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Message Subject CoronaVirus is a VERY Toxic Super Virus -- Insight from CHINA
Poster Handle Krispy71
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Have you guys seen this discussion on the Sars vaccine.....

Thread: If I were you I probably wouldn't ignore this.
 Quoting: Anonymous Coward 74652197


Yes very intersting !


I would like constructive (only) feed back on my theory please.

Okay guys, I've tried to restrain myself on this whole coronavirus thing and I think I've done pretty well, lol. I have, however, been doing a ton of research. Probably more than you'd care to read about. So I'm going to be as brief as possible.

First, let me say that there is no need for panic. most US citizens are not at risk for getting the pathological changes in their lungs that are causing deaths in China.

As a matter of fact, as of yesterday, there were 1,770 deaths from the Coronavirus. All of them, with the exception of FOUR occurred in China. I have done research on the four people that have died and found that ALL OF THEM had connections to Asia.

Why is this important?

Keep in mind that as of today, there are 77,000 people diagnosed with the Coronavirus. 26 different countries have reported cases of the virus. Yet only 4 deaths outside of China?

It's been 7 weeks since China admitted they had a pandemic on their hands, surely we'd be seeing a higher death rate outside of China by now, especially because many think the Coronavirus started at least 1 month prior to China's official announcement.

So here's why I am almost positive based on what we've seen so far, that US citizens have nothing to worry about.

Back when the SARs virus was going around, researchers created a vaccine for it. Unfortunately, they found this (I will not change the wording, I'm leaving it exactly as it was written).

“The researchers created vaccines based on SARS-CoV S and SARS-CoV N by taking the genes coding for those proteins and inserting them into another type of virus particle that acted as a delivery vehicle. They injected mice with these vaccines and then tested whether the mice generated an immune response against the specific SARS proteins, which they did. The next step was to work out whether mice injected with the vaccines would be protected against later infection with SARS-CoV. The researchers found that mice injected with vaccine based on SARS-CoV S were protected against later infection with a standard SARS-CoV strain, both in the short term (eight weeks after vaccination) and the long term (54 weeks after vaccination). However, the vaccine based on SARS-CoV N did not seem to result in protection, and, worryingly, caused pathological changes in the lungs of mice following virus challenge.”

[link to www.ncbi.nlm.nih.gov (secure)]


Now, fast forward to the Coronavirus....Here is the genome sequencing for the Coronavirus (known as 2019-N CoV)...

[link to www.mdpi.com (secure)]

Do I expect you to read and understand all of this? NO!
What I want you to see is this paragraph:

"2019-nCoV antibodies against the N protein would likely recognize and bind the SARS-CoV N protein as well. N antibodies do not provide immunity to 2019-nCoV infection, but the cross reactivity with SARS-CoV N protein would allow a serum based assay to determine exposure to the novel CoV in asymptomatic cases."

So what does all of this mean?

In layman's terms, a vaccine was made for the SARS virus. Researchers then found that when they reinfected mice with SARS again 54 weeks after vaccination, they saw pathological changes in the lungs of the vaccinated mice.

This same exact protein is is the 2019 -nCoV virus. So, what do you think is going to happen to the people who already had the SARs vaccine and now get re-infected? You're seeing it! They get pnuemonia (and worse) and die! And WHERE do you think the people who got SARs vaccines live? In Asian countries, most in CHINA where SARs originated!

Can you get the coronavirus? YES
You can get any virus.
Will you die from it? Probably not, unless you are already very compromised OR have had the SARs vaccine.

Of course, the powers to be will NEVER admit that a vaccine is actually causing these deaths, but look at the entire picture, so far, my theory is proving to be true. Time will tell.
 Quoting: Wildthing3




So only the N-vaccine gave pathological changes in the lungs of the vaccinated mice ...
* (I added underlines bold and color in the copied post)

i looked up the document [link to www.ncbi.nlm.nih.gov (secure)]

Worrisome also about the S-version = The researchers found that the vaccine based on SARS-CoV S protected against infection by the test virus when mice were vaccinated young, but it failed to efficiently protect when administered to older mice.[
The findings confirm others suggesting that vaccines based on the SARS-CoV S protein are more effective than those based on SARS-CoV N. They also suggest that the former can provide long-term protection in animals vaccinated young against closely related viruses. However, protection against more distantly related viruses remains a challenge, especially when vaccinating older animals

... not only did N vaccination fail to control SARS-CoV replication within the lungs, but N vaccination also resulted in an enhanced immunopathology in the lungs of the senescent animals upon viral challenge.

... concerns that vaccination with N alone will not only fail to effectively protect against SARS-CoV replication, but may result in vaccine-enhanced pulmonary disease [57]. N-induced pathology has not been previously reported, probably because most studies examined young mice at 2–3 d post-infection, prior to the infiltration of inflammatory cells into the lung. VRP-N–induced pathology was clearly evident by day 4 and persisted for 1–2 wk following wild-type virus challenge, suggesting the potential for serious complications in lung physiology and function. This finding has particular significance for SARS-N and inactivated SARS-CoV vaccines currently under development that also induce anti-N antibody and T cell responses [12,19,21,26,58–61], because they may lead to adverse effects. Therefore, caution is merited with respect to the inclusion of SARS-CoV N protein in any vaccine formulation. The passive transfer of anti-N antibody did not contribute to inflammation and leads us to hypothesize that it is the activity of SARS-N–specific T cells in the absence of effective neutralizing anti–SARS-CoV antibody that mediates the adverse response. It is interesting that a Th2–skewed cytokine profile is a hallmark of the RSV vaccine-enhanced disease, which raises the possibility that the N-specific immune response is skewed in a similar manner.

... aging decreases B and T cell immunity and innate immune function in humans ...

... Our research provides a model for future experiments designed to characterize the components and inducers of the VRP-N–enhanced pulmonary inflammation, and suggests that vaccine regimens that contain N protein should be used with caution in human populations until further testing.


The N stands for nucleocapsid = a unit of viral structure, consisting of a capsid with the enclosed nucleic acid; it is generally inside the cytoplasm.
The nucleic acid of a virus together with the protein coat that encloses it.

The nucleocapsid Protein (N-protein) is the most abundant protein in coronavirus. The N-protein is a highly immunogenic phosphoprotein, and it is normally very conserved. The N protein of coronavirus is often used as a marker in diagnostic assays. N protein binds to viral RNA.

During the virus life cycle, multiple copies of the nucleocapsid phosphoprotein (N) interact intimately with genomic and subgenomic RNA molecules and together with M, the most abundant envelope protein, participate in genome condensation and packaging. The N and M proteins interact via their C termini, leading to specific genome encapsidation in the budding viral particle. In addition to its structural role, the nucleocapsid protein is also implicated in other processes during infection including mRNA transcription, replication, and host cell modulation.


burnit braincrash ...lol...


The thing about T-cells stood out

It made me think back about this snip from an other quote in my earlier post :
"To stop heart activated T-cell death the Japanese are trying treatment with HIV antivirals.
Chronic inflammation after a heart attack can promote heart failure and death. University of Alabama at Birmingham researchers have now shown that activated T-cells -- part of the immune system's inflammatory response -- are both necessary and sufficient to produce such heart failure.
"

As is seen in the corona-victims ...

This N-protein has 2 variants :
1- HIV-1 nucleocapsid protein (NC) functions in the early and late phases of virus replication. One of the salient feature of the nucleocapsid central globular domain is an hydrophobic plateau which appears to orchestrate the nucleocapsid functions, such as chaperoning the conversion of the genomic RNA into viral DNA by RT during the early phase, and driving the selection and dimerization of the genomic RNA at the initial stage of viral particle assembly.
2- IBV nucleocapsid is a prototype coronavirus nucleocapsid

read more here: [link to www.sinobiological.com (secure)]


Remember my post about HIV-1 in the coronavirus, mentioning this research [link to www.biorxiv.org (secure)] :

We found 4 insertions in the spike glycoprotein (S) which are unique to the 2019-nCoV and are not present in other coronaviruses. Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV-1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute the receptor binding site. The finding of 4 unique inserts in the 2019-nCoV, all of which have identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature. ... However, it is unlikely that all 4 inserts in the 2019-nCoV spike glycoprotein fortuitously match with 2 key structural proteins of an unrelated virus (HIV-1).. ...
Since the 2019-nCoV inserts mapped to variable regions of HIV-1, they were not ubiquitous in HIV-1 gp120, but were limited to selected sequences of HIV-1 [refer S.File1] primarily from Asia and Africa.
As none of these 4 inserts are present in any other coronavirus, the genomic region encoding these inserts represent ideal candidates for designing primers that can distinguish 2019-nCoV from other coronaviruses.
The novel inserts are part of the receptor binding site of 2019-nCoV



So that is the reason why the virus responds to treatment by HIV medications. (as shown and reported with victims in Japan)

So is the N in "2019-nCoV " then maybe NOT the N for NOVEL ... but N for nucleocapsid !!!!????!!


xxxK
 
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