Pfizer Responds!! | |
Anonymous Coward User ID: 19145374 United States 01/28/2023 03:04 AM Report Abusive Post Report Copyright Violation | 1. When I worked at Bayer, they got around regulations on "genetically modified" pesticide biologics by performing so-called "encouraged evolution" to achieve a desired mutation. Similar to how Pfizer is performing "directed evolution" to avoid calling it "gain of function." Quoting: Happy in Nature 2. But these "encouraged" or "directed" "evolution" methods are actually more dangerous than straightforward genetic modification, because the mutations are not precisely targeted. They mutate the ENTIRE genomes with mutagens and what they produce is much more unpredictable. 3. These "evolutionary" methods to create mutants are not done because they're less dangerous to humans. It's done because it's less LEGALLY dangerous, has fewer costly regulations to circumvent, and has less social stigma associated with it. That's all. 4. This was always fully acknowledged within the company. Meanwhile the Left-wing protesters went and protested Monsanto down the street because they were producing evil "genetically modified" plants and pesticides, while we were spared because we did "encouraged evolution." [link to twitter.com (secure)] https://twitter.com/_/status/1618493887961763840 Now THIS is interesting! |
Anonymous Coward User ID: 80382180 United States 01/28/2023 03:14 AM Report Abusive Post Report Copyright Violation | |
16 Blocks
User ID: 76669567 Germany 01/28/2023 03:22 AM Report Abusive Post Report Copyright Violation | New York, N.Y., January 27, 2023 – Allegations have recently been made related to gain of function and directed evolution research at Pfizer and the company would like to set the record straight. Quoting: Happy in Nature In the ongoing development of the Pfizer-BioNTech COVID-19 vaccine, Pfizer has not conducted gain of function or directed evolution research. Working with collaborators, we have conducted research where the original SARS-CoV-2 virus has been used to express the spike protein from new variants of concern. This work is undertaken once a new variant of concern has been identified by public health authorities. This research provides a way for us to rapidly assess the ability of an existing vaccine to induce antibodies that neutralize a newly identified variant of concern. We then make this data available through peer reviewed scientific journals and use it as one of the steps to determine whether a vaccine update is required. In addition, to meet U.S. and global regulatory requirements for our oral treatment, PAXLOVID™, Pfizer undertakes in vitro work (e.g., in a laboratory culture dish) to identify potential resistance mutations to nirmatrelvir, one of PAXLOVID’s two components. With a naturally evolving virus, it is important to routinely assess the activity of an antiviral. Most of this work is conducted using computer simulations or mutations of the main protease–a non-infectious part of the virus. In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells. In addition, in vitro resistance selection experiments are undertaken in cells incubated with SARS-CoV-2 and nirmatrelvir in our secure Biosafety level 3 (BSL3) laboratory to assess whether the main protease can mutate to yield resistant strains of the virus. It is important to note that these studies are required by U.S. and global regulators for all antiviral products and are carried out by many companies and academic institutions in the U.S. and around the world. Fact-based information rooted in sound science is vitally important to overcoming the COVID-19 pandemic and Pfizer remains committed to transparency and helping alleviate the devastating burden of this disease. [link to www.pfizer.com (secure)] Scroll down to safety information and side effects that include myocarditis and pericarditis. Most of this work is conducted using computer simulations or mutations of the main protease–a non-infectious part of the virus. In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells. In addition, in vitro resistance selection experiments are undertaken in cells incubated with SARS-CoV-2 and nirmatrelvir in our secure Biosafety level 3 (BSL3) laboratory to assess whether the main protease can mutate to yield resistant strains of the virus. Emotion beats reason Don't let it be that way |
led_Dis_Spencer
User ID: 67980327 United States 01/28/2023 03:28 AM Report Abusive Post Report Copyright Violation | New York, N.Y., January 27, 2023 – Allegations have recently been made related to gain of function and directed evolution research at Pfizer and the company would like to set the record straight. Quoting: Happy in Nature In the ongoing development of the Pfizer-BioNTech COVID-19 vaccine, Pfizer has not conducted gain of function or directed evolution research. Working with collaborators, we have conducted research where the original SARS-CoV-2 virus has been used to express the spike protein from new variants of concern. This work is undertaken once a new variant of concern has been identified by public health authorities. This research provides a way for us to rapidly assess the ability of an existing vaccine to induce antibodies that neutralize a newly identified variant of concern. We then make this data available through peer reviewed scientific journals and use it as one of the steps to determine whether a vaccine update is required. In addition, to meet U.S. and global regulatory requirements for our oral treatment, PAXLOVID™, Pfizer undertakes in vitro work (e.g., in a laboratory culture dish) to identify potential resistance mutations to nirmatrelvir, one of PAXLOVID’s two components. With a naturally evolving virus, it is important to routinely assess the activity of an antiviral. Most of this work is conducted using computer simulations or mutations of the main protease–a non-infectious part of the virus. In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells. In addition, in vitro resistance selection experiments are undertaken in cells incubated with SARS-CoV-2 and nirmatrelvir in our secure Biosafety level 3 (BSL3) laboratory to assess whether the main protease can mutate to yield resistant strains of the virus. It is important to note that these studies are required by U.S. and global regulators for all antiviral products and are carried out by many companies and academic institutions in the U.S. and around the world. Fact-based information rooted in sound science is vitally important to overcoming the COVID-19 pandemic and Pfizer remains committed to transparency and helping alleviate the devastating burden of this disease. [link to www.pfizer.com (secure)] Scroll down to safety information and side effects that include myocarditis and pericarditis. Most of this work is conducted using computer simulations or mutations of the main protease–a non-infectious part of the virus. In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells. In addition, in vitro resistance selection experiments are undertaken in cells incubated with SARS-CoV-2 and nirmatrelvir in our secure Biosafety level 3 (BSL3) laboratory to assess whether the main protease can mutate to yield resistant strains of the virus. we told you this from the beginning.. smh Gold is the money of kings. Silver is the money of gentlemen. Barter is the money of peasants. Debt is the money of slaves |
GatorMclosky
User ID: 79159550 United States 01/28/2023 03:29 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 80091384 United States 01/28/2023 03:31 AM Report Abusive Post Report Copyright Violation | |
AnonG
User ID: 83504989 United States 01/28/2023 03:44 AM Report Abusive Post Report Copyright Violation | New York, N.Y., January 27, 2023 – Allegations have recently been made related to gain of function and directed evolution research at Pfizer and the company would like to set the record straight. Quoting: Happy in Nature In the ongoing development of the Pfizer-BioNTech COVID-19 vaccine, Pfizer has not conducted gain of function or directed evolution research. Working with collaborators, we have conducted research where the original SARS-CoV-2 virus has been used to express the spike protein from new variants of concern. This work is undertaken once a new variant of concern has been identified by public health authorities. This research provides a way for us to rapidly assess the ability of an existing vaccine to induce antibodies that neutralize a newly identified variant of concern. We then make this data available through peer reviewed scientific journals and use it as one of the steps to determine whether a vaccine update is required. In addition, to meet U.S. and global regulatory requirements for our oral treatment, PAXLOVID™, Pfizer undertakes in vitro work (e.g., in a laboratory culture dish) to identify potential resistance mutations to nirmatrelvir, one of PAXLOVID’s two components. With a naturally evolving virus, it is important to routinely assess the activity of an antiviral. Most of this work is conducted using computer simulations or mutations of the main protease–a non-infectious part of the virus. In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells. In addition, in vitro resistance selection experiments are undertaken in cells incubated with SARS-CoV-2 and nirmatrelvir in our secure Biosafety level 3 (BSL3) laboratory to assess whether the main protease can mutate to yield resistant strains of the virus. It is important to note that these studies are required by U.S. and global regulators for all antiviral products and are carried out by many companies and academic institutions in the U.S. and around the world. Fact-based information rooted in sound science is vitally important to overcoming the COVID-19 pandemic and Pfizer remains committed to transparency and helping alleviate the devastating burden of this disease. [link to www.pfizer.com (secure)] Scroll down to safety information and side effects that include myocarditis and pericarditis. Message to Pfizer: mess around and find out. . I know Satan rules this ROCK we call earth. A.I. - fück Ü2 May God ßless U. Peace ße with Ü too. |
Grove Street (Redux 3.0)
User ID: 85003305 United States 01/28/2023 04:00 AM Report Abusive Post Report Copyright Violation | ive heard from some GLP users gushing about how albert bourla and the pfizer crew are very very hunky men. i had to stop responding because it was getting kind of weird. i mean if you want to date albert bourla just go ahead and do it. no need to tell me ..TMI sorry to derail the thread OP...back to how Pfizer is the scourge of the earth. And this is why we can't have nice things. |
Anonymous Coward User ID: 82144571 United States 01/28/2023 04:01 AM Report Abusive Post Report Copyright Violation | AI Analysis: The article is written by a representative from Pfizer, which could lead to bias in the reporting as it is likely that they will be presenting their own company's research and products in a positive light. The article does not provide any evidence for the claims made, such as data from studies or trials that have been conducted on their products or research methods. Additionally, there is no mention of any potential risks associated with their products or research methods, which could be seen as a form of promotional content. Furthermore, there is no exploration of counterarguments or other points of view regarding their research methods or products, making it appear one-sided and potentially biased. Finally, there is no mention of any ethical considerations related to their research methods or products, which could be seen as an oversight on the part of the author. |
FastEddyTortuga
User ID: 85161179 United States 01/28/2023 04:03 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 84133212 Canada 01/28/2023 04:04 AM Report Abusive Post Report Copyright Violation | |
G3
User ID: 85139810 United States 01/28/2023 04:27 AM Report Abusive Post Report Copyright Violation | New York, N.Y., January 27, 2023 – Allegations have recently been made related to gain of function and directed evolution research at Pfizer and the company would like to set the record straight. Quoting: Happy in Nature In the ongoing development of the Pfizer-BioNTech COVID-19 vaccine, Pfizer has not conducted gain of function or directed evolution research. Working with collaborators, we have conducted research where the original SARS-CoV-2 virus has been used to express the spike protein from new variants of concern. This work is undertaken once a new variant of concern has been identified by public health authorities. This research provides a way for us to rapidly assess the ability of an existing vaccine to induce antibodies that neutralize a newly identified variant of concern. We then make this data available through peer reviewed scientific journals and use it as one of the steps to determine whether a vaccine update is required. In addition, to meet U.S. and global regulatory requirements for our oral treatment, PAXLOVID™, Pfizer undertakes in vitro work (e.g., in a laboratory culture dish) to identify potential resistance mutations to nirmatrelvir, one of PAXLOVID’s two components. With a naturally evolving virus, it is important to routinely assess the activity of an antiviral. Most of this work is conducted using computer simulations or mutations of the main protease–a non-infectious part of the virus. In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells. In addition, in vitro resistance selection experiments are undertaken in cells incubated with SARS-CoV-2 and nirmatrelvir in our secure Biosafety level 3 (BSL3) laboratory to assess whether the main protease can mutate to yield resistant strains of the virus. It is important to note that these studies are required by U.S. and global regulators for all antiviral products and are carried out by many companies and academic institutions in the U.S. and around the world. Fact-based information rooted in sound science is vitally important to overcoming the COVID-19 pandemic and Pfizer remains committed to transparency and helping alleviate the devastating burden of this disease. [link to www.pfizer.com (secure)] Scroll down to safety information and side effects that include myocarditis and pericarditis. Message to Pfizer: mess around and find out. Read the comments in this tweet. Lots of vaxxed who are angry as hell. https://twitter.com/_/status/1619221846389559297 |
Anonymous Coward User ID: 14552968 United States 01/28/2023 04:32 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 11112443 United States 01/28/2023 04:32 AM Report Abusive Post Report Copyright Violation | That's a strong denial. Quoting: Anonymous Coward 19145374 I don't know if they're lying but they definitely deny directed evolution research. The safety warnings are interesting. Let your "vaccination provider know if you have ever had myocarditis or pericarditis and You should not get COMIRNATY (COVID-19 Vaccine, mRNA), the Pfizer-BioNTech COVID-19 Vaccine, or the Pfizer-BioNTech COVID-19 Vaccine, Bivalent if you have had a severe allergic reaction after a previous dose of COMIRNATY or the Pfizer-BioNTech COVID-19 Vaccine or any ingredient in these vaccines. Hundreds of millions of people mandated, virtually ordered to get the injections never got these warnings! Based on the POS that Veritas just caught, who in their right mind would believe ANYTHING that these demonic cockroaches say? |
G3
User ID: 85139810 United States 01/28/2023 04:34 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 85141226 United States 01/28/2023 04:36 AM Report Abusive Post Report Copyright Violation | Looks like a confession to me. If they were "original" viruses how did they become "variants of concern" ? Quoting: Happy in Nature [link to twitter.com (secure)] And moreso, they didn't address the employee's statement that this was a "cash cow" for the company |
Anonymous Coward User ID: 85163992 Sweden 01/28/2023 05:43 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 82738869 United States 01/28/2023 05:46 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 83855242 01/28/2023 05:48 AM Report Abusive Post Report Copyright Violation | |
luisaywhitehat
User ID: 83974558 Germany 01/28/2023 05:50 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 78719253 United States 01/28/2023 05:51 AM Report Abusive Post Report Copyright Violation | |
Aruna888
User ID: 84985175 United States 01/28/2023 05:51 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 82502773 New Zealand 01/28/2023 06:01 AM Report Abusive Post Report Copyright Violation | That's a strong denial. Quoting: Anonymous Coward 19145374 I don't know if they're lying but they definitely deny directed evolution research. The safety warnings are interesting. Let your "vaccination provider know if you have ever had myocarditis or pericarditis and You should not get COMIRNATY (COVID-19 Vaccine, mRNA), the Pfizer-BioNTech COVID-19 Vaccine, or the Pfizer-BioNTech COVID-19 Vaccine, Bivalent if you have had a severe allergic reaction after a previous dose of COMIRNATY or the Pfizer-BioNTech COVID-19 Vaccine or any ingredient in these vaccines. Hundreds of millions of people mandated, virtually ordered to get the injections never got these warnings! I had to sign after reading all these warnings when I got Comirnaty over a year ago. You just don’t know because you didn’t get vaccinated. Everyone got the warnings |
Anonymous Coward User ID: 82502773 New Zealand 01/28/2023 06:04 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 78719253 United States 01/28/2023 06:04 AM Report Abusive Post Report Copyright Violation | That's a strong denial. Quoting: Anonymous Coward 19145374 I don't know if they're lying but they definitely deny directed evolution research. The safety warnings are interesting. Let your "vaccination provider know if you have ever had myocarditis or pericarditis and You should not get COMIRNATY (COVID-19 Vaccine, mRNA), the Pfizer-BioNTech COVID-19 Vaccine, or the Pfizer-BioNTech COVID-19 Vaccine, Bivalent if you have had a severe allergic reaction after a previous dose of COMIRNATY or the Pfizer-BioNTech COVID-19 Vaccine or any ingredient in these vaccines. Hundreds of millions of people mandated, virtually ordered to get the injections never got these warnings! I had to sign after reading all these warnings when I got Comirnaty over a year ago. You just don’t know because you didn’t get vaccinated. Everyone got the warnings |
Festus J. Hoggbottom, III
User ID: 84062326 United States 01/28/2023 06:05 AM Report Abusive Post Report Copyright Violation | “In a limited number of cases when a full virus does not contain any known gain of function mutations, such virus may be engineered to enable the assessment of antiviral activity in cells” Quoting: Happy in Nature - this implies they have worked on viruses that have had GoF. Is that new information?? [link to twitter.com (secure)] No information. No questions. Just obey. I did it. I did it on purpose. And I'll do it again. |
Anonymous Coward User ID: 84964991 United States 01/28/2023 06:20 AM Report Abusive Post Report Copyright Violation | I watched tuckers relevant clips of the project veritas videos and the Pfizer guy the whole time used words like “considering” and such which means they aren’t doing it. At least they are spooked now and won’t go near anything like gain of function. Quoting: Gargantuan Tarantula YOU AREN'T DOING THEM ANY FAVORS WITH THIS CHILDLIKE LEVEL OF EYE WASH. THEY EMPLOYED THE VERY GAY MAN. HE IS EITHER TELLING THE TRUTH AND GOT CAUGHT, OR HE IS- LIKE MOST HOMOSEXUALS- A PATHOLOGICAL LIAR. EITHER WAY THAT'S WHO THIS COMPANY IS EMPLOYING IN THEIR TOP RANKS. WHICH OF THOSE OPTIONS INSPIRES TRUST? IN A JUST WORLD THE ENTIRE COMPANY WOULD BE TAKEN OFF THE MARKET UNTIL AN INVESTIGATION COULD GET TO THE BOTTOM OF THE PROBLEM. WE DON'T LIVE IN A JUST WORLD OF COURSE, BUT THAT WOULD BE THE PRUDENT THING TO DO AS IT RELATES TO PUBLIC HEALTH. "AT LEAST THEY ARE SPOOKED NOW AND WON'T GO NEAR ANYTHING LIKE GAIN OF FUNCTION" SOUNDS RIDICULOUS TO ME AND IF YOU ACTUALLY BEIEVE THAT YOU NEED SOMEONE ELSE MAKING DECISIONS FOR YOU BECAUSE YOU CLEARLY ARE MISSING ANY KIND OF COMMON SENSE AND JUDGEMENT. |
Anonymous Coward User ID: 82502773 New Zealand 01/28/2023 06:24 AM Report Abusive Post Report Copyright Violation | I watched tuckers relevant clips of the project veritas videos and the Pfizer guy the whole time used words like “considering” and such which means they aren’t doing it. At least they are spooked now and won’t go near anything like gain of function. Quoting: Gargantuan Tarantula YOU AREN'T DOING THEM ANY FAVORS WITH THIS CHILDLIKE LEVEL OF EYE WASH. THEY EMPLOYED THE VERY GAY MAN. HE IS EITHER TELLING THE TRUTH AND GOT CAUGHT, OR HE IS- LIKE MOST HOMOSEXUALS- A PATHOLOGICAL LIAR. EITHER WAY THAT'S WHO THIS COMPANY IS EMPLOYING IN THEIR TOP RANKS. WHICH OF THOSE OPTIONS INSPIRES TRUST? IN A JUST WORLD THE ENTIRE COMPANY WOULD BE TAKEN OFF THE MARKET UNTIL AN INVESTIGATION COULD GET TO THE BOTTOM OF THE PROBLEM. WE DON'T LIVE IN A JUST WORLD OF COURSE, BUT THAT WOULD BE THE PRUDENT THING TO DO AS IT RELATES TO PUBLIC HEALTH. "AT LEAST THEY ARE SPOOKED NOW AND WON'T GO NEAR ANYTHING LIKE GAIN OF FUNCTION" SOUNDS RIDICULOUS TO ME AND IF YOU ACTUALLY BEIEVE THAT YOU NEED SOMEONE ELSE MAKING DECISIONS FOR YOU BECAUSE YOU CLEARLY ARE MISSING ANY KIND OF COMMON SENSE AND JUDGEMENT. I don’t care, I’m posting my opinion. I said he used caveats the whole time so veritas running with “they are doing directed evolution” when the guy was saying “we are considering that” or “looking into it” just makes everyone look stupid except the Pfizer guy who didn’t really confirm anything at all. |
Anonymous Coward User ID: 78719253 United States 01/28/2023 06:27 AM Report Abusive Post Report Copyright Violation | I watched tuckers relevant clips of the project veritas videos and the Pfizer guy the whole time used words like “considering” and such which means they aren’t doing it. At least they are spooked now and won’t go near anything like gain of function. Quoting: Gargantuan Tarantula YOU AREN'T DOING THEM ANY FAVORS WITH THIS CHILDLIKE LEVEL OF EYE WASH. THEY EMPLOYED THE VERY GAY MAN. HE IS EITHER TELLING THE TRUTH AND GOT CAUGHT, OR HE IS- LIKE MOST HOMOSEXUALS- A PATHOLOGICAL LIAR. EITHER WAY THAT'S WHO THIS COMPANY IS EMPLOYING IN THEIR TOP RANKS. WHICH OF THOSE OPTIONS INSPIRES TRUST? IN A JUST WORLD THE ENTIRE COMPANY WOULD BE TAKEN OFF THE MARKET UNTIL AN INVESTIGATION COULD GET TO THE BOTTOM OF THE PROBLEM. WE DON'T LIVE IN A JUST WORLD OF COURSE, BUT THAT WOULD BE THE PRUDENT THING TO DO AS IT RELATES TO PUBLIC HEALTH. "AT LEAST THEY ARE SPOOKED NOW AND WON'T GO NEAR ANYTHING LIKE GAIN OF FUNCTION" SOUNDS RIDICULOUS TO ME AND IF YOU ACTUALLY BEIEVE THAT YOU NEED SOMEONE ELSE MAKING DECISIONS FOR YOU BECAUSE YOU CLEARLY ARE MISSING ANY KIND OF COMMON SENSE AND JUDGEMENT. I don’t care, I’m posting my opinion. I said he used caveats the whole time so veritas running with “they are doing directed evolution” when the guy was saying “we are considering that” or “looking into it” just makes everyone look stupid except the Pfizer guy who didn’t really confirm anything at all. He also said he's literally a liar |
Dame
User ID: 81062980 United States 01/28/2023 06:36 AM Report Abusive Post Report Copyright Violation | |