societies, the Jeanie could not be put back in the bottle and unlike nuclear weapons fissile material there is no one part of a system that could be tightly controlled to keep the crazies from getting ahold of it and no way to combat what is comming... Not unless the society were changed, not unless systems were put in place to tightly control and surveil all of society... Not unless some type of rapid production easily genetically modified vaccine type could be created and the infrastructure to mass produce it already be in place.... Now, let your own imagination inject this bit of information in to everything we have seen in the last two years and see if it makes more sense to you now. |
Anonymous Coward User ID: 84617438 Canada 11/05/2022 02:51 PM Report Abusive Post Report Copyright Violation | "Over the past 18 months, mRNA technology has been injected into billions of arms and has helped slow the devastating impact of the pandemic." Quoting: Mojo Rysen FUCK YOU TARD. You're a FUCKING IDIOT. What pandemic? I dont know anyone who was sick or died. None of my friends, family or coworkers know of anyone who was sick or died. None of their friends or families or coworkers know of anyone who was sick or died. That is, until they started injecting people. The moment they started "vaccinating", thats when I knew of people who were dying and getting sick. And the more they injected, the more sick and dying I knew. Before that, none at all. 14,000 senior citizens died from Covid when Governor Cuomo housed infected individuals in nursing homes throughout NY so he could payback his big money donors who run nursing homes. Covid is a disease....a man made one but it is real. Nursing homes. You mean the places when they pump people full of meds and chemicals right? Are you sure they died of some disease, and not from an extra few doses here an extra few doses there. Noooo, that can never happen. Impossible. No such thing as COVID. It was influenza. It was always influenza. They simple rebranded it. Stop doing influenza A and B tests, claimed the flu disappeared magically for 2 years, refused to test anyone for influenza and hyped a fake scamdemic. |
Anonymous Coward User ID: 83062514 Spain 11/05/2022 02:51 PM Report Abusive Post Report Copyright Violation | mRNA has potential for future treatments of things like cancer. Imagine creating mRNA that can cause cancer cells and only cancer cells to self destruct? That would be a lot safer than chemo Quoting: Anonymous Coward 84599932 *mRNA is unstable. Maybe mRNA had* potential for future treatments of things like cancer, but as of now? Only the jabbed will trust it, and even those numbers will fall over time as they die. Nobody who avoided it will ever trust mRNA. Those that trusted and took any jabs won’t be around long enough for any research to pan out. *mRNA is unstable. It had financial potential to be used in treating (killing) cancer patients. But now, it will only see its morbidly profitable fruits in the already jabbed. |
XJDUB
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AlMassih
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Anonymous Coward User ID: 55301936 United States 11/05/2022 03:29 PM Report Abusive Post Report Copyright Violation | mRNA has potential for future treatments of things like cancer. Imagine creating mRNA that can cause cancer cells and only cancer cells to self destruct? That would be a lot safer than chemo Quoting: Anonymous Coward 84599932 I’m talking about future potential mRNA technology, but current ‘vaccines’ Oh,so you actually believe that they want to cure cancer, the huge money maker for them? Yeah, right sure they do. There's already been several safe ways to cure cancer for years now. Those methods have been completely suppressed, like many other things that would be a benefit to us. Get real, any mRNA technology is going to be used for bad purposes where it concerns us anyway. |
Anonymous Coward User ID: 39907610 United Kingdom 11/05/2022 03:33 PM Report Abusive Post Report Copyright Violation | "Over the past 18 months, mRNA technology has been injected into billions of arms and has helped slow the devastating impact of the pandemic." Quoting: Mojo Rysen FUCK YOU TARD. You're a FUCKING IDIOT. What pandemic? I dont know anyone who was sick or died. None of my friends, family or coworkers know of anyone who was sick or died. None of their friends or families or coworkers know of anyone who was sick or died. That is, until they started injecting people. The moment they started "vaccinating", thats when I knew of people who were dying and getting sick. And the more they injected, the more sick and dying I knew. Before that, none at all. This for sure |
RegalBeast
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