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Nafamostat and Ivermectin -The Perfect Drug Combo Cure?

 
glug glug
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04/17/2020 08:11 AM
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Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
Nafamostat is the drug currently being used for pancreatitis and some other deseases but its showing great promise as a Covid 19 treatment because it blocks the virus from even attaching to the ACE2 lung cell. It does this because its a protease inhibitor. Yesterday it occurred to me that if Nafamostat was interrupted the virus would start attacking cells again. In other words the desease would return. I'm not 100% sure because I'm not a scientist but you can't keep taking drugs forever. Who wants to be on Nafamostat all the time? Not me, so I thought what about taking another drug to finish the job. Ivermectim has been shown to destroy the RNA in the virus completely. That's right completely. Ivermectin is also a fda approved drug just like Nafamostat but its not in use against Covod 19 yet. Its a good candidate though. It kills Covid dead. Knocks it out cold. Ivermectin would be great as an adjunct medication to be used along with Nafamostat (if their comparable). Testing is required of course but remember these drugs have already been approved for other ailments.

Conclusion

Nafamostat will block the virus.

Ivermectin will kill it.

The ultimate double whammy.

And then it can't return!



I am not a Doctor. Please consult a Doctor before using any drugs mentioned here in this post, even if they are FDA approved.
Anonymous Coward (OP)
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04/17/2020 08:12 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
[link to www.eurekalert.org (secure)]
Anonymous Coward (OP)
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04/17/2020 08:14 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
[link to www.eurekalert.org (secure)]
Anonymous Coward (OP)
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04/17/2020 08:15 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
[link to www.sciencedirect.com (secure)]
Anonymous Coward (OP)
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04/17/2020 08:18 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
[link to www.medicinenet.com (secure)]
Anonymous Coward (OP)
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04/17/2020 08:40 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
hiding
Anonymous Coward (OP)
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04/17/2020 08:48 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
Dr Kylie Wagstaff from Monash Biomedicine Discovery Institute’s commented, “We found that even a single dose could essentially remove all viral RNA by 48 hours and that even at 24 hours there was a really significant reduction in it.”
Anonymous Coward (OP)
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04/17/2020 09:01 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
bump
Anonymous Coward
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04/17/2020 11:37 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
Any thoughts on this?
Anonymous Coward
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04/17/2020 11:38 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
Seems logical

Spock
glug glug
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04/17/2020 02:35 PM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
I sent an email to Health Sciences North about this and still waiting to hear back. Apparently they don't answer their email?

question
Anonymous Coward
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04/17/2020 02:52 PM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
I've seen more progress made on GLP than by big pharma. Big Pharma obviously sees this some ultimate cash cow and is going to try and crush everything except its money making drug of choice.

But good thinking.
Anonymous Coward
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United Kingdom
04/17/2020 02:53 PM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
cattle drench is primarily ivermectin
Anonymous Coward
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04/17/2020 02:54 PM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
every year i used to get covered in the stuff as the bottle strapped to my back would leak and run down my back.

no side effects yet.
Anonymous Coward
User ID: 77684474
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04/17/2020 03:42 PM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
Nafamostat is the drug currently being used for pancreatitis and some other deseases but its showing great promise as a Covid 19 treatment because it blocks the virus from even attaching to the ACE2 lung cell. It does this because its a protease inhibitor. Yesterday it occurred to me that if Nafamostat was interrupted the virus would start attacking cells again. In other words the desease would return. I'm not 100% sure because I'm not a scientist but you can't keep taking drugs forever. Who wants to be on Nafamostat all the time? Not me, so I thought what about taking another drug to finish the job. Ivermectim has been shown to destroy the RNA in the virus completely. That's right completely. Ivermectin is also a fda approved drug just like Nafamostat but its not in use against Covod 19 yet. Its a good candidate though. It kills Covid dead. Knocks it out cold. Ivermectin would be great as an adjunct medication to be used along with Nafamostat (if their comparable). Testing is required of course but remember these drugs have already been approved for other ailments.

Conclusion

Nafamostat will block the virus.

Ivermectin will kill it.

The ultimate double whammy.

And then it can't return!



I am not a Doctor. Please consult a Doctor before using any drugs mentioned here in this post, even if they are FDA approved.
 Quoting: glug glug 43864422


Great post. I've been thinking the same thing: if they both work, this could be a K.O. It's been nothing but crickets on the ivermectin since the in vitro studies were reported awhile ago. I did see some positive anecdotal results reported a couple weeks ago regarding a small human application of it, but I can't find the story again. Hopefully it's as good in the body as in the tube.

I do wonder about the ability of these drugs to cross the blood-brain (or blood-brian) barrier. Wouldn't that be essential? Maybe someone here would know how that comes into play.
Anonymous Coward
User ID: 50668786
United Kingdom
04/17/2020 03:45 PM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
Nafamostat is the drug currently being used for pancreatitis and some other deseases but its showing great promise as a Covid 19 treatment because it blocks the virus from even attaching to the ACE2 lung cell. It does this because its a protease inhibitor. Yesterday it occurred to me that if Nafamostat was interrupted the virus would start attacking cells again. In other words the desease would return. I'm not 100% sure because I'm not a scientist but you can't keep taking drugs forever. Who wants to be on Nafamostat all the time? Not me, so I thought what about taking another drug to finish the job. Ivermectim has been shown to destroy the RNA in the virus completely. That's right completely. Ivermectin is also a fda approved drug just like Nafamostat but its not in use against Covod 19 yet. Its a good candidate though. It kills Covid dead. Knocks it out cold. Ivermectin would be great as an adjunct medication to be used along with Nafamostat (if their comparable). Testing is required of course but remember these drugs have already been approved for other ailments.

Conclusion

Nafamostat will block the virus.

Ivermectin will kill it.

The ultimate double whammy.

And then it can't return!



I am not a Doctor. Please consult a Doctor before using any drugs mentioned here in this post, even if they are FDA approved.
 Quoting: glug glug 43864422


Great post. I've been thinking the same thing: if they both work, this could be a K.O. It's been nothing but crickets on the ivermectin since the in vitro studies were reported awhile ago. I did see some positive anecdotal results reported a couple weeks ago regarding a small human application of it, but I can't find the story again. Hopefully it's as good in the body as in the tube.

I do wonder about the ability of these drugs to cross the blood-brain (or blood-brian) barrier. Wouldn't that be essential? Maybe someone here would know how that comes into play.
 Quoting: Anonymous Coward 77684474


i know a family of 5 farmers, all live together. one of them came down sick with corona symptoms. they all got tested. 3 came back positive for corona. the other 2 came back negative. they repeated the test for the other 2, still negative.

they were baffled how they didn't have coronavirus at all, not even an old corona infection caused a positive result.

they thought hard about why they were negative when the rest of the family had been positive and they had been exposed just the same.

they realized then when ivermectin was talked about as a cure that a couple of days prior only the two who tested negative had been drenching the cows primarily with ivermectin .

so take it for what you will.
Anonymous Coward
User ID: 41281812
Canada
04/17/2020 05:54 PM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
Nafamostat is the drug currently being used for pancreatitis and some other deseases but its showing great promise as a Covid 19 treatment because it blocks the virus from even attaching to the ACE2 lung cell. It does this because its a protease inhibitor. Yesterday it occurred to me that if Nafamostat was interrupted the virus would start attacking cells again. In other words the desease would return. I'm not 100% sure because I'm not a scientist but you can't keep taking drugs forever. Who wants to be on Nafamostat all the time? Not me, so I thought what about taking another drug to finish the job. Ivermectim has been shown to destroy the RNA in the virus completely. That's right completely. Ivermectin is also a fda approved drug just like Nafamostat but its not in use against Covod 19 yet. Its a good candidate though. It kills Covid dead. Knocks it out cold. Ivermectin would be great as an adjunct medication to be used along with Nafamostat (if their comparable). Testing is required of course but remember these drugs have already been approved for other ailments.

Conclusion

Nafamostat will block the virus.

Ivermectin will kill it.

The ultimate double whammy.

And then it can't return!



I am not a Doctor. Please consult a Doctor before using any drugs mentioned here in this post, even if they are FDA approved.
 Quoting: glug glug 43864422


Great post. I've been thinking the same thing: if they both work, this could be a K.O. It's been nothing but crickets on the ivermectin since the in vitro studies were reported awhile ago. I did see some positive anecdotal results reported a couple weeks ago regarding a small human application of it, but I can't find the story again. Hopefully it's as good in the body as in the tube.

I do wonder about the ability of these drugs to cross the blood-brain (or blood-brian) barrier. Wouldn't that be essential? Maybe someone here would know how that comes into play.
 Quoting: Anonymous Coward 77684474


i know a family of 5 farmers, all live together. one of them came down sick with corona symptoms. they all got tested. 3 came back positive for corona. the other 2 came back negative. they repeated the test for the other 2, still negative.

they were baffled how they didn't have coronavirus at all, not even an old corona infection caused a positive result.

they thought hard about why they were negative when the rest of the family had been positive and they had been exposed just the same.

they realized then when ivermectin was talked about as a cure that a couple of days prior only the two who tested negative had been drenching the cows primarily with ivermectin .

so take it for what you will.
 Quoting: Anonymous Coward 50668786


Thats very interesting! Thanks for posting that!
Anonymous Coward
User ID: 39270327
Canada
04/24/2020 09:07 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
bump
Anonymous Coward
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04/24/2020 09:17 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
"Usually prescribed for pinworm and nematode infections, and sometimes head lice, ivermectin (Stromectol) was shown to reduce viral colonies of COVID-19 by 5,000 times within 48 hours of a single treatment in a cell culture infected in a laboratory. This test was not performed on humans."


[link to www.medicinenet.com (secure)]
Anonymous Coward
User ID: 75758325
United States
04/24/2020 09:18 AM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
I've seen more progress made on GLP than by big pharma. Big Pharma obviously sees this some ultimate cash cow and is going to try and crush everything except its money making drug of choice.

But good thinking.
 Quoting: Anonymous Coward 77967240


shows you


a community looking out for itself does a fantastic job compared to....another type of community
Pilgrim001

User ID: 78018011
United States
05/18/2020 08:06 PM

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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
Any thoughts on this?
 Quoting: Anonymous Coward 43226228


As it is turning out, Gates19 is becoming very easy to cure.

Gates is probably crying himself to sleep at the thought of not giving 7 Billion people his vaccine/id chip.
I don't have the time or the crayons to explain this to you.



Slake Blake
glug glug
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12/31/2022 09:12 PM
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Re: Nafamostat and Ivermectin -The Perfect Drug Combo Cure?
Just found one of my old threads.





GLP