Coronavirus Intel Clearinghouse | |
TlvmmCpoft
User ID: 77347043 Poland 02/08/2020 07:56 PM Report Abusive Post Report Copyright Violation | Mr dull socks Quoting: Anonymous Coward 78453998 You are correct in saying you are most infected before showing symptoms and following symptoms are simply your immune system responding. In data I have seen, this is not reflective of all cases, this is what ncov seems best at to be honest. Causing a very very large immuno-response. Cytokine storm as many here will have seen. I believe fevers may be aiding this issue as well as it is known that fevers aid your immune response. It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it. It is a complex and dynamic situation that we are simply trying to get ahead of as containment is just not a very efficient option. "Containment" can be done, but it will cost far more lives, money and long term damage then the current route as in my opinion, only mass quarantine is the way to contain, which will turn "camps" into a human petri dish. -001 "It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it." wow Yeah. That's been my major problem with facing it. Do I treat it like cytokine storm or AIDS? And how the fuck do you treat both at the same time? I don't know what lies they told you, but I can promise they were lies. There's a fine line between training, trauma, and torture. |
Anonymous Coward User ID: 78402365 Canada 02/08/2020 07:58 PM Report Abusive Post Report Copyright Violation | Mr dull socks Quoting: Anonymous Coward 78453998 You are correct in saying you are most infected before showing symptoms and following symptoms are simply your immune system responding. In data I have seen, this is not reflective of all cases, this is what ncov seems best at to be honest. Causing a very very large immuno-response. Cytokine storm as many here will have seen. I believe fevers may be aiding this issue as well as it is known that fevers aid your immune response. It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it. It is a complex and dynamic situation that we are simply trying to get ahead of as containment is just not a very efficient option. "Containment" can be done, but it will cost far more lives, money and long term damage then the current route as in my opinion, only mass quarantine is the way to contain, which will turn "camps" into a human petri dish. -001 "It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it." wow This was evident from a lower white blood cell count + presence of cytokine storms. -001 |
Anonymous Coward User ID: 78402365 Canada 02/08/2020 08:00 PM Report Abusive Post Report Copyright Violation | Mr dull socks Quoting: Anonymous Coward 78453998 You are correct in saying you are most infected before showing symptoms and following symptoms are simply your immune system responding. In data I have seen, this is not reflective of all cases, this is what ncov seems best at to be honest. Causing a very very large immuno-response. Cytokine storm as many here will have seen. I believe fevers may be aiding this issue as well as it is known that fevers aid your immune response. It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it. It is a complex and dynamic situation that we are simply trying to get ahead of as containment is just not a very efficient option. "Containment" can be done, but it will cost far more lives, money and long term damage then the current route as in my opinion, only mass quarantine is the way to contain, which will turn "camps" into a human petri dish. -001 "It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it." wow Yeah. That's been my major problem with facing it. Do I treat it like cytokine storm or AIDS? And how the fuck do you treat both at the same time? Hopefully with a treatment manufacturable 100% by ourselves. Including 100% of said ingredients and factories. -001 |
Anonymous Coward User ID: 78305299 Canada 02/08/2020 08:02 PM Report Abusive Post Report Copyright Violation | WARNING!!!! Quoting: Anonymous Coward 76166984 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! They are doing this LARP for clicks and ad revenue and spreading fear to make money. Half of what 001 has said is pulled directly off of 4chan and twitter, anyone who thinks someone from the government is continuing to leak info here without already being arrested is an idiot, part of the LARP or a fucking dimwit. Think about it. Trinity basically bans all proxy vpns but somehow this 001 manages to get through? Why is anyone questioning the story get deleted and banned? 001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!! 4chan I am not on If what I am being said is repeated, it is not me. Can you provide a link for me to verify? Or others please -001 |
sssssteve
User ID: 78452600 United States 02/08/2020 08:08 PM Report Abusive Post Report Copyright Violation | Mr dull socks Quoting: Anonymous Coward 78453998 You are correct in saying you are most infected before showing symptoms and following symptoms are simply your immune system responding. In data I have seen, this is not reflective of all cases, this is what ncov seems best at to be honest. Causing a very very large immuno-response. Cytokine storm as many here will have seen. I believe fevers may be aiding this issue as well as it is known that fevers aid your immune response. It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it. It is a complex and dynamic situation that we are simply trying to get ahead of as containment is just not a very efficient option. "Containment" can be done, but it will cost far more lives, money and long term damage then the current route as in my opinion, only mass quarantine is the way to contain, which will turn "camps" into a human petri dish. -001 "It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it." wow Yeah. That's been my major problem with facing it. Do I treat it like cytokine storm or AIDS? And how the fuck do you treat both at the same time? ASK YOURSELF. Why is the OWL banning people who question who 001 really is? The Aids thing has already been debunked and everything 001 is saying is taken right off of 4chan! WARNING!!!! 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! They are doing this LARP for clicks and ad revenue and spreading fear to make money. Half of what 001 has said is pulled directly off of 4chan and twitter, anyone who thinks someone from the government is continuing to leak info here without already being arrested is an idiot, part of the LARP or a fucking dimwit. Think about it. Trinity basically bans all proxy vpns but somehow this 001 manages to get through? Why is anyone questioning the story get deleted and banned? 001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!! I'll repeat, as was stated earlier in the thread, this thread was created for people who wanted to read 01's posts. No one is forcing you to read the thread. There are many other threads available for your viewing pleasure. |
Anonymous Coward User ID: 78305299 Canada 02/08/2020 08:09 PM Report Abusive Post Report Copyright Violation | |
mr dull socks
User ID: 78401556 United States 02/08/2020 08:12 PM Report Abusive Post Report Copyright Violation | Mr dull socks Quoting: Anonymous Coward 78453998 You are correct in saying you are most infected before showing symptoms and following symptoms are simply your immune system responding. In data I have seen, this is not reflective of all cases, this is what ncov seems best at to be honest. Causing a very very large immuno-response. Cytokine storm as many here will have seen. I believe fevers may be aiding this issue as well as it is known that fevers aid your immune response. It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it. It is a complex and dynamic situation that we are simply trying to get ahead of as containment is just not a very efficient option. "Containment" can be done, but it will cost far more lives, money and long term damage then the current route as in my opinion, only mass quarantine is the way to contain, which will turn "camps" into a human petri dish. -001 "It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it." wow Yeah. That's been my major problem with facing it. Do I treat it like cytokine storm or AIDS? And how the fuck do you treat both at the same time? As i have mentioned i would do D3 and nano silver. nano silver has been tested against HIV in many studies however to date i do not think the nanometer size has been small enough to produce the desired results. In this study... [link to www.ncbi.nlm.nih.gov (secure)] they test 30-50nm which is WAY to large for uptake. the nanometer size needs to be down closer to 1-10nm to produce desired efficacy. A DARPA funded study that i reviewed showed nano silver to be effective against monkey pox (ebola) and coronavirus. unfortunately i do not think this will help 001 because these are not FDA approved protocols... |
Anonymous Coward User ID: 74451591 United States 02/08/2020 08:12 PM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 77574563 Australia 02/08/2020 08:14 PM Report Abusive Post Report Copyright Violation | WARNING!!!! Quoting: Anonymous Coward 76166984 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! They are doing this LARP for clicks and ad revenue and spreading fear to make money. Half of what 001 has said is pulled directly off of 4chan and twitter, anyone who thinks someone from the government is continuing to leak info here without already being arrested is an idiot, part of the LARP or a fucking dimwit. Think about it. Trinity basically bans all proxy vpns but somehow this 001 manages to get through? Why is anyone questioning the story get deleted and banned? 001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!! I am on a VPN and I am accessing GLP just fine. |
Anonymous Coward User ID: 72333614 United States 02/08/2020 08:17 PM Report Abusive Post Report Copyright Violation | ... Quoting: Anonymous Coward 66662033 What about the damage the Wuhan virus is doing to the body and people in China showing now symptoms asymptomatic falling over and dying coz the virus is attacking the heart, brain, oprgans, cns? What will Vitamin D do for the incubation period? Your body is the most sick BEFORE you show symptoms. Or to say it more accurately you have the highest viral load before you start to show symptoms. If your body has not taken care of the pathogen by other means it will literally try to expel the pathogen from the body. cough, sneeze, runny nose, etc. If you have enough free D3 in your blood stream many people will never reach the symptomatic stage (or have very mild symptoms) because when the pathogen enters into the body, the D3 will go to your brain, be encoded with instructions, and rush out the the cells to give them the instructions. Keep in mind that once the D is used up it must be replenished that is why i was suggesting a mega dose at first sign of symptoms (50,000 iu). likely your body needs more D3 to finish of the pathogen. also D3 regulates cardiac function, so theres that too. What about this reply here on the thread I started Corona Virus Vitamin D: Thread: Corona Virus Vitamin D He says: "If you think that you're just going to take some Vit D and be ok you are dreaming. It take months to build up your immune system and firstly you have to be mineralised, hydrated and you biome has to be healthy." His statement is half true. It does indeed take months to build up sufficient 25-OHD levels in your body. 25OHD is a prehormone created by the liver and indicates the constant level of Free D3 in your blood. If you just took on large dose of D3 it would not significantly increase your 25OHD you would simply pee most of it out. however for a short period of time it is in your bloodstream and available for your body to use. If you have sufficient 25 OHD levels you dont need to mega dose because your body already has all of the free D3 it needs. However most people have very low 25OHD levels, Hence the mega dose i suggested. the mega dose creates a sufficient D3 level for your body to use for a short period of time. He is also correct in that this isnt the only thing that one needs to do to protect themselves. but it is the best thing you can do to prevent a cytokine storm, which is the initial point i made. What else do we need to be doing to protect ourselves? |
Anonymous Coward User ID: 78434683 United States 02/08/2020 08:18 PM Report Abusive Post Report Copyright Violation | |
Epic Beard Guy
User ID: 76783046 United States 02/08/2020 08:18 PM Report Abusive Post Report Copyright Violation | Has the possibility of using H1 and H2 antagonists for a cytokine storm been discussed on this thread? Quoting: Anonymous Coward 74451591 Elderberry syrup or other elderberry supplements will help stop Cytokine storm. If you have elderberries growing nearby, remember they have to be boiled. Preserve the juice in honey or high proof alcohol. Hope for the best, but prepare for the worst. "America is at that awkward stage. It's too late to work within the system, but too early to shoot the bastards." -- Claire Wolfe |
Epic Beard Guy
User ID: 76783046 United States 02/08/2020 08:19 PM Report Abusive Post Report Copyright Violation | Can animals get infected, carry and transmit it? Quoting: Anonymous Coward 78434683 Will freezing kill it? Are children getting symptoms? The youngest reported victim was 36 hours old. Hope for the best, but prepare for the worst. "America is at that awkward stage. It's too late to work within the system, but too early to shoot the bastards." -- Claire Wolfe |
sssssteve
User ID: 78452600 United States 02/08/2020 08:20 PM Report Abusive Post Report Copyright Violation | WARNING!!!! Quoting: Anonymous Coward 76166984 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! 001 is in fact Trinity or one of the MODS!!!!!!! They are doing this LARP for clicks and ad revenue and spreading fear to make money. Half of what 001 has said is pulled directly off of 4chan and twitter, anyone who thinks someone from the government is continuing to leak info here without already being arrested is an idiot, part of the LARP or a fucking dimwit. Think about it. Trinity basically bans all proxy vpns but somehow this 001 manages to get through? Why is anyone questioning the story get deleted and banned? 001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!!001 is in fact Trinity or one of the MODS!!!!!!! I am on a VPN and I am accessing GLP just fine. yeah, I have a VPN on my other computer and I can access GLP |
NeD RyeRsON
User ID: 75619389 United States 02/08/2020 08:22 PM Report Abusive Post Report Copyright Violation | |
Scorpionica
User ID: 10368710 United States 02/08/2020 08:23 PM Report Abusive Post Report Copyright Violation | Thoughts on the 5 new cases in France overnight and today's reports about onward transmission originating in Singapore and then on to France and the UK? "An unfailing experience of mundane events in harmony with the changes occurring in the heavens has instructed and compelled my unwilling belief." Johannes Kepler "And God said, Let there be lights in the firmament of the heaven to divide the day from the night; and let them be for signs, and for seasons, and for days, and years..." Genesis 1:14 |
Epic Beard Guy
User ID: 76783046 United States 02/08/2020 08:24 PM Report Abusive Post Report Copyright Violation | I heard nicotine might help, but smoking definitely makes it worse. Maybe a patch? Hope for the best, but prepare for the worst. "America is at that awkward stage. It's too late to work within the system, but too early to shoot the bastards." -- Claire Wolfe |
Anonymous Coward User ID: 78305299 Canada 02/08/2020 08:25 PM Report Abusive Post Report Copyright Violation | Can animals get infected, carry and transmit it? Quoting: Anonymous Coward 78434683 Will freezing kill it? Are children getting symptoms? The youngest reported victim was 36 hours old. No reported symptoms or death unless I have missed something? China has provided not one real report yet for anyone except themselves. -001 |
Hub Cap Halo
User ID: 76712268 United States 02/08/2020 08:25 PM Report Abusive Post Report Copyright Violation | ON TOPIC MIDNIGHT RIDE LIVE AT 11 PM EASTERN [link to www.youtube.com (secure)] Watching through the Lattice |
Anonymous Coward User ID: 72333614 United States 02/08/2020 08:25 PM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 77997687 France 02/08/2020 08:27 PM Report Abusive Post Report Copyright Violation | I doubt a lab worker working on this actually has the time to continuously post on here, and it's doubtful they allow cellphones in a secure lab so the chances of this being real are very low and more likely some intern or college kid showing his textbook skills off to freak people out. |
mr dull socks
User ID: 78401556 United States 02/08/2020 08:27 PM Report Abusive Post Report Copyright Violation | You are correct in saying you are most infected before showing symptoms and following symptoms are simply your immune system responding. Quoting: -001In data I have seen, this is not reflective of all cases, this is what ncov seems best at to be honest. Causing a very very large immuno-response. Cytokine storm as many here will have seen. I believe fevers may be aiding this issue as well as it is known that fevers aid your immune response. It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it. It is a complex and dynamic situation that we are simply trying to get ahead of as containment is just not a very efficient option. "Containment" can be done, but it will cost far more lives, money and long term damage then the current route as in my opinion, only mass quarantine is the way to contain, which will turn "camps" into a human petri dish. -001 -001: What is the best way to calm the cytokine storm if a person is to contract this nCov? I've read here on GLP that a combo of 3 OTC meds can help the storm, I believe it was antihistamine like Benadryl or related, taken together with OTC Zantac and OTC Prilosec would take care of 3 components of immune response to foreign invader that the lymphocytes are trying to react to. Whats your take on this? Also, would it be advised once you have a fever to need to also take ibuprofen and acetaminophen? At this point i would NOT advise at any fever reduction. (i could be wrong but if i get it i will not attempt to reduce fever) although it is true that fever excites the immune system it also directly effects the viral replication process by slowing its ability to replicate. cytokine storms appear in the presence of high viral loads, so anything that slows the viral load is good. slowing the replication process give your immune system a chance to reduce the viral load, thus prevent the subsequent cytokine storm. |
Anonymous Coward User ID: 78305299 Canada 02/08/2020 08:29 PM Report Abusive Post Report Copyright Violation | Not sure that it's a 4chan LARP, but I also saw the guy on 4chan pretending to be a lab worker over there. it's actually pinned as one of the posts on GLP. there have been a bunch of 4chan LARPS going around including the latest this is the zombie virus one. Quoting: Anonymous Coward 77997687 I doubt a lab worker working on this actually has the time to continuously post on here, and it's doubtful they allow cellphones in a secure lab so the chances of this being real are very low and more likely some intern or college kid showing his textbook skills off to freak people out. Considering I do not post while in lab due to to being impossible for service and security reasons alike and I am not overseas. -001 |
Anonymous Coward User ID: 78305299 Canada 02/08/2020 08:35 PM Report Abusive Post Report Copyright Violation | You are correct in saying you are most infected before showing symptoms and following symptoms are simply your immune system responding. Quoting: -001In data I have seen, this is not reflective of all cases, this is what ncov seems best at to be honest. Causing a very very large immuno-response. Cytokine storm as many here will have seen. I believe fevers may be aiding this issue as well as it is known that fevers aid your immune response. It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it. It is a complex and dynamic situation that we are simply trying to get ahead of as containment is just not a very efficient option. "Containment" can be done, but it will cost far more lives, money and long term damage then the current route as in my opinion, only mass quarantine is the way to contain, which will turn "camps" into a human petri dish. -001 -001: What is the best way to calm the cytokine storm if a person is to contract this nCov? I've read here on GLP that a combo of 3 OTC meds can help the storm, I believe it was antihistamine like Benadryl or related, taken together with OTC Zantac and OTC Prilosec would take care of 3 components of immune response to foreign invader that the lymphocytes are trying to react to. Whats your take on this? Also, would it be advised once you have a fever to need to also take ibuprofen and acetaminophen? At this point i would NOT advise at any fever reduction. (i could be wrong but if i get it i will not attempt to reduce fever) although it is true that fever excites the immune system it also directly effects the viral replication process by slowing its ability to replicate. cytokine storms appear in the presence of high viral loads, so anything that slows the viral load is good. slowing the replication process give your immune system a chance to reduce the viral load, thus prevent the subsequent cytokine storm. I would agree 100% except wih ncov. You are correct though. But cases are exhibiting fever for 5-7 days. At a high temp as well. In hospital care, that is ideal. In a home situation due to overloaded hospital systems, a fever of 103+, shortness of breath that continues to deteriotate. Meaning many will end uo bedridden, malnourished, and worse off. Perhaps I am wrong? -001 |
akasuzanne
User ID: 78185358 United States 02/08/2020 08:41 PM Report Abusive Post Report Copyright Violation | I did not expect this to grow as such. Quoting: Anonymous Coward 78402365 I hope some of you watched the CDC briefing as thats as close to verification of what I said before it aired withiut risking myself. Regarding treatments, my colleagues and I are looking at fda approved antivirals, experimental antivirals and past effective treatments on prominent viral outbreaks. If it hasnt been tested or proven, unfortunately we are not looking at it at this time in this specific facility. Working with the government requires you to follow their rules unfortunately, and to admit a non-approved therapy has effects, is not in their interest. Speaking on fever. Yes, typically a fever is actually beneficial and should be allowed as it instigates your immune system. But with 19ncov, it may be aiding in causing a cytokine storm, this is unproven without live data, but is a theory we are bouncing around between colleagues. Again, this is 100% unproven without further testing, just a hypothesis from a fellow here. -001 Sorry if you have already answered this questions, but has AIDS medication been tested against this virus? BTW, A HUGE thankyou for all of your info. You have no idea how many people lives you are helping! Please dont let the trolls get you down. You have more power than you realize!(And continue to update this tread as you acquire more info) -R Remdesivir which is made by Gilead is currently under clinical trials in China, but there has not been sufficient evidence that it will be effective in the treatment. Instead it has shown to improve the standard of care in critically ill patients, but not provide treatment. AbbVie also has a version of remdesivir called Aluvia which is being explored as an option to treatment, but the product is not readily available for supportive treatment options. Another treatment option that has shown promise, and is being considered is taking a dose of lopinavir and ritonavir and then nebulizing alpha-interferon BID. -002 The case review of the first US patient in Washington used Remdesivir - they used it because he was in so much distress. The patient recovered. Interesting, I was reamed for posting the link to the case report here. I mentioned it answers a lot of questions. It is back on page 5 or 6 with a link. |
Anonymous Coward User ID: 78305299 Canada 02/08/2020 08:42 PM Report Abusive Post Report Copyright Violation | |
mr dull socks
User ID: 78401556 United States 02/08/2020 08:43 PM Report Abusive Post Report Copyright Violation | You are correct in saying you are most infected before showing symptoms and following symptoms are simply your immune system responding. Quoting: -001In data I have seen, this is not reflective of all cases, this is what ncov seems best at to be honest. Causing a very very large immuno-response. Cytokine storm as many here will have seen. I believe fevers may be aiding this issue as well as it is known that fevers aid your immune response. It seems that the virus is doing its best to cause your immune system to over-react while at the same time, destroying it. It is a complex and dynamic situation that we are simply trying to get ahead of as containment is just not a very efficient option. "Containment" can be done, but it will cost far more lives, money and long term damage then the current route as in my opinion, only mass quarantine is the way to contain, which will turn "camps" into a human petri dish. -001 -001: What is the best way to calm the cytokine storm if a person is to contract this nCov? I've read here on GLP that a combo of 3 OTC meds can help the storm, I believe it was antihistamine like Benadryl or related, taken together with OTC Zantac and OTC Prilosec would take care of 3 components of immune response to foreign invader that the lymphocytes are trying to react to. Whats your take on this? Also, would it be advised once you have a fever to need to also take ibuprofen and acetaminophen? At this point i would NOT advise at any fever reduction. (i could be wrong but if i get it i will not attempt to reduce fever) although it is true that fever excites the immune system it also directly effects the viral replication process by slowing its ability to replicate. cytokine storms appear in the presence of high viral loads, so anything that slows the viral load is good. slowing the replication process give your immune system a chance to reduce the viral load, thus prevent the subsequent cytokine storm. I would agree 100% except wih ncov. You are correct though. But cases are exhibiting fever for 5-7 days. At a high temp as well. In hospital care, that is ideal. In a home situation due to overloaded hospital systems, a fever of 103+, shortness of breath that continues to deteriotate. Meaning many will end uo bedridden, malnourished, and worse off. Perhaps I am wrong? -001 We had a very similar conundrum with H1N1 (although seemingly not as severe) my colleagues and i went back and forth on suggested protocol. In the end we settled on viral load being the most important factor determining outcome, therefore we focused on slowing down viral replication and focused on the best ways to reduce viral load. |
NeD RyeRsON
User ID: 75619389 United States 02/08/2020 08:43 PM Report Abusive Post Report Copyright Violation | I did not expect this to grow as such. Quoting: Anonymous Coward 78402365 I hope some of you watched the CDC briefing as thats as close to verification of what I said before it aired withiut risking myself. Regarding treatments, my colleagues and I are looking at fda approved antivirals, experimental antivirals and past effective treatments on prominent viral outbreaks. If it hasnt been tested or proven, unfortunately we are not looking at it at this time in this specific facility. Working with the government requires you to follow their rules unfortunately, and to admit a non-approved therapy has effects, is not in their interest. Speaking on fever. Yes, typically a fever is actually beneficial and should be allowed as it instigates your immune system. But with 19ncov, it may be aiding in causing a cytokine storm, this is unproven without live data, but is a theory we are bouncing around between colleagues. Again, this is 100% unproven without further testing, just a hypothesis from a fellow here. -001 Sorry if you have already answered this questions, but has AIDS medication been tested against this virus? BTW, A HUGE thankyou for all of your info. You have no idea how many people lives you are helping! Please dont let the trolls get you down. You have more power than you realize!(And continue to update this tread as you acquire more info) -R Remdesivir which is made by Gilead is currently under clinical trials in China, but there has not been sufficient evidence that it will be effective in the treatment. Instead it has shown to improve the standard of care in critically ill patients, but not provide treatment. AbbVie also has a version of remdesivir called Aluvia which is being explored as an option to treatment, but the product is not readily available for supportive treatment options. Another treatment option that has shown promise, and is being considered is taking a dose of lopinavir and ritonavir and then nebulizing alpha-interferon BID. -002 The case review of the first US patient in Washington used Remdesivir - they used it because he was in so much distress. The patient recovered. Interesting, I was reamed for posting the link to the case report here. I mentioned it answers a lot of questions. It is back on page 5 or 6 with a link. [link to www.medscape.com (secure)] Bing! |
Anonymous Coward User ID: 77997687 France 02/08/2020 08:46 PM Report Abusive Post Report Copyright Violation | Not sure that it's a 4chan LARP, but I also saw the guy on 4chan pretending to be a lab worker over there. it's actually pinned as one of the posts on GLP. there have been a bunch of 4chan LARPS going around including the latest this is the zombie virus one. Quoting: Anonymous Coward 77997687 I doubt a lab worker working on this actually has the time to continuously post on here, and it's doubtful they allow cellphones in a secure lab so the chances of this being real are very low and more likely some intern or college kid showing his textbook skills off to freak people out. Considering I do not post while in lab due to to being impossible for service and security reasons alike and I am not overseas. -001 So with something this big going on, they let you guys have the weekend off? That seems pretty odd! |
Anonymous Coward User ID: 78305299 Canada 02/08/2020 08:49 PM Report Abusive Post Report Copyright Violation | ... Quoting: Peace0ut -001: What is the best way to calm the cytokine storm if a person is to contract this nCov? I've read here on GLP that a combo of 3 OTC meds can help the storm, I believe it was antihistamine like Benadryl or related, taken together with OTC Zantac and OTC Prilosec would take care of 3 components of immune response to foreign invader that the lymphocytes are trying to react to. Whats your take on this? Also, would it be advised once you have a fever to need to also take ibuprofen and acetaminophen? At this point i would NOT advise at any fever reduction. (i could be wrong but if i get it i will not attempt to reduce fever) although it is true that fever excites the immune system it also directly effects the viral replication process by slowing its ability to replicate. cytokine storms appear in the presence of high viral loads, so anything that slows the viral load is good. slowing the replication process give your immune system a chance to reduce the viral load, thus prevent the subsequent cytokine storm. I would agree 100% except wih ncov. You are correct though. But cases are exhibiting fever for 5-7 days. At a high temp as well. In hospital care, that is ideal. In a home situation due to overloaded hospital systems, a fever of 103+, shortness of breath that continues to deteriotate. Meaning many will end uo bedridden, malnourished, and worse off. Perhaps I am wrong? -001 We had a very similar conundrum with H1N1 (although seemingly not as severe) my colleagues and i went back and forth on suggested protocol. In the end we settled on viral load being the most important factor determining outcome, therefore we focused on slowing down viral replication and focused on the best ways to reduce viral load. If we had viable treatment, I would agree 100% as targetting the viral load will reduce the immune response, in turn allowing the fevers benefits to outweigh its cons to how the patient will behave and nourish themselves. -001 |