Somebody tell him, “thank you, Sir.” | |
Massimo User ID: 78325790 United States 11/28/2022 02:05 PM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 84837144 11/28/2022 02:38 PM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 81919318 United States 11/28/2022 02:42 PM Report Abusive Post Report Copyright Violation | Excerpt from Pg. 12: "Regarding the nose-to-brain focused study, the effect of GO sheet lateral dimension on the extent of translocation was investigated. GO sheet lateral dimension was inversely related to extent to which GO sheets could translocate from the nose to the brain following intranasal administration, with the GO sheets of lowest lateral dimensions translocating to the greatest extent. A fraction of the translocated GO sheets was seen to diffuse to distal regions of the brain past the initially encountered olfactory bulb." Glad I never got a "nasal swab!" |
Reaching
User ID: 83952874 United States 11/28/2022 02:47 PM Report Abusive Post Report Copyright Violation | So I read the Abstract, some of the meat of the study, the Summary, and the Conclusion. The good news is that graphene oxide (GO) degrades over time, beginning in just days;, but taking as much as a year m/l, depending on a number of factors, but most importantly dependent on which organ/s the GO primarily resides. The spleen appears to be the major store house of the GO; there, it has a longer period of time to degrade. The GO also breaks the barrier from the olfactory/inhalation of the material into the back of the brain area, where it continues to degrade 9-months < out. My take, on the little that I read of the study, is if people refrain from getting vaxx boosters, the body has a fighting chance. IMO, the GO blood-clots may be the bodies attempt to control and flush the invasive GO materials; but flush to where? Perhaps, if given enough time, the body will continue to degrade the invasive material from the whole of the body; however, suffering multiple and large sized clots in the body may preclude having enough time to do the noble work of degrading the GO. NOTE: The study was done on mice. Who knows if Big Pharma-Big Medicine (aka Medical Mafia) has done any studies/autopsies on humans. |
Anonymous Coward User ID: 81919318 United States 11/28/2022 02:52 PM Report Abusive Post Report Copyright Violation | 5 STARS! Important post! I saved [link to www.research.manchester.ac.uk (secure)] on my computer to be sure I can read al of it before someone tries to scrub it off the internet. Looks like a goldmine of information. Even the Table of Contents is interesting. This is from Pg. 3: 2.5. Chemically mediated degradation. .................................................................... 36 2 2.5.1. Overview of chemical mediated CNM degradation and the lessons learnt. ...................................................................................................................... 42 2.6. Enzyme catalysed biodegradation. ................................................................... 46 2.6.1. The peroxidase enzyme superfamily. ......................................................... 46 2.6.2. Horse radish peroxidase. ............................................................................ 46 2.6.3. Myeloperoxidase.......................................................................................... 51 2.6.4. Other enzymes. ............................................................................................ 54 2.6.5. Overview of enzyme mediated CNM biodegradation and the lessons learnt. ...................................................................................................................... 57 2.7. Biodegradation mediated by cells. .................................................................... 61 2.7.1. Neutrophils................................................................................................... 61 2.7.2. Macrophages................................................................................................ 65 2.7.3. Microglia. ...................................................................................................... 67 2.7.4. Overview of cell mediated CNM biodegradation and the lessons learnt. 71 2.8. Biodegradation of CNMs in vivo. ....................................................................... 76 2.8.1. Biodegradation of CNMs in the lungs. ....................................................... 76 2.8.2. Biodegradation of CNMs in other tissues. ................................................. 79 2.8.3. Overview of in vivo mediated CNM biodegradation and the lessons learnt. ...................................................................................................................... 80 2.8.4. Summary of the factors that can be used to modulate CNMs biodegradation relevant to biomedicine................................................................... 84 2.9. Products of degradation and their health effects. ............................................ 84 |
Anonymous Coward User ID: 81919318 United States 11/28/2022 03:01 PM Report Abusive Post Report Copyright Violation | pg. 46 "2.6.2. Horse radish peroxidase. The horse radish peroxidase (HRP) enzyme, which contains an Fe catalytic core, was the first enzyme piloted to prove the enzyme-catalysed biodegradability of CNMs. Allen et al. conducted the initial study that described how carboxylated SWNTs can be biodegraded pg. 47 "over 12 weeks at 4°C by the oxidative action of HRP in the presence of low concentrations (800 μM) of H2O2.95 The high redox potential of HRP Compound I/ Compound II cycle in the presence of H2O2 was responsible for the efficient catalysis of the oxidative biodegradation. Low concentrations of either Fe or H2O2 applied alone were insufficient to produce the same biodegradation kinetics, indicative of the importance of the enzyme protein structure, particularly the active site. The authors completed a follow-up study in which the same experiment was completed over 10 days at 25°C.96 Biodegradation occurred with more rapid kinetics at the higher temperature." 37°C = 98.6°F, so at human body temperature it might work even faster. |
Anonymous Coward User ID: 79002322 United States 11/28/2022 03:08 PM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 81919318 United States 11/28/2022 03:28 PM Report Abusive Post Report Copyright Violation | pg. 50 "In this study, when the intrinsically defected GO sheets were non-covalently coated with polyethylene glycol (PEG) or bovine serum albumin, their biodegradation kinetics were significantly attenuated compared to the uncoated GO sheets. It is possible that the coatings provided non-specific shielding of the surface of GO sheets from the enzymes as previously described in NaClO mediated CNM degradation86. In order to exploit this, GO sheets were functionalised with PEG via a disulphide bridge102. As expected, these constructs demonstrated poor biodegradation kinetics in the presence of just HRP and H2O2. However, upon cleavage of the disulphide bridge using a reducing agent (to mimic the reductive intracellular environment) the PEG groups were released and the GO sheets underwent facile HRP mediated biodegradation over 4 days.102" PEG is in the Covid shots, so that makes the graphene oxide more difficult to biodegrade with Horse radish and Hydrogen Peroxide. Hmmm....I wonder what the reducing agent is that is mentioned above. |
Anonymous Coward User ID: 81919318 United States 11/28/2022 03:47 PM Report Abusive Post Report Copyright Violation | Pg. 60 "Maximum DNA damage was induced by degradation products obtained on day 7 of HRP mediated degradation of SWNT. HRP is from horse radish. I'm speed reading this stuff without fully understanding it, but I don't thing graphene oxide has DNA, so the DNA damage they are referring to might be to the human. Uh oh! |
Anonymous Coward User ID: 78147659 United States 11/28/2022 04:11 PM Report Abusive Post Report Copyright Violation | |
Deplorable Zenobia
User ID: 84299709 United States 11/28/2022 04:27 PM Report Abusive Post Report Copyright Violation | so I can come back to later. This is what makes this the best cyber bar in the Universe! Thx, OP! And thought struggles against the results, trying to avoid those unpleasant results while keeping on with that way of thinking. That is what I call 'sustained incoherence.' ...David Bohm “How, O Zenobia, hast thou dared to insult Roman emperors?” ...Aurelian, 44th Emperor of the Roman Empire |
~o00O00oo; )
(OP) User ID: 81898348 United States 11/28/2022 05:51 PM Report Abusive Post Report Copyright Violation | |
~o00O00oo; )
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Base12
User ID: 78222180 United States 11/28/2022 06:13 PM Report Abusive Post Report Copyright Violation | Visit my website... [link to www.mostholyplace.com] |
Anonymous Coward User ID: 77454925 United States 11/28/2022 07:21 PM Report Abusive Post Report Copyright Violation | |