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Coronavirus Intel Clearinghouse

 
THE AMERICAN INQUISITOR

User ID: 78136663
United States
02/10/2020 10:44 AM

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Re: Coronavirus Intel Clearinghouse
001 hasn't commented in a couple of days, it seems. Anyone have any updates on him?
 Quoting: Anonymous Coward 78322848


She ran out of socks
 Quoting: Anonymous Coward 77621519


LOL..

sdfghjkl

Last Edited by THE AMERICAN INQUISITOR on 02/10/2020 10:44 AM
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SkyTraveler

User ID: 77755160
United States
02/10/2020 10:45 AM

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Re: Coronavirus Intel Clearinghouse
001...

Thank you for continuing to share.

You’ve been doing your thing for some time and considered an expert.

Have you ever studied a virus like this? What makes it most challenging?

Are you able to see all aspects of the virus? Is there anything spooky? Like it’s moving in ways that are unnatural?

Do you think there is a possibility of some type of artificial intelligence that’s been embedded into this virus?

It feels intelligent. It feels predatory.

Can you share from your scientific perspective but also from your gut? Which I know is probably counterintuitive for you but I feel both matter.
 Quoting: SkyTraveler


Good morning 001,

I’m not sure if you saw or were able to respond to my questions. Or maybe you ignored them. ;)

I appreciate your viewpoint on it’s unlikely to be a bio weapon. It’s not my focus right now...but...I can’t help feeling there’s something not right here.

Is there any nanotechnology in his thing?

Once someone recovers what changes are being observed? After effects? DNA changes?

Your presence on this site shows me you can think out of the box and understand the prison like systems that confine solution oriented intelligent creativity.

That CCP warning feels... gauntlet dropping. So my gut is ringing. I’m not a scientist but I’m unique in being able to find...things. It’s a balance between thinking and intuition. Something is not right and you all working in separate project boxes I feel strongly is going to delay solutions.

Can you suggest gathering a team from various expertise to come together and strategize on this? You can still have teams working on traditional approaches too but again I feel we need a team that’s not confined to hard rules.

Thank you. Take Care.
 Quoting: SkyTraveler


I was eating an orange this morning and found a tiny orange hidden in it. Maybe there is something hiding in the hiv proteins? Or somewhere else?

I’m out for a bit. Thank you
 Quoting: SkyTraveler


Good morning 001,

I hope your work is progressing well.

I know you posted here to share and without authorization but I’m wondering if that has changed. Or could it change?

Given what’s unfolding it’s in everyone’s best interest to prepare some for the coming panic. Even the ones who are shills will psychologically be better prepared. Yes?

No one is ready for this. And things you shared are now visible in the media (i.e. drs with CV Unknowingly treating patients). So, this could be a good place to prep minds and plant the seeds of courage.

For me, I’ve prepared for shelter in place but I’m also prepared to treat others and exit earth.

If you guys don’t figure out a way to stop this thing I don’t see any other options. I don’t have and can’t afford a bio suit for myself or everyone else in my family.

And I’ve observed that when serious danger is present most humans just go into denial. It’s like their natural instincts are wonky now.

So, any progress?

Thank you

p.s. I hate surprises good or bad. Prep me please.
SkyTraveler
Anonymous Coward
User ID: 52353986
United States
02/10/2020 10:54 AM
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Re: Coronavirus Intel Clearinghouse
There was a post here from last week, a researcher described some over the counter meds to fight the cytokine storm. One was tagamet I belive.

Could anyone PLEASE post the link to it? I cannot find it again.

Thank you!
 Quoting: Anonymous Coward 52353986

Here you go

I think this is great info too that people should see, glad I added to favorites.


Thread: Email I just sent to my estranged wife regarding Coronavirus. THIS COULD SAVE LIVES...
 Quoting: flavapor



THANK YOU!!! :)
Anonymous Coward
User ID: 78420351
United States
02/10/2020 10:57 AM
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Re: Coronavirus Intel Clearinghouse
001 hasn't commented in a couple of days, it seems. Anyone have any updates on him?
 Quoting: Anonymous Coward 78322848


My bet is the .gov found the "leaker".
-001 mentioned some things I was concerned could compromise him.
The .gov is clamping down hard on all Ncov info and rumor is all social media will be forced to delete all Ncov related info/posts very soon.
As -001 said, the gov knows what is coming and are doing everything they can to prevent panic as long as possible.
Locking down info is crucial in that aspect.
BodilessModerator
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02/10/2020 10:59 AM

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Re: Coronavirus Intel Clearinghouse
OP, I’m not a medical professional. However, based on my “layman” research, it’s clear that this virus is similar to SARS in many respects.

I’m finding conflicting information in the matter of ACE-2 that I’m hoping you may clarify.

I’m finding some articles advocating for increasing ACE2 levels to protect against lowered values caused by infection, yet other articles seem to indicate that inhibition of ACE-2 helps to prevent infection.

Can you please offer your insights and recommendations?

Thanks in advance. I’m tracking this thread several times a day for updates.
.
 Quoting: Anonymous Coward 75214035


Hello 011, from another thread:

The wuhan virus is identical to the ACE2 key-- and it fits into the keyhole.

So-- flooding the body with ACE2 would be a means of sopping up the virus-- NOT inhibiting ACE2.


What's your take on that.. some suggested ACE2 inhibitors, but this person thinks it could make matters worse.
 Quoting: Anonymous Coward 78455686


^^these!!
Would taking an ACE inhibitor for already high blood pressure be beneficial or problematic?
 Quoting: Anonymous Coward 75833332


The ACE2 receptor is merely the route of ingress of NCoV INTO the cell—it does nothing else. Overdosing on ACE2 inhibitor meds would have very serious cardiovascular/vasopressin results. I would recommend NOT doing this. Same with ARBs, the receptor site(ACE2) is complex. Wish it were

Once inside the cell it disables the Tregulator cells which is what is used to inhibit the positive feedback loop cytokines storm

Vit D plays a part in the formulation/differentiation of the myloproliferative cell into a Tregulator cell
Anonymous Coward
User ID: 66662033
United States
02/10/2020 11:05 AM
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Re: Coronavirus Intel Clearinghouse
Coronavirus and possible treatment options by Dr. Paul Cottrell

Anonymous Coward
User ID: 78451566
United States
02/10/2020 11:08 AM
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Re: Coronavirus Intel Clearinghouse
001...

Thank you for continuing to share.

You’ve been doing your thing for some time and considered an expert.

Have you ever studied a virus like this? What makes it most challenging?

Are you able to see all aspects of the virus? Is there anything spooky? Like it’s moving in ways that are unnatural?

Do you think there is a possibility of some type of artificial intelligence that’s been embedded into this virus?

It feels intelligent. It feels predatory.

Can you share from your scientific perspective but also from your gut? Which I know is probably counterintuitive for you but I feel both matter.
 Quoting: SkyTraveler


Good morning 001,

I’m not sure if you saw or were able to respond to my questions. Or maybe you ignored them. ;)

I appreciate your viewpoint on it’s unlikely to be a bio weapon. It’s not my focus right now...but...I can’t help feeling there’s something not right here.

Is there any nanotechnology in his thing?

Once someone recovers what changes are being observed? After effects? DNA changes?

Your presence on this site shows me you can think out of the box and understand the prison like systems that confine solution oriented intelligent creativity.

That CCP warning feels... gauntlet dropping. So my gut is ringing. I’m not a scientist but I’m unique in being able to find...things. It’s a balance between thinking and intuition. Something is not right and you all working in separate project boxes I feel strongly is going to delay solutions.

Can you suggest gathering a team from various expertise to come together and strategize on this? You can still have teams working on traditional approaches too but again I feel we need a team that’s not confined to hard rules.

Thank you. Take Care.
 Quoting: SkyTraveler


I was eating an orange this morning and found a tiny orange hidden in it. Maybe there is something hiding in the hiv proteins? Or somewhere else?

I’m out for a bit. Thank you
 Quoting: SkyTraveler


Good morning 001,

I hope your work is progressing well.

I know you posted here to share and without authorization but I’m wondering if that has changed. Or could it change?

Given what’s unfolding it’s in everyone’s best interest to prepare some for the coming panic. Even the ones who are shills will psychologically be better prepared. Yes?

No one is ready for this. And things you shared are now visible in the media (i.e. drs with CV Unknowingly treating patients). So, this could be a good place to prep minds and plant the seeds of courage.

For me, I’ve prepared for shelter in place but I’m also prepared to treat others and exit earth.

If you guys don’t figure out a way to stop this thing I don’t see any other options. I don’t have and can’t afford a bio suit for myself or everyone else in my family.

And I’ve observed that when serious danger is present most humans just go into denial. It’s like their natural instincts are wonky now.

So, any progress?

Thank you

p.s. I hate surprises good or bad. Prep me please.
 Quoting: SkyTraveler





Kindness and only kindness can save the world now.

we're doomed, in other words.
Anonymous Coward
User ID: 72321131
United States
02/10/2020 11:40 AM
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Re: Coronavirus Intel Clearinghouse
OP, I’m not a medical professional. However, based on my “layman” research, it’s clear that this virus is similar to SARS in many respects.

I’m finding conflicting information in the matter of ACE-2 that I’m hoping you may clarify.

I’m finding some articles advocating for increasing ACE2 levels to protect against lowered values caused by infection, yet other articles seem to indicate that inhibition of ACE-2 helps to prevent infection.

Can you please offer your insights and recommendations?

Thanks in advance. I’m tracking this thread several times a day for updates.
.
 Quoting: Anonymous Coward 75214035


Hello 011, from another thread:

The wuhan virus is identical to the ACE2 key-- and it fits into the keyhole.

So-- flooding the body with ACE2 would be a means of sopping up the virus-- NOT inhibiting ACE2.


What's your take on that.. some suggested ACE2 inhibitors, but this person thinks it could make matters worse.
 Quoting: Anonymous Coward 78455686


^^these!!
Would taking an ACE inhibitor for already high blood pressure be beneficial or problematic?
 Quoting: Anonymous Coward 75833332


The ACE2 receptor is merely the route of ingress of NCoV INTO the cell—it does nothing else. Overdosing on ACE2 inhibitor meds would have very serious cardiovascular/vasopressin results. I would recommend NOT doing this. Same with ARBs, the receptor site(ACE2) is complex. Wish it were

Once inside the cell it disables the Tregulator cells which is what is used to inhibit the positive feedback loop cytokines storm

Vit D plays a part in the formulation/differentiation of the myloproliferative cell into a Tregulator cell
 Quoting: Bodiless


That was an outstanding explanation, thank you! Also, I’ve done quite a bit of additional research since posting that, so have answered a fair amount of my question.

Thank you for your reply.
.
Fluffy Pancakes

User ID: 54806596
United States
02/10/2020 11:46 AM

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Re: Coronavirus Intel Clearinghouse
Coronavirus and possible treatment options by Dr. Paul Cottrell


 Quoting: Anonymous Coward 66662033


Can you give a redux? 42 minutes. Too long for me atm.
Things are bad enough, there is no need to make anything up.

"Never interrupt an enemy in the process of destroying himself."...Q
Anonymous Coward
User ID: 78402365
Canada
02/10/2020 12:56 PM
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Re: Coronavirus Intel Clearinghouse
OP, I’m not a medical professional. However, based on my “layman” research, it’s clear that this virus is similar to SARS in many respects.

I’m finding conflicting information in the matter of ACE-2 that I’m hoping you may clarify.

I’m finding some articles advocating for increasing ACE2 levels to protect against lowered values caused by infection, yet other articles seem to indicate that inhibition of ACE-2 helps to prevent infection.

Can you please offer your insights and recommendations?

Thanks in advance. I’m tracking this thread several times a day for updates.
.
 Quoting: Anonymous Coward 75214035


Hello 011, from another thread:

The wuhan virus is identical to the ACE2 key-- and it fits into the keyhole.

So-- flooding the body with ACE2 would be a means of sopping up the virus-- NOT inhibiting ACE2.


What's your take on that.. some suggested ACE2 inhibitors, but this person thinks it could make matters worse.
 Quoting: Anonymous Coward 78455686


^^these!!
Would taking an ACE inhibitor for already high blood pressure be beneficial or problematic?
 Quoting: Anonymous Coward 75833332


The ACE2 receptor is merely the route of ingress of NCoV INTO the cell—it does nothing else. Overdosing on ACE2 inhibitor meds would have very serious cardiovascular/vasopressin results. I would recommend NOT doing this. Same with ARBs, the receptor site(ACE2) is complex. Wish it were

Once inside the cell it disables the Tregulator cells which is what is used to inhibit the positive feedback loop cytokines storm

Vit D plays a part in the formulation/differentiation of the myloproliferative cell into a Tregulator cell
 Quoting: Bodiless



ACE2 is also not the only receptor that it is using, this is just me and my colleagues coming to this possibility.

Our lab has not studied transmission or much of anything related to such. But just from provided facts here vs information regarding other viruses known to utilize ACE2 receptors, it just does not click.

SARS is known and proven to use ACE2 only.
Ncov is reported, to use ACE2 "only".

Sars, 13 months, less lethal by far, less infectious.

Ncov is clearly able to enter by other means, atleast I have come to accept this myself.

Medications/methods to prevent infection are priority 1. Treatment is secondary in nature as you would hope prevention is successful.

Remdesivir is still being touted in media, disregarding the fact it has adverse, unstudied side effects that are disregarded as this is an antiviral used in HIV cases.

It is intended to stop RNA based viral replication, it does do its job as intended, but it is neither effective enough or safe enough to use as a fulltime treatment.

-001
Anonymous Coward
User ID: 78402365
Canada
02/10/2020 01:00 PM
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Re: Coronavirus Intel Clearinghouse
Let me correct.

Remdesivir is used in many viral cases where the virus is proven to be worse than said side effects.

It is not used solely for hiv.

A well known example will be Ebola.

Where side effects are preferred to death.
Hearing and seeing remdesivir being used was not a good sign.

-001
Anonymous Coward
User ID: 78402365
Canada
02/10/2020 01:07 PM
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Re: Coronavirus Intel Clearinghouse
As well as the fact we cannot perform any testing here with it as it is not fda approved.

During many large outbreaks, we see many manufacturers produce a "miracle medicine" thay works on all virus, or bacteria, fungus or whatever the next fear wave is.

Hence the restriction in place, fda approved, proven and passed live trial and able to be produced in large amounts. This last restriction is difficult, as will become more and more evident the longer China is at a full halt.

-001
Anonymous Coward
User ID: 78384741
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02/10/2020 01:11 PM
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Re: Coronavirus Intel Clearinghouse
thanks for posting again...please ignore the village idiots...HOW CAN WE HELP YOU??there is an army here,what information can we find you to help? Also do you have any information on late stage lyme disease?I can tell you lots about it if you wanna exchange notes before it kills me...thanx in advance..Cheers!!!!!
Anonymous Coward
User ID: 76862206
United States
02/10/2020 01:16 PM
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Re: Coronavirus Intel Clearinghouse
001 says:
“Medications/methods to prevent infection are priority”

Suggestions?

.
Anonymous Coward
User ID: 19636877
United States
02/10/2020 01:24 PM
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Re: Coronavirus Intel Clearinghouse
As well as the fact we cannot perform any testing here with it as it is not fda approved.

During many large outbreaks, we see many manufacturers produce a "miracle medicine" thay works on all virus, or bacteria, fungus or whatever the next fear wave is.

Hence the restriction in place, fda approved, proven and passed live trial and able to be produced in large amounts. This last restriction is difficult, as will become more and more evident the longer China is at a full halt.

-001
 Quoting: Anonymous Coward 78402365


001, VERY SERIOUS QUESTION,

Are you ever allowed to run a single "rouge? test in your lab, or does everything you test have to have proper approvals?

AKA, if somebody had an cure that they wanted you to test that was not FDA approved, would that be possible for you to even try?

-R
NotStarvingActress

User ID: 77515635
United States
02/10/2020 02:27 PM
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Re: Coronavirus Intel Clearinghouse
Would there be any way to speed to the normally required extensive clinical trials on new drugs?

Know that those who are seriously ill with Wu Flu would rather take a risk and be essentially experimented on if they have a chance at recovery and to help others.
galvanic

User ID: 76596759
United States
02/10/2020 02:30 PM
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Re: Coronavirus Intel Clearinghouse
I have used Sambucol (Black Elderberry Syrup) for myself and family members for more than 20 years to stop influenza A or B from replicating. It is effective within 3 days. There is NIH research that backs this up.

My question is: is there any possibility that it would also stop the replication of the Corona virus? Conversely, could it amplify an undesirable response?

Here is the link: [link to www.ncbi.nlm.nih.gov (secure)]

and another one:

[link to www.ncbi.nlm.nih.gov (secure)]
galvanic
Vasily

User ID: 72304389
United States
02/10/2020 02:35 PM

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Re: Coronavirus Intel Clearinghouse
As well as the fact we cannot perform any testing here with it as it is not fda approved.

During many large outbreaks, we see many manufacturers produce a "miracle medicine" thay works on all virus, or bacteria, fungus or whatever the next fear wave is.

Hence the restriction in place, fda approved, proven and passed live trial and able to be produced in large amounts. This last restriction is difficult, as will become more and more evident the longer China is at a full halt.

-001
 Quoting: Anonymous Coward 78402365


001, VERY SERIOUS QUESTION,

Are you ever allowed to run a single "rouge? test in your lab, or does everything you test have to have proper approvals?

AKA, if somebody had an cure that they wanted you to test that was not FDA approved, would that be possible for you to even try?

-R
 Quoting: Anonymous Coward 19636877


No offense intended, brother, but the word you are trying to use is "rogue".

Rouge is something used in cosmetics.
Anonymous Coward
User ID: 78440777
Canada
02/10/2020 02:46 PM
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Re: Coronavirus Intel Clearinghouse
Let me correct.

Remdesivir is used in many viral cases where the virus is proven to be worse than said side effects.

It is not used solely for hiv.

A well known example will be Ebola.

Where side effects are preferred to death.
Hearing and seeing remdesivir being used was not a good sign.

-001
 Quoting: Anonymous Coward 78402365


Interferon?
Anonymous Coward
User ID: 72321131
United States
02/10/2020 03:06 PM
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Re: Coronavirus Intel Clearinghouse


SARS is known and proven to use ACE2 only.

Ncov is clearly able to enter by other means, atleast I have come to accept this myself.

-001
 Quoting: Anonymous Coward 75833332


I realize those other means may be unproven (as yet), but can you please advise on the other LIKELY methods of entry?

.
Fluffy Pancakes

User ID: 51775590
United States
02/10/2020 03:18 PM

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Re: Coronavirus Intel Clearinghouse
Welcome back, -001.

Is there any chance your lab will go to testing non FDA approved treatments? Like natural treatments?

I appreciate how busy you must be and thank you for staying with us on this.
Things are bad enough, there is no need to make anything up.

"Never interrupt an enemy in the process of destroying himself."...Q
Anonymous Coward
User ID: 75833332
Canada
02/10/2020 03:55 PM
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Re: Coronavirus Intel Clearinghouse
OP, I’m not a medical professional. However, based on my “layman” research, it’s clear that this virus is similar to SARS in many respects.

I’m finding conflicting information in the matter of ACE-2 that I’m hoping you may clarify.

I’m finding some articles advocating for increasing ACE2 levels to protect against lowered values caused by infection, yet other articles seem to indicate that inhibition of ACE-2 helps to prevent infection.

Can you please offer your insights and recommendations?

Thanks in advance. I’m tracking this thread several times a day for updates.
.
 Quoting: Anonymous Coward 75214035


Hello 011, from another thread:

The wuhan virus is identical to the ACE2 key-- and it fits into the keyhole.

So-- flooding the body with ACE2 would be a means of sopping up the virus-- NOT inhibiting ACE2.


What's your take on that.. some suggested ACE2 inhibitors, but this person thinks it could make matters worse.
 Quoting: Anonymous Coward 78455686


^^these!!
Would taking an ACE inhibitor for already high blood pressure be beneficial or problematic?
 Quoting: Anonymous Coward 75833332


The ACE2 receptor is merely the route of ingress of NCoV INTO the cell—it does nothing else. Overdosing on ACE2 inhibitor meds would have very serious cardiovascular/vasopressin results. I would recommend NOT doing this. Same with ARBs, the receptor site(ACE2) is complex. Wish it were

Once inside the cell it disables the Tregulator cells which is what is used to inhibit the positive feedback loop cytokines storm

Vit D plays a part in the formulation/differentiation of the myloproliferative cell into a Tregulator cell
 Quoting: Bodiless


So if you're already taking an ace inhibitor for blood pressure, should you continue, increase, decrease or stop the dosage?
Anonymous Coward
User ID: 72321131
United States
02/10/2020 04:42 PM
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Re: Coronavirus Intel Clearinghouse
001, VERY SERIOUS QUESTION,

Are you ever allowed to run a single "rouge? test in your lab, or does everything you test have to have proper approvals?

AKA, if somebody had an cure that they wanted you to test that was not FDA approved, would that be possible for you to even try?

-R
 Quoting: Anonymous Coward 19636877


No offense intended, brother, but the word you are trying to use is "rogue".

Rouge is something used in cosmetics.
 Quoting: Vasily


....[ahem].... as an honorary member of the National Spelling Cop and Grammar Nazi Organization of America, I support this post.
.
Anonymous Coward
User ID: 72321131
United States
02/10/2020 04:45 PM
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Re: Coronavirus Intel Clearinghouse
Welcome back, -001.

Is there any chance your lab will go to testing non FDA approved treatments? Like natural treatments?

I appreciate how busy you must be and thank you for staying with us on this.
 Quoting: Fluffy Pancakes


He answered that in another post. Unfortunately, his lab can only test FDA-approved protocols.

.
Anonymous Coward
User ID: 78456536
Portugal
02/10/2020 04:57 PM
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Re: Coronavirus Intel Clearinghouse
001, VERY SERIOUS QUESTION,

Are you ever allowed to run a single "rouge? test in your lab, or does everything you test have to have proper approvals?

AKA, if somebody had an cure that they wanted you to test that was not FDA approved, would that be possible for you to even try?

-R
 Quoting: Anonymous Coward 19636877


No offense intended, brother, but the word you are trying to use is "rogue".

Rouge is something used in cosmetics.
 Quoting: Vasily


....[ahem].... as an honorary member of the National Spelling Cop and Grammar Nazi Organization of America, I support this post.
.
 Quoting: Anonymous Coward 72321131


As an honorary member of living life thus far only to find everything has been a lie.

Now it seems we have almost copulation of -100 + -R ???

Trying not to be mean but as I am an old GuLP'er. Perhaps we should await star-child...
Anonymous Coward
User ID: 19636877
United States
02/10/2020 05:28 PM
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Re: Coronavirus Intel Clearinghouse
As well as the fact we cannot perform any testing here with it as it is not fda approved.

During many large outbreaks, we see many manufacturers produce a "miracle medicine" thay works on all virus, or bacteria, fungus or whatever the next fear wave is.

Hence the restriction in place, fda approved, proven and passed live trial and able to be produced in large amounts. This last restriction is difficult, as will become more and more evident the longer China is at a full halt.

-001
 Quoting: Anonymous Coward 78402365


001, VERY SERIOUS QUESTION,

Are you ever allowed to run a single "rouge? test in your lab, or does everything you test have to have proper approvals?

AKA, if somebody had an cure that they wanted you to test that was not FDA approved, would that be possible for you to even try?

-R
 Quoting: Anonymous Coward 19636877



No offense intended, brother, but the word you are trying to use is "rogue".

Rouge is something used in cosmetics.
 Quoting: Vasily


lol, thank you and nice catch. Its been a long week for me as well.....
Anonymous Coward
User ID: 19636877
United States
02/10/2020 05:32 PM
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Re: Coronavirus Intel Clearinghouse
001, VERY SERIOUS QUESTION,

Are you ever allowed to run a single "rouge? test in your lab, or does everything you test have to have proper approvals?

AKA, if somebody had an cure that they wanted you to test that was not FDA approved, would that be possible for you to even try?

-R
 Quoting: Anonymous Coward 19636877


No offense intended, brother, but the word you are trying to use is "rogue".

Rouge is something used in cosmetics.
 Quoting: Vasily


....[ahem].... as an honorary member of the National Spelling Cop and Grammar Nazi Organization of America, I support this post.
.
 Quoting: Anonymous Coward 72321131


As an honorary member of living life thus far only to find everything has been a lie.

Now it seems we have almost copulation of -100 + -R ???

Trying not to be mean but as I am an old GuLP'er. Perhaps we should await star-child...
 Quoting: Anonymous Coward 78456536


Perhaps you should keep your comments to yourself and keep to the topic at hand. Noone cares how long you have been on this site, and I can promise you, i have been on here longer
N3m3s1s

User ID: 75327296
United States
02/10/2020 07:10 PM

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Re: Coronavirus Intel Clearinghouse
Welcome back -001!
RedDevil3056

User ID: 77846703
United States
02/10/2020 07:35 PM
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Re: Coronavirus Intel Clearinghouse
At a rally in New Hampshire President Trump just said he hopes in April the virus will go away when the weather gets warmer. Our 11 cases are getting better everyday.

Last Edited by RedDevil3056 on 02/10/2020 07:41 PM
RedDevil3056
N3m3s1s

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02/10/2020 07:57 PM

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Re: Coronavirus Intel Clearinghouse
OP, I’m not a medical professional. However, based on my “layman” research, it’s clear that this virus is similar to SARS in many respects.

I’m finding conflicting information in the matter of ACE-2 that I’m hoping you may clarify.

I’m finding some articles advocating for increasing ACE2 levels to protect against lowered values caused by infection, yet other articles seem to indicate that inhibition of ACE-2 helps to prevent infection.

Can you please offer your insights and recommendations?

Thanks in advance. I’m tracking this thread several times a day for updates.
.
 Quoting: Anonymous Coward 75214035


Hello 011, from another thread:

The wuhan virus is identical to the ACE2 key-- and it fits into the keyhole.

So-- flooding the body with ACE2 would be a means of sopping up the virus-- NOT inhibiting ACE2.


What's your take on that.. some suggested ACE2 inhibitors, but this person thinks it could make matters worse.
 Quoting: Anonymous Coward 78455686


^^these!!
Would taking an ACE inhibitor for already high blood pressure be beneficial or problematic?
 Quoting: Anonymous Coward 75833332


The ACE2 receptor is merely the route of ingress of NCoV INTO the cell—it does nothing else. Overdosing on ACE2 inhibitor meds would have very serious cardiovascular/vasopressin results. I would recommend NOT doing this. Same with ARBs, the receptor site(ACE2) is complex. Wish it were

Once inside the cell it disables the Tregulator cells which is what is used to inhibit the positive feedback loop cytokines storm

Vit D plays a part in the formulation/differentiation of the myloproliferative cell into a Tregulator cell
 Quoting: Bodiless




ACE2 is also not the only receptor that it is using, this is just me and my colleagues coming to this possibility.

Our lab has not studied transmission or much of anything related to such. But just from provided facts here vs information regarding other viruses known to utilize ACE2 receptors, it just does not click.

SARS is known and proven to use ACE2 only.
Ncov is reported, to use ACE2 "only".

Sars, 13 months, less lethal by far, less infectious.

Ncov is clearly able to enter by other means, atleast I have come to accept this myself.

Medications/methods to prevent infection are priority 1. Treatment is secondary in nature as you would hope prevention is successful.

Remdesivir is still being touted in media, disregarding the fact it has adverse, unstudied side effects that are disregarded as this is an antiviral used in HIV cases.

It is intended to stop RNA based viral replication, it does do its job as intended, but it is neither effective enough or safe enough to use as a fulltime treatment.

-001
 Quoting: Anonymous Coward 78402365


Is the plan to put the entire planet on Anti-Virals or some other type of preventive treatments? That would not be feasible nor possible. You discussed many times that vaccines could not be developed due to mutation rates etc. So what would prevent infection that is in the FDA toolbox?

Also, have to go through your posts I’ve cataloged, but thought you said that treatment was priority 1? Has something changed?





GLP